Jamal Saada, MSc.
Instructor, Division of Gastroenterology and Hepatology
Jamal Saada, MSc.
Department of Internal Medicine
University of Texas Medical Branch
301 University Blvd.
Galveston, TX 77555-0655
Mr. Saada received a B.Sc. degree from the Ben Gurion University where he majored in biochemistry and molecular biology and M.Med.Sc degree in health sciences from the Ben Gurion University of the Negev located in Beer-Sheva, Israel.
Mr. Saada joined UTMB in 1992 as a visiting scientist in the Department of Pathology working on the molecular aspects of spotted fever group ricketssiae. Currently he is an instructor in the Division of Gastroenterology and Hepatology in the Department of Internal Medicine at The University of Texas Medical Branch (UTMB) in Galveston. He works with Dr. Don Powell as a co-investigator on 2 NIH grants.
Mr. Saada's research focuses on the intestinal myofibroblasts/fibroblasts biology, especially their contribution to colon cancer through interactions with the intestinal epithelium in the colonic mucosa. His research interests also include the immune functions of the intestinal myofibroblasts/fibroblasts in IBD.
- Mifflin RC, Pinchuk IV, Saada JI, Powell DW. Intestinal myofibroblasts: targets for stem cell therapy. Am J Physiol Gastrointest Liver Physiol. 2011 Jan 20. [Epub ahead of print] PubMed PMID: 21252048.
- Powell DW, Pinchuk IV, Saada JI Chen X, Mifflin RC. Mesenchymal Cells of the Intestinal Lamina Propria. Annu Rev Physiol. 2010 Feb 19. [Epub ahead of print] PubMed PMID: 21054163.
- Pinchuk IV, Mifflin RC, Saada JI Powell DW. Intestinal mesenchymal cells. Curr Gastroenterol Rep. 2010 Oct;12(5):310-8. PubMed PMID: 20690004; PubMed Central PMCID: PMC2975955.
- Pinchuk IV, Saada JI Beswick EJ, Boya G, Qiu SM, Mifflin RC, Raju GS, Reyes VE, Powell DW. PD-1 ligand expression by human colonic myofibroblasts/fibroblasts regulates CD4+ T-cell activity. Gastroenterology 135:1228-1237, 1237.e1-2. 2008
- Di Mari JF, Saada JI Mifflin RC, Valentich JD, Powell DW. HETEs Enhance IL-1-Mediated COX-2 Expression via Augmentation of Message Stability in Human Colonic Myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G719-28, 2007.
- Pinchuk IV, Beswick EJ, Saada JI Suarez G, Winston J, Mifflin RC, Di Mari JF, Powell DW, Reyes VE. Monocyte Chemoattractant Protein-1 Production by Intestinal Myofibroblasts in Response to Staphylococcal Enterotoxin A: Relevance to Staphylococcal Enterotoxigenic Disease. J Immunol 178:8097-106, 2007.
- Saada JI Pinchuk IV, Barrera CA, Adegboyega PA, Suarez G, Mifflin RC, Di Mari JF, Reyes VE, Powell DW. Subepithelial Myofibroblasts are Novel Nonprofessional APCs in the Human Colonic Mucosa. J Immunol 177: 5968-5979, 2006.
- Adegboyega PA, Ololade O, Saada J, Mifflin R, Di Mari JF, Powell DW. Subepithelial myofibroblasts express cyclooxygenase-2 in colorectal tubular adenomas. Clin Cancer Res. 1;10(17):5870-9, 2004.
- Di Mari JF, Mifflin RC, Adegboyega PA, Saada JI Powell DW. IL-1alpha-induced COX-2 expression in human intestinal myofibroblasts is dependent on a PKCzeta-ROS pathway. Gastroenterology 124(7): 1855-65, 2003.
The department of internal medicine is developing evidence based clinical protocols which will be available in EPIC (as order sets) for use when admitting patients with these diagnoses. Their AIM is to standardize care and decrease length of stay and readmission rates.Currently available protocols are:
- CAP - Community Acquired Pneumonia Orderset
- Congestive Heart Failure (CHF)
- Chronic Obstructive Pulmonary Disease (COPD)
- Diabetic Ketoacidosis Adult, ICU
- General Medicine Admission
- Immunodeficiency Flow Panel
- MICU/CCU Admission Order Set
- Oral Analgesic Medicaitons
- Parenteral Opioids
- Sepsis, Adult ICU
- 111 - Stroke Alert
- 112 - Stroke Activation
- 300086 - Stroke Floor Admission
- 3000000001 - Stroke Critical care without tPA
- 300088 Stroke - Transfer from Critical care to floor
- 3004002 - Stroke Discharge
All protocols can be found in the EPIC order set section.
The department of Internal Medicine has a large role in the Meaningful Use Initiative. Our participation is key for the success of the initiative. Please visit the meaningful use website for important communication and updates from the Meaningful Use Initiative.