Elena Volpi, M.D., Ph. D.
Professor, Department of Internal Medicine, Division of Geriatric Medicine
- Elena Volpi, M.D., Ph. D.
- Division of Geriatric Medicine
- University of Texas Medical Branch
- Galveston, TX 77550
|Degree/Training Completed||Year||Name & Location|
|M.D.||1989||University of Perugia, Italy|
|Internship–Internal Medicine||1989||University of Perugia, Italy|
|Residency–Endocrinology and Diabetes||1991||University of Perugia, Italy|
|Ph.D.||1995||University of Perugia, Italy|
- Italian Board of Medical Examiners
- Italian Board of Endocrinology
Publications: ARTICLES IN PEER REVIEWED JOURNALS:
- Volpi E, Liberman SA, Ferrer DM, Gilkison CR, Nagamani M, and Urban RJ. The relationship between testosterone, body composition and insulin sensitivity: a lesson from a case of extreme hyperandrogenism. Diabetes Care 28:479-432, 2005
- Bell JA, Fujita S, Volpi E, Cadenas JG, Rasmussen BB. Short-term insulin and nutritional energy administration do not stimulate muscle protein synthesis if blood amino acid availability decreases. Am J Physiol Endocrinol Metab 289:E999-E1006, 2005
- Rasmussen BB, Fujita S, Wolfe RR, Mittendorfer B, Roy M, Rowe VL, and Volpi E. Protein metabolism is resistant to the anabolic action of insulin in older human skeletal muscle. FASEB J. 20:768-769, 2006
- Bell JA, Volpi E, Fujita S, Cadenas JG, Sheffield-Moore M, and Rasmussen BB. The skeletal muscle protein anabolic response to increased energy and insulin is preserved in poorly controlled type 2 diabetes. J Nutr 136:1249-55, 2006
- Fujita S, Rasmmussen BB, Cadenas JG, Grady JJ, and Volpi E. The effect of insulin on human skeletal muscle protein synthesis is modulated by insulin-induced changes in muscle blood flow and amino acid availability. Am J Physiol Endocrinol Metab. 291:E745-E754, 2006
- Bell JA, Volpi E, Fujita S, Cadenas JG, Rasmussen BB. Dysregulation of Muscle Fatty Acid Metabolism in Type 2 Diabetes is Independent of Malonyl-CoA. Diabetologia. 49:2144-52, 2006
- Dreyer HC, Fujita S, Cadenas JG, Volpi E, Rasmussen BB. Resistance exercise increases AMPK activity and inhibits translation initiation and protein synthesis in human muscle. J Physiol. 576:613-24, 2006
- Sheffield-Moore M, Paddon Jones D, Casperson S, Gilkison CR, Volpi E, Wolf SL, Jiang J, Rosenblatt J, Urban RJ. Androgen therapy induces muscle protein anabolism in older women. J Clin Endocrinol Metab. 91:3844-3849, 2006
- Fujita S, Rasmussen BB, Bell JA, Cadenas JG, Volpi E. Muscle intracellular amino acid kinetics in women and men. Am J Physiol Endocrinol Metab. 292:77-83, 2007
- Fujita S, Rasmussen BB, Cadenas JG, Drummond MJ, Glynn EL, Sattler FR, and Volpi E. Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mTOR signaling. Diabetes 56:1615–1622, 2007
- Fujita S, Dreyer HC, Drummond MJ, Glynn EL, Cadenas JG, Yoshizawa F, Volpi E, and Rasmussen BB. Nutrient Signalling in the Regulation of Human Muscle Protein Synthesis. J Physiol 582(Pt 2):813-23, 2007
- Fujita S, Abe T, Drummond MJ, Cadenas JG, Dreyer HC, Sato Y, Volpi E, and Rasmussen BB. Blood Flow Restriction during Low-Intensity Resistance Exercise Increases S6K1 Phosphorylation and Muscle Protein Synthesis. J Appl Physiol 103:903-10, 2007
- Dillon EL, Volpi E, Wolfe RR, Sinha S, Sanford AP, Arrastia CD, Urban RJ, Casperson SL, Paddon-Jones D, and Sheffield-Moore M. Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy. Clin Nutr 26:736-743, 2007
- Dreyer HC, Drummond MJ, Fujita S, Glynn EL, Pennings B, Dhanani S, Volpi E, and Rasmussen BB. Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle. Am J Physiol Endocrinol Metab 294: E392-E400, 2008
- Drummond MJ, Fujita S, Takashi A, Dreyer HC, Volpi E, and Rasmussen BB. Human muscle gene expression following resistance exercise and blood flow restriction. Medicine and Science in Sports and Exercise 40:691-698 2008.
- Drummond, MJ, Dreyer HC, Pennings B, Fry CS, Dhanani S, Dillon EL, Sheffield-Moore M, Volpi E, and Rasmussen BB. Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging. J Appl Physiol, 104:1452-1461, 2008.
- Drummond MJ, Bell JA, Fujita S, Dreyer HC, Glynn EL, Volpi E, and Rasmussen BB. Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle. Clinical Nutrition 27(3):447-56, 2008
- Dreyer HC, Drummond MJ, Glynn EL, Fujita S, Chinkes DL, Volpi E, Rasmussen BB. Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery. J Appl Physiol 105(6):1967-74, 2008
- Volpi E, Chinkes DL, and Rasmussen BB. Sequential muscle biopsies during a six-hour tracer infusion do not affect human mixed muscle protein synthesis and muscle phenylalanine kinetics. Am J Physiol Endocrinol Metab 295(4):E959-63, 2008
- Drummond MJ, Miyazaki M, Dreyer HC, Pennings B, Dhanani S, Volpi E, Esser KA, and Rasmussen BB. Expression of growth-related genes in young and old human skeletal muscle following an acute stimulation of protein synthesis. J Appl Physiol, In Press [e-pub ahead of print September 2008]
- Fujita S, Dreyer HC, Drummond MJ, Glynn EL, Volpi E, and Rasmussen BB. Essential amino acid and carbohydrate ingestion prior to resistance exercise does not enhance post-exercise muscle protein synthesis. J Appl Physiol, In Press [e-Pub ahead of print, June 2008]
- Dillon EL, Janghorbani M, Angel JA, Casperson SL, Grady JJ, Urban RJ, Volpi E, Sheffield-Moore M. A novel non-invasive breath test method for screening persons at risk for diabetes. Diabetes Care, In press [e-pub ahead of print, December 2008]
- Drummond M.J., Fry CS, Glynn EL, Dreyer HC, Dhanani S, Timmerman KL, Volpi E, and Rasmussen BB. Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis. J Physiol, In Press [e-Pub ahead of print, Feb 2009]
The UTMB Center for Global Health Education (CGHE) is dedicated to the training of tomorrow's global health work force to improve health for the people of Texas and around the world. Check out their website for more information on the global health programs and education going on in our department.
The department of internal medicine is developing evidence based clinical protocols which will be available in EPIC (as order sets) for use when admitting patients with these diagnoses. Their AIM is to standardize care and decrease length of stay and readmission rates.Currently available protocols are:
- CAP - Community Acquired Pneumonia Orderset
- Congestive Heart Failure (CHF)
- Chronic Obstructive Pulmonary Disease (COPD)
- Diabetic Ketoacidosis Adult, ICU
- General Medicine Admission
- Immunodeficiency Flow Panel
- MICU/CCU Admission Order Set
- Oral Analgesic Medicaitons
- Parenteral Opioids
- Sepsis, Adult ICU
All protocols can be found in the EPIC order set section.
The department of Internal Medicine has a large role in the Meaningful Use Initiative. Our participation is key for the success of the initiative. Please visit the meaningful use website for important communication and updates from the Meaningful Use Initiative.