Alejandro Castellanos-Gonzalez, Ph.D
Molecular parasitology Research Instructor
Department of Internal Medicine
Division of Infectious Diseases
301 University Blvd, Marvin Graves Bldg., Rm 4.314-D
Galveston, Texas 77555-0435
|Degree/Training Completed||Year||Name & Location|
|B.S. Biology||2000||University National Autonomous of Mexico|
|M.S. Tropical Infectious Diseases||2002||University of Valencia, Spain|
|Ph.D. Biomedical Sciences||2005||University National Autonomous of Mexico|
|Postdoctoral Associate||2007||Baylor College of Medicine, Houston, Texas — Infectious Diseases|
|Postdoctoral Fellow||2009||University of Texas Medical Branch, Galveston, Texas — Infectious Diseases|
After completing my postdoctoral training at Baylor college of Medicine and UTMB I got a Jr. Faculty position as Instructor in the Division of infectious diseases at UTMB. I have several years of experience working in molecular parasitology. I'm co-investigator of the projects: "Point-of-care diagnostic tests for intestinal protozoa" funded for the Western Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research (WRCE) and Co-Investigator of the project "Calcium Dependent Protein Kinase 1 as a drug target for T. gondii and C. parvum" funded for the NIH/NIAID. Currently I'm responsible (PI) of the project: "Gene expression in human intestines in response to Cryptosporidium infection" funded for the Institute for Translational Sciences at UTMB. I'm member of the Center for Tropical Diseases (CTD) and the center Biodefense and Emerging Infectious Diseases (CBEID) and the Institute for Human Infections and Immunity at UTMB.
My interest is to study parasitic infections using molecular approaches as RNAi, miRNA, RNA-seq and Microarrays. The objective of my research is to understand how human cells respond against intestinal pathogens. The current goal at the lab is to standardize a system for long term-cultivation of human intestinal stem cells that could be used as a model to study Cryptosporidium infection, Our objective is to characterize the response of the human epithelial cells using molecular methods. We anticipate that the result of this research will lead in a better understanding of the host-Cryptosporidium relation that could allow the identification of novel targets needed for the development of vaccines and drugs.