3.0  Chemical Hygiene Plan

3.1  General Laboratory Safety Information

3.1.1  General Guidelines for Chemical Handling

3.1.2  Chemical Emergencies  Emergency Preparedness  First Aid Procedures  Spill Response Procedure  Fire Response Procedure

3.2  Laboratory-Specific CHP Elements

3.2.1  General Guidelines for Chemical Handling

3.2.2  Chemical Emergencies

3.2.3  Chemical Inventory and MSDSs

3.2.4  Laboratory-Specific Standard Operating Procedures (SOPs)

3.2.5  Training

3.0       Chemical Hygiene Plan (CHP)

A Chemical Hygiene Plan (CHP) is a written plan comprised of standard operating procedures (SOPs) for equipment (e.g., lab equipment, chemical fume hoods, biosafety cabinets, PPE), training, medical surveillance and work practices for protecting lab personnel from chemical and other hazards (e.g., biohazards, radioactive hazards).  This plan is typically divided into two section, general safety information and laboratory specific information.  The plan should be reviewed and updated as needed and at least annually.  The OSHA Lab Standard (29 CFR 1910.1450) requires development and implementation of a CHP.  While we are not subject to OSHA, other certifying bodies such as CAP and JCAHO require compliance with this requirement.


3.1       General Laboratory Safety Information

3.1.1       General Guidelines for Chemical Handling

The following are general guidelines for handling hazardous chemicals.  All personnel handling hazardous chemicals are responsible for knowing and following these general guidelines as well as any precautions that are specific to the chemicals with which they are working.  Additional information can be found in Chapter 7 of the Safety Manual, General Laboratory Safety.

·  Restrict access to hazardous chemicals to only authorized personnel.

· Ensure personnel handling hazardous chemicals have been trained in the hazards of the chemicals and precautions to take to protect themselves.

· Use the smallest amount and lowest concentration of chemical needed for the current task.

· Substitute less hazardous chemicals for more hazardous ones whenever possible.

· Work inside of a chemical fume hood when possible to minimize exposure.

· Wear all recommended PPE when working with hazardous chemicals.  Ensure lab coats are buttoned.  Ensure gloves selected are appropriate for the chemical.  Contact EHS B&C for assistance in selecting appropriate gloves.

· Dispose of all hazardous chemicals as directed by EHS Environmental Protection Management (EPM).  Do not pour hazardous chemicals down the drain.  Please see section 5.4 for more information on proper chemical disposal.

3.1.2       Chemical Emergencies       Emergency Preparedness

· Know the location of safety showers, eyewash stations, fire extinguishers and spill kits in each work area and how to use this equipment.

· Conduct procedures that involve hazardous chemicals or that may result in the production of aerosols, vapors or dangerous gases in a properly functioning chemical fume hood.

· Consider any unlabeled chemical hazardous until identified.

· Discard chemicals that have changed in color or appearance.

· Never work alone when conducting tests involving high risk hazardous chemicals.

· Ensure standard operating procedure as well as emergency (i.e., spill response, exposure) procedures are available in the work area.

· Ensure personnel are aware of exits and evacuation routes.       First Aid Procedures

· If chemical splashes in eyes, hold eyelids open and flush eyes with copious amounts of water for at least 20 minutes.

· If chemical contacts skin, wash thoroughly with soap and water.

· Report to the Employee Health Center if eye or skin contact with a chemical produces persistent pain after irrigation.

· Clean up any small chemical spills immediately and dispose of the waste material through EPM.       Spill Response Procedure

Clean up chemical spills promptly following the lab’s SOPs or instructions on the chemical MSDS.

· Small spills in a contained area (such as a chemical fume hood) or on absorbent material (such as a bench pad/diaper) can be cleaned up by lab personnel.

· Large spills require lab evacuation.  If the spill involves a flammable or combustible material, turn off any ignition sources as well.  After evacuation, contact EHS EPM for spill clean-up assistance.       Fire Response Procedure

· Ensure fire extinguishers appropriate for the chemicals in the work area are available.

· Ensure personnel are trained in extinguisher use. 

· If a fire occurs in a chemical fume hood, close the sash and call the fire department at extension 2-1211. 

· Review chemical MSDSs to determine if any special fire prevention/response procedures should be followed for a particular chemical. 

· Always practice R.A.C.E: Rescue and assist people, Alarm by notifying the fire dept., Confine the fire and close doors, Evacuate (or extinguish if trained).


3.2       Laboratory-Specific CHP Elements

3.2.1       Laboratory Contact Information

List key contacts for the laboratory including the building, room number, lab phone number, Principal Investigator name and phone number, Lab Contact(s) name(s) and phone number(s) and other personnel who work in the lab.  List any other rooms related to this lab including walk-in freezers/refrigerators, other storage locations and animal facilities.  This information should all be on the lab sign posted at the entrance.  To update the information or obtain a new lab sign, please contact EHS.

3.2.2       Laboratory-Specific Emergency Procedures

· Provide emergency contact information for key lab contacts (i.e., PI and Lab Contact home phone and mobile phone numbers).

· Provide a map or description of lab exits and evacuation routes.

· Provide emergency equipment locations (i.e., fire extinguishers, eyewash stations, safety showers, spill clean-up supplies/kits).

· Provide any special emergency information for hazardous materials used in the lab.

3.2.3       Chemical Inventory and MSDSs

Provide a chemical inventory for all hazardous chemicals used in the lab.  See section 2.3 for more information.  Include information on where to find MSDSs for the chemicals as well.

3.2.4       Laboratory-Specific Standard Operating Procedures (SOPs)

Develop and implement SOPs for lab equipment and hazardous materials including any materials or work requiring prior approval (e.g. High Risk Hazardous Chemicals, Select Agents, animal work).  Include any additional special equipment instructions, experimental procedures or precautions/procedures associated with unique hazards.  SOPs should include safe work practices (including storage conditions), exposure controls (i.e., use of chemical fume hoods, PPE), how to detect chemical presence or release, signs/symptoms of exposure, medical surveillance, waste disposal and spill response procedures. 

For materials designated as “Particularly Hazardous Substances” in the OSHA Lab Standard (i.e., carcinogens, reproductive toxins, chemicals with a high degree of acute toxicity or unknown toxicity), special control measures are required.  These materials must be handled in a “designated area”.  A designated area may be a chemical fume hood, specific area of a bench top or an entire lab.  The area must be labeled as a designated area and must be decontaminated after each use.  Spills of particularly hazardous substances must be cleaned up using wet vs. dry methods.  In addition, work surfaces should be covered with a disposable absorbent pad to contain small spills and aid in decontamination.  This information should be incorporated into specific SOPs for work with these substances.

3.2.5       Training

All lab personnel must be trained in the lab’s Chemical Hygiene Plan.  This training must be documented.  Training documentation must be provided to EHS B&C upon request during the annual Lab Audit.