Mission Statement 

The Synthetic Peptide Core produces peptides for a variety of applications utilizing solid-phase Fmoc chemistry and state-of-the-art automated synthesis instrumentation. This facility takes pride in producing highly purified peptides with minimal contaminants and sequence errors. Peptide homogeneity is routinely evaluated by mass analysis and analytical HPLC. Other assessment methods are also available.

Services Available

• FMOC automated solid-phase peptide synthesis
• Modifications of synthetic peptides
• Peptides for antibody production
  • Computer determined epitope design
• Preparative C18 RP-HPLC purification

Quality Control

• Analytical C18 RP-HPLC
• MALDI mass analysis (Mass Spectrometry Core)
• Edman peptide sequencing (Protein Chemistry Core)
• Amino acid compositional analysis (Protein Chemistry Core)

Major Equipment

• Applied Biosystems 433 Peptide Synthesizer
• Protein Technologies Symphony Multiple Peptide Synthesizer
  • Combinatorial peptide Synthesis Option
• Waters preparative LC Systems
• Vacuum drying equipment