Curriculum Vitae

NS 27910-19 RO1, “Mechanisms of Peripheral Analgesia: Group II mGluRs”, Susan M. Carlton, P.I. (8/1/04 -7/31/08), current year: $208,125 (direct costs).

NS 054765-02 RO1, “Peripheral Sensitization Following Spinal Cord Injury”, Susan M. Carlton, P.I. 08/01/07 – 07/31/12, $218,000 (direct costs).

NS 048777-02 R42, “Non-Peptide somatostatin Agonists Analgesics”, Susan M. Carlton, P.I. (09/01/06 – 08/31/08), $214,420/yr (direct costs).

P01 NS11255-32A2 Pain and Inflammation, Jin Mo Chung, Program Director. Project 4: "The Role of Reactive Oxygen Species in Central Neuropathic Pain", C. E. Hulsebosch, P.I. and S. M. Carlton Co-P.I. 04/01/08- 03/31/2013, $209,945/yr.

ARMY STTR A072-142-0602 “Gastrointestinal safe and potent anti-inflammatory drugs”, Upendra Marathi, P.I., S.M. Carlton, Co-P.I. 11/11/07 – 05/31/08, $100,000/yr.

Merck & Co. CON18266 “Localization of CGRP receptors using CRL-RAMP complex”, S.M. Carlton, P.I. 03/01/08-02/28/2009, $160,000

Frank A. Liddell fund of the Greater Houston Community Foundation, “Recovery of Pelvic Visceral function after SCI”, Claire E. Hulsebosch, P.I. (7/24/04 – open), $250,000. S.M.Carlton, Co-P.I., Subproject: Cytokine involvement in pressure sores. $50,000.

Carlton, S.M., Zhou, S., Du, J., Hargett, G. L., Ji, Guangchen, and Coggeshall, R.E, Somatostatin modulates the transient receptor potential vanilloid 1 (TRPV1) ion channel. Pain, 110:616-627, 2004.

Palecek, J., Neugebauer, V., Carlton, S.M., Iyengar, S., and Willis, W.D., The effect of kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates. Pain, 111:151-161, 2004.

Jimenez-Andrade, J. M., Zhou, S., Yamani, A., Valencia de Ita, S., Castaneda-Hernandez, G. and Carlton, S. M. Mechanisms by which peripheral galanin increases acute inflammatory pain. Brain Research,1056: 113-117, 2005.

Du, J., Zhou, S., and Carlton, S.M. Kainate-induced excitation of nociceptors in normal and inflamed rat glabrous skin. Neuroscience, 137:999-1013, 2006.

Ji, G., Zhou, S., Shapiro, G., Reubi, J.C., Jurczyk, S., Carlton, S.M., Analgesic activity of a non-peptide imidazolidinedione somatostatin agonist: in vitro and in vivo studies in rat. Pain, 124: 34-49, 2006.

Jimenez-Andrade, J.M., Lundstrom, L., Sollenberg, U.E., Langel, U., Castaneda-Hernandez, G., Carlton, S.M., Activation of peripheral galanin receptors: Differential effects on nociception. Pharm. Biochem. Behav., 85: 273-280, 2006.

Carlton, S.M., and Hargett, G.L. Co-localization of metabotropic glutamate receptors in rat dorsal root ganglion cells. J. Comp. Neurol., 501: 780-789, 2007.

Ji, G., Zhou, S. Kochukov, M., High, K.N. and Carlton, S.M., Plasticity in intact A-delta fibers contributes to cold hypersensitivity in neuropathic pain. Neuroscience, 150: 182-193, 2007.

Ji, G., Zhou, S. and Carlton, S.M., Intact Ad-fibers up-regulate TRPA1 and contribute to cold hypersensitivity in neuropathic rats. Neuroscience, 150: 1054-1066, 2008.

Du, J., Zhou, S. and Carlton, S.M., Group II metabotropic glutamate receptor activation attenuates peripheral sensitization in inflammatory states. Neuroscience, 154: 754-766, 2008.



CURRICULUM VITAE Current Grant Support NS 27910-19 RO1, “Mechanisms of Peripheral Analgesia: Group II mGluRs”, Susan M. Carlton, P.I. (8/1/04 -7/31/08), current year: $208,125 (direct costs). NS 054765-02 RO1, “Peripheral Sensitization Following Spinal Cord Injury”, Susan M. Carlton, P.I. 08/01/07 – 07/31/12, $218,000 (direct costs). NS 048777-02 R42, “Non-Peptide somatostatin Agonists Analgesics”, Susan M. Carlton, P.I. (09/01/06 – 08/31/08), $214,420/yr (direct costs). P01 NS11255-32A2 Pain and Inflammation, Jin Mo Chung, Program Director. Project 4: "The Role of Reactive Oxygen Species in Central Neuropathic Pain", C. E. Hulsebosch, P.I. and S. M. Carlton Co-P.I. 04/01/08- 03/31/2013, $209,945/yr. ARMY STTR A072-142-0602 “Gastrointestinal safe and potent anti-inflammatory drugs”, Upendra Marathi, P.I., S.M. Carlton, Co-P.I. 11/11/07 – 05/31/08, $100,000/yr. Merck & Co. CON18266 “Localization of CGRP receptors using CRL-RAMP complex”, S.M. Carlton, P.I. 03/01/08-02/28/2009, $160,000 Frank A. Liddell fund of the Greater Houston Community Foundation, “Recovery of Pelvic Visceral function after SCI”, Claire E. Hulsebosch, P.I. (7/24/04 – open), $250,000. S.M.Carlton, Co-P.I., Subproject: Cytokine involvement in pressure sores. $50,000. Selected Articles in Peer-Reviewed Journals (from 107) Carlton, S.M., Zhou, S., Du, J., Hargett, G. L., Ji, Guangchen, and Coggeshall, R.E, Somatostatin modulates the transient receptor potential vanilloid 1 (TRPV1) ion channel. Pain, 110:616-627, 2004. Palecek, J., Neugebauer, V., Carlton, S.M., Iyengar, S., and Willis, W.D., The effect of kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates. Pain, 111:151-161, 2004. Jimenez-Andrade, J. M., Zhou, S., Yamani, A., Valencia de Ita, S., Castaneda-Hernandez, G. and Carlton, S. M. Mechanisms by which peripheral galanin increases acute inflammatory pain. Brain Research,1056: 113-117, 2005. Du, J., Zhou, S., and Carlton, S.M. Kainate-induced excitation of nociceptors in normal and inflamed rat glabrous skin. Neuroscience, 137:999-1013, 2006. Ji, G., Zhou, S., Shapiro, G., Reubi, J.C., Jurczyk, S., Carlton, S.M., Analgesic activity of a non-peptide imidazolidinedione somatostatin agonist: in vitro and in vivo studies in rat. Pain, 124: 34-49, 2006. Jimenez-Andrade, J.M., Lundstrom, L., Sollenberg, U.E., Langel, U., Castaneda-Hernandez, G., Carlton, S.M., Activation of peripheral galanin receptors: Differential effects on nociception. Pharm. Biochem. Behav., 85: 273-280, 2006. Carlton, S.M., and Hargett, G.L. Co-localization of metabotropic glutamate receptors in rat dorsal root ganglion cells. J. Comp. Neurol., 501: 780-789, 2007. Ji, G., Zhou, S. Kochukov, M., High, K.N. and Carlton, S.M., Plasticity in intact A-delta fibers contributes to cold hypersensitivity in neuropathic pain. Neuroscience, 150: 182-193, 2007. Ji, G., Zhou, S. and Carlton, S.M., Intact Ad-fibers up-regulate TRPA1 and contribute to cold hypersensitivity in neuropathic rats. Neuroscience, 150: 1054-1066, 2008. Du, J., Zhou, S. and Carlton, S.M., Group II metabotropic glutamate receptor activation attenuates peripheral sensitization in inflammatory states. Neuroscience, 154: 754-766, 2008.