The Inhalation Toxicology Core (ITC) Facility is designed to provide state-of-the-art capabilities for conducting exposures of experimental animals and in vitro models to smoke, gas and vapor phase environmental toxicants. The facility operates under the auspices of the UTMB Sealy Center for Environmental Health and Medicine and is funded, in part, by UTMB institutional commitments. It serves as an institutional service core that provides support to all UTMB investigators and students. In addition, the facility provides a foundation for inter-institution collaborative investigations. The costs to investigators for performing exposures are based on offsetting expenses for facility personnel, equipment maintenance and replacement, animal husbandry, supplies, etc. All exposure protocols must be approved by the UTMB Chemical Safety Committee. If animals are involved, protocols must also receive prior Inter/Intra Institutional IACUC approval.
The Jaeger-Baumgartner Cigarette Smoking Machine (with Human Puff Profile Pump capability), is a fully automatic stand alone cigarette smoking device comprised of three main subassemblies, from top to bottom: the smoking machine, the electrical cabinet and a trolley with casters.
Also included is the autoloader with refillable 400+ cigarette capacity, power supply, rolling case and industrial computer unit with integrated display panel (Siemens). The table-top platen groups all mechanical components that are necessary to automatically smoke cigarettes in restricted smoking condition according to ISO 3308 standard.
The airway/lung physiology laboratories are comprised of a main lung function laboratory (284 ft2) and a large multi-functional laboratory (788 ft2), with an adjoining cell culture laboratory (291 ft2), complete with 4 cell culture hoods.
A new Scheduling Calendar link has been created at the top of the page so that investigators may plan their experiments when the facilities are available. To schedule a time slot for your experiments, e-mail your request to Request Scheduling.
If you have a need for additional protocols, please contact us at firstname.lastname@example.org so that we can plan them into a future update of the facility.