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 Last Modified: 11/07/03

 

Research on the GCRC

Principal Investigator

GCRC# / Title

Abdel-Rahman S

517 CYP2C9 Genotype and Long Term Warfarin Dose Requirements

Abdel-Rahman S

563 A Study of Cytogenetic Tests during Therapy with Methylphenidate

Abdel-Rahman S

612 Genetic Susceptibility to Tobacco Related Carcinogenesis

Anderson KE

399 Characterization of Enzyme Defects in Human Porphyrias

Anderson KE

548 Drug Safety in Acute Porphyrias

Anderson KE

682 Hydroxychloroquine vs. Phlebotomy for Porphyria Cutanea Tarda

Anderson KE

689 Genetic Susceptibility factors in Porphyria Cutanea Tarda

Ashizawa T

D156 A Placebo Controlled, Randomized, Double-Blind Phase II Clinical Trial to Evluate Tolerability, Safety and Efficacy Endpoints after Administration of Recombinant Human Insulin-like Growth Factor – I/Recombinant Human Insulin-like Growth Factor Binding Protein-3 (rhIGF-1GFBP-3) for 24 Weeks in Adults with Myotonic Dystrophy Type I

Berenson A

550 Effect of hormonal contraception on bone mineral density

Bessman J

681 Neuropsychological Dysfunction and Neuroimaging Abnormalities in Neurologically Intact Adult Patients with Sickle Cell Disease (SCD)

Blakeney P 510 Assisting the Transition of Pediatric Burn Survivors through Adolescence

Blakeney P

698 Outpatient Social Skills Training to Amplify Positive Gains for Distressed Adolescent Burn Survivors

Borsheim E

671 Transcapillary Insulin Transport & Aging

Borsheim E

632 Nutritional Supplementation and Insulin Resistance

Borsheim E

696 Effect of Amino Acid intake on VLDL Turnover

Borsheim E 

707 Visceral Fat Contribution to very Low Fat Density Lipoprotein (VLDL) – Triglyceride Synthesis in Women

Borsheim E  715 Amino Acid Supplementation in Recovery from Traumatic Brain Injury
Calhoun W 674 Severe Asthma Research Program (SARP)

Calhoun W

690 Macrolides in Asthma (MIA)

Chen J

647 Gastrointestinal Motor Functions in Patients with Systemic Sclerosis

Cunningham K

D157 A Human Laboratory Assessment of the Safety and Potential Efficacy of SYN117 (nepicastat) in Cocaine-dependent Volunteers Receiving Cocaine

Dreyer H

694 Exercise, Nutrition, and Sarcopenia in Older Adults

Dreyer H

706 Skeletal Muscle Metabolism and Total Knee Arthroplasty

Garofalo R

619 Study of Airway Inflammation by Proteomics Technologies in Children with RSV Infection

Garfield RE

500 Recording of Uterine Contractile Activity

Gelman B

631 CNS HIV Anti-Retroviral Therapy Effects Research (CHARTER)

Gonzalez E

D147 Controlled Randomized US Study of Nexalin for Temporary Reduction of Pain on Osteoarthritis

Grant A

668 Clinical Study to investigate the Efficacy and Safety of Purified C1 Esterase Inhibitor (Human) for the Treatment of Hereditary Angioedema (HAE) in Acute Attacks and as Prophylactic Treatment to Prevent HAE Attacks

Grant A

673 Randomized, Placebo-Controlled, Double-blind Phase II Study of the Safety and Efficacy of Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients with Hereditary Angioedema

Hankins G

650 Effects of Pregnancy on the Pharmacokinetics and Pharmacodynamics of Glyburide

Herndon D

645 Assessment on Anabolic Agents and Exercise in Burned Children

Islam J

667 The Role of Music Therapy in Alleviating Stress in Hip Surgery Patients

Jain S

702 Measurement of Growth Factors in cord Blood of Premature Infants to predict Necrotizing Enterocolitis

Khamapirad T

641 Clinical in vivo Evaluation of the Laser Optoacoustic Imaging System (LOIS) for Detection, Localization and Characterization of Breast Cancer

Killewich L

554 Peripheral Arterial Disease and Leg Muscle Metabolism

Kinsky M

677 The Effect of Beta-Adrenergic Agents on Fluid Therapy in Humans

Kinsky M

692 Modulating Fluid Therapy with Adrenergic Agents and Cyclic AMP Enhances in Humans

Klein GL

505 A Study of the Dynamics of Calcium and Collagen Accretion in Metabolically Normal Children undergoing Elective Orthopedic Surgery

Lau DT

623 An Open-Label Study Comparing the Efficacy of Pegasys and Ribavirin as Initial Treatment of Chronic Hepatitis C Between African-American and Caucasians

Lau DT

D138 Randomized, Open-label, Comparative Study to Evaluate Early Viral Load Reductions and Exploratory Viral Kinetics following Administration of Entecavir or Adefovir in Nucleoside-Naïve Adults with Chronic Hepatitis B Infections

Li H 709 The Longitudinal Study of Ocular Complications of AIDS

Lu LJ

533 Soybean Diet and Breast Density

Lu LJ

578 Comparative Hormonal Effects of Diets Containing Soy and Animal Protein

Lu LJ

633 Early Marker for Breast Cancer Risk in Nipple Aspirate Fluid

Lu LJ

635 Mammographic Density & Soy Isoflavones

McCauley M

656 Comparison of Mercury vs Aneroid Sphygmomanometer Blood Pressure Measurement in Human Subjects

McNearney T

485 Outcome in Systemic Sclerosis: Sociodemographic, …

Midoro-Huriuti

700 Studies of the Human Immune Response to Inhaled and Ingested Allergens

Moore M

629 A Phase I Trial Examining Skeletal Muscle Perfusion and Muscle Protein Metabolism in Healthy Elderly and Young Volunteers

Moore M

675 Noninvasive Assessment of Insulin Resistance: Phase I

Moore M

708 Muscle Perfusion and Protein Metabolism in Elderly

Moore M 713 Losartan as an Enhancer of Muscle Tissue Perfusion in Elderly: A Pilot Assessment of its Acute Vascular Effects

Nagamani M

546 Effect of Estrogen and Raloxifene on Insulin Sensitivity

O’Brien W

686 ACTG A5229: A Phase II/III, Randomized, Double-Blind, Placebo-Controlled Trial of Uridine Supplementation in HIV Lipoatrophy

O’Brien W

D150 A Phase III Randomized, Double-blinded, Placebo-controlled Trial to Investigate the Efficacy, Tolerability and Safety of TMC 125 as Part of an ART including TMC 114/RTV and an Investigator-Selected OBR in HIV-1 Infected Subjects with Limited to no Treatment Options

Paddon-Jones D

699 Restoration of Cell Signaling and Muscle Protein Synthesis in the Elderly

Powell D

642 Intestinal Myofibroblasts and Immune Tolerance

Petersen J

591 Identification of Novel Risk Factors in the Advancement of Peripheral Vascular Disease

Prough D

534 Optical Coherence Tomography for Non-invasive Glucose Sensing in Type 2 Diabetics and Healthy Subjects

Prough D

665 Novel Optoacoustic Monitoring System for Non-Invasive Measurement of Blood Oxygenation in Brain

Rasmussen B

649 Nutritional and Contractile Regulation of Muscle Growth

Rasmussen B

695 Essential Amino and Resistance Exercise in Aging

Rasmussen B 712 Effects of Resistance Exercise and Reduction of Blood Flow on Muscle Growth in Aging
Rasmussen B

D158 Carbohydrate vs Carbohydrate+protein Ingestion During Aerobic Exercise and the Impact on Skeletal Muscle Protein Synthesis during Exercise and Recovery

Reifsnider E 714 Reducing Overweight among Galveston WIC Participants

Rosenthal S

688 Seroprevalence and Prospective Risk Factor Analysis of Cytomegalovirus (CMV) Infections in Adolescent Males

Sahu G

701 Identification of Cellular Reservoirs for Residual Plasma HIV in Patients undergoing HAART

Sellin J

D155 A 24-month double-blind, randomized, multicenter, placebo controlled, parallel-group study comparing the efficacy and safety of 0.5 mg and 1.25 mg fingolimod (FTY720) administered orally once daily versus placebo in patients with relapsing-remitting multiple sclerosis

Smith G

D152 A 24-month double-blind, randomized, multicenter, placebo controlled, parallel-group study comparing the efficacy and safety of 0.5 mg and 1.25 mg fingolimod (FTY720) administered orally once daily versus placebo in patients with relapsing-remitting multiple sclerosis

Snyder N

595 Serum Markers of Fibrosis in Hepatitis C

Snyder N

D136 Open-Label, Efficacy Study of PegasysR Plus CopegusR in Treatment-Naïve Latino Patients with Chronic Hepatitis C-Genotype 1, as Compared to Treatment_naive Non-Latino Caucasian Patients with Chronic Hepatitis C

Snyder N

D153 A Multi-center, Randomized, Double-blind, Active-Control, 96 Week, Phase III Trial of the Efficacy and Safety of Clevudine Compared with Adefovir at weeks 48 and 96 in Nucleoside Treatment-Naïve Patients with HBeAg Negative Chronic Hepatitis due to Hepatitis B Virus

Snyder N

D154 A Multi-center, Randomized, Double-blind, Active-Control, 96 Week, Phase III Trial of the Efficacy and Safety of Clevudine Compared with Adefovir at weeks 48 and 96 in Nucleoside Treatment-Naïve Patients with HBeAg Positive Chronic Hepatitis due to Hepatitis B Virus

Snyder N

D159 A double-blind, randomized, placebo-controlled, parallel group study of rimonabant 20 mg daily for the treatment of non-diabetic patients with nonalcoholic steatohepatitis (NASH)

Snyder N

D160 A double-blind, randomized, placebo-controlled, parallel group study of rimonabant 20 mg daily for the treatment of Type 2 diabetic patients with nonalcoholic steatohepatitis (NASH)

Snyder N

D161 A phase 2a multi-center, randomized, controlled, single-blind dose ranging clinical study to evaluate the safety and antiviral effect of SCV07 in non-cirrhotic subjects with genotype 1 chronic hepatitis C who have relapsed to previous treatment

Sur S

703 Proteomic Technologies to Study Airway Inflammation

Svensen C

589 Evaluation of arterial and venous plasma dilution during bolus infusion of a crystalloid solution

Svensen C

664 The Effect of Isoflurane on Transcapillary Fluid Redistribution after Hemorrhage in Humans

Turley C

697 Evaluation of IMVAMUNE® Smallpox Vaccine with Respect to Safety and Optimization of Immune Responses by Administration Timing. Dose Level Administered, and Subsequent Boost with Dryvax® Smallpox Vaccine in Vaccinia-Naïve Adults

Turley C

704 A Single Center Double-Blind, Randomized, Escalating Dose-Ranging Study to Investigate the Safety and Immunogenicity of the VAX102 Influenza Vaccine in Healthy Adults

Urban R

615 The Effects of Cyclic Testosterone Administration in Older Individuals

Urban R

616 Anterior Pituitary Hormone Replacement in Traumatic Brain Injury

Volpi E

651 Skin Protein Turnover in Older Americans

Volpi E

653 Insulin and Sarcopenia in the Elderly

Volpi E

685 Insulin and Sarcopenia in the Elderly (Cycle No.2)

Volpi E

705 Nutritional Interventions for Maximal Muscle Gain in Middle-Aged, Trained Adults

Ware D / Meck J

655 NASA Bed Rest Campaign 3

Ware D

662 Encouraging and Studying the Effects of Exercise on Overweight Adolescents at Ball High School

Ware D

687 NASA Campaign 5 – Retention of Skeletal, Musculature and Postural Status with a Non-invasive, Extremely Low Level of Mechanical Signal: A Ground-Based Evaluation of Efficacy

Ware D 710 Feasibility Study of a Bedrest Analog for Lunar Exploration (JSC/UTMB)

Wolfe, RR

575 Insulin Resistance, Aging and their Relation to Muscle and Liver Lipid Content

Zwischenberger

462 Phase II Trial of Perfusion-Induced Systemic Hyperthermia for Advanced Loco-Regional or Metastatic Non-small Cell Lung Carcinoma