Jun Yang, Ph.D.
Instructor, Division of Endocrinology
Jun Yang, Ph.D.
Division of Endocrinology
Department of Internal Medicine
University of Texas Medical Branch
8.138 Medical Research Building
Galveston, Texas 77555-1060
NF-kB is one of the major signaling pathways triggered by inflammatory or infectious stimuli, whose activation temporally controls the induction of hundreds of genes, constituting the inflammatory transcriptome. Dr. Yang's research interest is to systematically reveal molecular mechanisms that underlie the selective activation of genes in response to activated NF-kB recruitment to chromatin. To this end, he recently has developed and applied a cutting edge technology of chromatin immunoprecipitation (ChIP) coupled with the next generation sequencing, known as ChIP-Seq, to identify NF-kB chromosome binding sites on the genome scale. Combined with genome-wide measurements of transcriptomes by RNA-Seq, Dr. Yang's study aims to link regulatory inputs with transcriptional outputs in NF-kB signal that mediates the innate immune response. Not only in basic medicine, this work also has a broad application in the field of translational research.
The department of internal medicine is developing evidence based clinical protocols which will be available in EPIC (as order sets) for use when admitting patients with these diagnoses. Their AIM is to standardize care and decrease length of stay and readmission rates.Currently available protocols are:
- CAP - Community Acquired Pneumonia Orderset
- Congestive Heart Failure (CHF)
- Chronic Obstructive Pulmonary Disease (COPD)
- Diabetic Ketoacidosis Adult, ICU
- General Medicine Admission
- Immunodeficiency Flow Panel
- MICU/CCU Admission Order Set
- Oral Analgesic Medicaitons
- Parenteral Opioids
- Sepsis, Adult ICU
All protocols can be found in the EPIC order set section.
The department of Internal Medicine has a large role in the Meaningful Use Initiative. Our participation is key for the success of the initiative. Please visit the meaningful use website for important communication and updates from the Meaningful Use Initiative.