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ALPHA-FETOPROTEIN, Maternal Serum (087-3750, 087-3744, 087-0041) Synonyms: AFP, Maternal Serum AFP, MS-AFP, Down's Syndrome screening, Triple Screen CPT 4 Codes: 82105, 84702, 82677 Limited Coverage Test NCD) Test Order Mnemonic: AFP-MS1 Test Includes: Downs Syndrome screening (AFP), Serum b-hCG and Estriol. Applies To: Screening test for neural tube defects (anencephaly, spina bifida) and Downs Syndrome of the fetus in pregnant women between 14 and 21 weeks gestation. For use as a tumor marker, see Alpha-Fetoprotein, serum. Lab: Clinical Chemistry Request Form: Routine Chemistry Form 2 Patient Preparation: Blood should be drawn before amniocentesis Collection: Routine venipuncture Storage Instructions: Keep samples refrigerated until delivered to laboratory. Causes for Rejection: Hemolysis Availability: Samples are accepted 24 hours per day at Sample Management, Room 5.136, McCullough. Turnaround Time: Routine: 48 hours. Samples delivered to the lab by 9 AM on Tuesdays and Thursdays are complete by 5 PM the same day. Special Instructions: In neural tube defect screening and Downs Syndrome screening, a Patient Information Form for AFP Testing which includes age, race, weight, insulin dependence, and gestation must be completed. Specimen: Blood Volume: 5 mL blood Minimum Volume: 0.6 mL serum Container: red-topped tube or gel separator tube (SST) Reference Ranges: For pregnancy ranges consult the laboratory Test Method: Chemiluminescence Revised April 2007 by P. Harris |
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