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DOXEPIN, serum (087-0587)

Synonyms: Sinequan

CPT 4 Code: 80166

Test Order Mnemonic: DOXEPIN

Test Includes: Desmethyldoxepin

Lab: Clinical Chemistry

Request Form: Special Chemistry Form 2

Collection: Routine venipuncture. The optimum time for collection of blood specimen is between 10 and 14 hours after the last dose of medication for patients taking antidepressants once a day and just before the morning dose for patients who are on a divided dose schedule. Request must include date and time of specimen collection.

Storage Instructions: Store at 2-8°C. Centrifuge the specimen and remove serum from the red cells within 4 hours of collection; freeze serum in plastic vial.

Causes for Rejection: Serum not separated from the clot in 4 hours or less, blood collected with plasticizers or gel separators/SST tubes

Availability: Samples are received 24 hours per day at Sample Management, 5.136 McCullough.

Turnaround Time: Routine: 3-5 days; test is performed on Tuesdays and Thursdays

Special Instructions: Blood specimens must arrive in the TDM laboratory before noon on the days of analysis to be included in the run.

Specimen: Blood

Volume: 7 mL blood

Minimum Volume: 1 mL serum

Container: Red-topped tube. Do not use SST tube.

Reference Ranges: Therapeutic Range: 150-250 ng/mL

Critical Values: Potential Toxicity: > 500 ng/mL

Test Method: HPLC

Reviewed/revised April 2007 by P. Harris

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