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QUAD SCREEN (087-0041), (087-3744), (087-3750), (087-3752)
Clinical Indication:

 Screening Test for Down Syndrome, Open Spina Bifida and Trisomy 18 risks in pregnant women
Test Mnemonic:

 Quad Scrn
Methodology:

 Chemiluminescense
Performed:

 Special Chemistry; Monday – Friday: 7 am – 3:30 pm     

Turnaround Time:

 M-F: within 24 hours

Specimen Requirements: Patient Preparation: Patient must be in the Second Trimester between 15 weeks, 0 days and 20 weeks, 6 days

Test includes:  Beta hCG, Unconjugated Estriol, Inhibin A and Alpha-fetoprotein (AFP)

Collect: Routine Venipuncture.  7mL of blood in SST.( Min.: 3mL of blood).

Specimen Preparation: Allow specimen to clot completely at room temperature. Centrifuge to separate serum from cells within 2 hours of collection. Transfer serum from collection tube to labeled plastic transport tube.   

 Storage/Transport:    Delivered to Sample Management within 2 hours of collection.  

Stability: Room temperature for ≤ 8 hours, refrigerated for ≤ 48 hours or frozen at -20°C or colder. (Avoid repeated freeze/thaw cycles).

Causes for Rejection:   Patient is less than or greater than the gestational age cutoff, incomplete and/or incorrect sample identification, improper storage/transport , and gross hemolysis or lipemia                                           
Reference Range:

By report (reports may vary based on instrumentation, patient age and sex)
Note:

 Please provide completed patient information sheet with sample.
CPT 4 Code:

 84702, 82105, 82677, 86336
Reviewed  Tho Nguyen MT(ASCP) 7/11/13

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient.  Components of the organ or disease panels may be ordered individually.  The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-9 code or its verbal equivalent.

 

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