CA-125, serum

Applies To: CA-125 is often elevated in active epithelial and other ovarian cancers. It may be elevated in benign disorders such as pericarditis, cirrhosis, severe endometriosis, first trimester of pregnancy, and ovarian cysts.

Lab: Clinical Chemistry

Request Form: Special Chemistry Form 2

Patient Preparation: Best to collect blood before a meal

Collection: Routine venipuncture

Storage Instructions: The sample should be refrigerated if not delivered to the lab promptly. Do not freeze the blood sample. Centrifuge the specimen, remove serum from red cells and refrigerate or freeze serum.

Causes for Rejection: Gross hemolysis

Availability: Samples are accepted 24 hours a day.

Turnaround Time: Test is performed Monday through Friday. 48 hour TAT. STAT testing available Monday through Friday 8am to 3pm per Physician request.

Specimen: Blood

Volume: 5 mL

Minimum Volume: 3 mL blood

Container: red-stoppered tube, SST vacutainer

Reference Ranges: Normal range is less than 21 U/mL

Test Method: Chemiluminescence

Reviewed/revised April 2007 by P. Harris

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