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Dilute Russell Viper Venom Test: (089-0526)

Clinical Indication:

Component of the Lupus Panel. DRVVT Check screens for Lupus-like anticoagulants (anti-phospholipid antibodies). DRVVT Check/Sure ratio confirms presence of Lupus Anticoagulants in plasma

Test Mnemonic:

 DRVVT

Methodology:

Screening test (DRVVT Check) is performed using the Electromechanical viscosity detection system. If result is >44.1 seconds, a second test is performed, this time with an excess of phospholipids to neutralize any remaining Lupus Anticoagulant (DRVVT Sure). The ratio Check /Sure is then calculated.
 

Performed:

Samples are accepted 24 hours per day at Sample Management, 5.136 McCullough Bldg.

Turnaround Time:

 7 days (call lab for schedule).

Specimen Requirements:

Collect:  Routine venipuncture; discard 1st mL of blood or collect other tubes (EDTA, red-topped) prior to collecting sample in blue-topped (citrate) tube.

Volume3.7 mL blood.(tube must be full)

 

Container:  3.2% Sodium citrate tube (light blue top tube)

Storage/Transport: Viable for 4 hours at room temperature.   If time from draw to receipt in the laboratory is to be greater than 4 hours, double centrifuge the specimen for 15 minutes at 1500g. Remove the plasma from red cells and snap freeze (-20°C) plasma.

Stability: Plasma  4 hrs at 2-4°C. Frozen plasma stored at -20 or below 6 months. Whole blood 4 hours at room temperature.

Causes for Rejection: QNS, clotted, severely hemolyzed, specimen greater than 4 hours old, wrong tube (3.8% sodium citrate), identification error, sample processed/transported and/or stored improperly.

Clinical Information:

If applicable, state clinical information that is required to be provided with specimen.

Reference Range:

DRVVT Check:   < 44.1 seconds = No significant evidence of Lupus Anticoagulant
DRVVT Check/Sure Ratio: < 1.2 = Negative (No significant evidence of Lupus Anticoagulant)

CPT 4 Code:

 85613

Reviewed: 3/27/2012

 A. Huerta, BS, MT(ASCP), MBA

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient.  Components of the organ or disease panels may be ordered individually.  The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-9 code or its verbal equivalent.

 

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