Laboratory Test Directory

Causes for Rejection: Improper collection, gross hemolysis. Specimen container unlabeled or labeled incorrectly. No date and time of collection on requisition form.

Clinical Information:

Reference Range:

Smith antibody is very specific for systemic lupus erythematosus (SLE) but only occurs in 30-35% of SLE cases. The presence of antibodies to Smith is often associated with renal disease.

RNP antibody is seen in 95-100 percent of mixed connective tissue disease and is considered specific for this syndrome if other antibodies are negative; RNP is also present in 20-30 percent of systemic lupus erythematosus and 15-25 percent of progressive systemic sclerosis.

Note:

This test is performed as a part of the ANA antibody test; call laboratory within 30 days for results (21125)

CPT 4 Code:

86235

Review

9/30/2013 by Theresa Friloux

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-9 code or its verbal equivalent.

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