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HEPATITIS B VIRUS SURFACE ANTIBODY (088-7201)

Synonyms: Antibody to Hepatitis B Surface Antigen, Anti-HBs, HbsAb

CPT 4 Code: 86706

Test Order Mnemonic: HBA

Lab: Serology

Request Form: Microbiology/Serology

Collection: Routine venipuncture, SST (serum separator tube)

Storage Instructions: Centrifuge the specimen and store at 2-8°C.

Causes for Rejection: Gross hemolysis, specimens containing particulate matter, heat-inactivated specimens

Availability: Samples are accepted 24 hours per day at Sample Management, 5.136 McCullough.

Turnaround Time: 24 - 72 hours

Special Instructions: This test is used to evaluate response to immunization and resolution of hepatitis disease. If the patient has no detectable antibody, it is recommended to wait three months before testing again. Tests on samples collected less than three months from the initial results will be cancelled, unless approved by a Microbiology Director or their designee. If "indeterminate", the assay is unable to determine if antibody to Hepatitis B surface antigen is present at levels consistent with immunity.  Patient's immune status should be assessed with other clinical information and/or retesting in 4-6 weeks if clinically indicated.

Recommended tests to determine acute hepatitis (see Note) are Hepatitis A virus antibody IgM, Hepatitis B Surface antigen, Hepatitis B Core antibody IgM and Hepatitis C virus antibody.
NOTE: Limited Coverage Test (NCD)

Recommended tests to determine chronic hepatitis are Hepatitis B Surface antigen, Hepatitis B Core antibody IgM and Hepatitis C virus antibody.

Specimen: Blood

Volume: 2ml serum

Container: SST (gel barrier)

Test Method: Enchanced chemiluminescence (ECi)

Revised/reviewed Feb. 2006 by T. Friloux

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