2015 IHII / McLaughlin Colloquium
on Infection & Immunity

Levin Hall Dining Room & North Auditorium
Friday, March 27 •  9:30 a.m. - 4:00 p.m.

This year's keynote lecture will take place in Levin Hall North Auditorium and the poster session will be held in Levin Hall Dining Room, where refreshments will be available all day.

AGENDA
8:30 - 9:30 Poster setup (presenters only)
9:30 - 12:15 Poster session
12:30 - 1:30 Keynote lecture
  Mary Estes, PhD
  "Human Intestinal Enteroids: Translating Stem Cell Biology to Understand Human Enteric Infection"
1:30 - 3 Poster session continues
3:30 Presentation of travel awards
3 - 4 Poster breakdown (any posters not removed by 4 p.m. will be discarded)
   
PROGRAM
GRADUATE STUDENTS
1 Jourdan Andersson HIGH-THROUGHPUT SCREENING OF NON-ANTIBIOTIC COMPOUNDS IN COMBATING PLAGUE CAUSED BY YERSINIA PESTIS
2 Sarah Auclair THERAPEUTIC EFFICACY OF A TCG2/TCG4 VACCINE IN CONTROLLING CHRONIC TRYPANOSOMA CRUZI INFECTION AND CHAGAS DISEASE IS ENHANCED BY GLUTATHIONE PEROXIDASE OVER-EXPRESSION
3 Jeremy Bechelli AUTOPHAGY SERVES AS A MECHANISM OF BACTERIAL KILLING DURING RICKETTSIA AUSTRALIS INFECTION.
4 Andrew Beck MASSIVELY PARALLEL SEQUENCING OF FRENCH NEUROTROPIC YELLOW FEVER VACCINE REVEALS A CONSERVED GENOTYPE AND DISSIMILARITY OF POPULATION STRUCTURE
5 Nicholas A. Bergren POTENTIAL EVOLUTIONARY INFLUENCES ON THE REDUCTION IN ENZOOTIC CIRCULATION AND HUMAN INCIDENCE OF WESTERN EQUINE ENCEPHALITIS 
6 Victor H. Carpio PROTECTIVE IL-10-PRODUCING TH1 CELLS ALSO MAKE IL-21, WHICH IS REGULATED BY IL-10 IN A MODEL OF CHRONIC MALARIA
7 Brian Dawes PRIMARY HUMAN NEURONAL STEM CELL DERIVED NEURON/ASTROCYTE CO-CULTURES TO STUDY LA CROSSE VIRUS INFECTION
8 Jesse Erasmus Development of Eilat Virus, a Host-Restricted Alphavirus, as a Vaccine Platform
9 Heather L Evans-Marin CCR9 REGULATES COLITIS DEVELOPMENT BY INHIBITING REGULATORY T CELL DEVELOPMENT
10 Tierra Farris EHRLICHIA CHAFFEENSIS TRP32 BINDS AN E-BOX-LIKE MOTIF AND INTERACTS WITH HOST GENES OF MAJOR CELLULAR PROCESSES
11 Eric Fitts NOVEL VIRULENCE FACTOR IN PLAGUE PATHOGENESIS
12 Tania Marlene Garron DEVELOPMENT OF HUMAN DIPEPTIDYL PEPTIDASE 4 (DPP4) TRANSGENIC MICE AS A ROBUST MODEL FOR STUDYING THE PATHOGENESIS AND SCREENING OF PREVENTIVE AND THERAPEUTIC MEASURES FOR MERS-COV INFECTION AND DISEASE
13 Julia Gerson TARGETING TOXIC TAU OLIGOMERS BY PASSIVE IMMUNOTHERAPY IN SYNUCLEINOPATHY MICE 
14 Steven Hallam TC83 REPLICON VACCINE CANDIDATE FOR LASSA AND MACHUPO VIRUSES
15 Christopher Lawrence Hatcher EVALUATING BURKHOLDERIA MALLEI TONB HCP1 MUTANT’S VACCINE POTENTIAL AGAINST RESPIRATORY GLANDERS.
16 Meghan Hermance IXODES SCAPULARIS SALIVA ENHANCES POWASSAN VIRUS TRANSMISSION TO THE HOST INFLUENCING ITS DISSEMINATION AND THE COURSE OF DISEASE 
17 Matthew Huante A SMALL ANIMAL MODEL OF IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME FOLLOWING ANTIRETROVIRAL THERAPY
18 Talha Ijaz CLODRONATE-LIPOSOMES DECREASE CIRCULATING MONOCYTES AND INHIBIT ANGIOTENSIN II- MEDIATED ASCENDING AORTIC DILATION
19 Tiffany Kautz AUTOCHTHONOUS TRANSMISSION OF CHIKUNGUNYA VIRUS DURING AN OUTBREAK OF FEBRILE ILLNESS IN CHIAPAS, MEXICO
20 Sue-Jie Koo MODULATION OF MACROPHAGE FUNCTION VIA METABOLISM BY TRYPANOSOMA CRUZI
21 Rose Langsjoen HOST PROTEIN DISULFIDE ISOMERASE REPRESENTS A NOVEL THERAPEUTIC TARGET FOR THE TREATMENT OF CHIKUNGUNYA VIRUS INFECTION
22 Hoai Jaclyn Ly DEVELOPMENT OF RIFT VALLEY FEVER VIRUS MP-12 VACCINE WITH SILENT MUTATION MARKERS FOR REASSORTMENT AND RECOMBINATION ANALYSES BETWEEN RVFV STRAINS 
23 Tyler Manning MECHANISMS OF JUNIN VIRUS ATTENUATION
24 Alexander McAuley GENERATION AND CHARACTERISATION OF FLAVIVIRUS RECEPTOR-BINDING DOMAIN CHIMAERAS
25 Audrie Ann Medina CD4 T CELLS IN THE PATHOGENESIS OF VISCERAL LEISHMANIASIS
26 Laura Muruato IDENTIFICATION OF NOVEL BURKHOLDERIA VACCINE CANDIDATES USING BIO- AND IMMUNO-INFORMATIC APPROACHES
27 Samantha Nava RNA INTERFERENCE COMPLEXES: A NOVEL METHOD TO GENE SILENCING IN CRYPTOSPORIDIUM
28 Tomoki Nishiguchi RESISTANCE OF SUBACUTELY BURNED MICE THERAPEUTICALLY TREATED WITH CCL1 ANTISENSE OLIGODEOXYNUCLEOTIDE AGAINST INFECTIONS WITH MRSA OR E. FAECALIS.
29 Rebecca J. Nusbaum HIV-1 PROMOTES NEUTROPHIL INFILTRATION AND LUNG DAMAGE IN HUMANIZED MICE CO-INFECTED WITH MYCOBACTERIUM TUBERCULOSIS
30 Inaia Phoenix ABOLISHMENT OF RIFT VALLEY FEVER VIRUS GN/GC N-GLYCOSYLATION SITES ALTERS INFECTIVITY VIA DC-SIGN 
31 Sergio E Rodriguez DEVELOPING RECOMBINANT VESICULAR STOMATITIS VIRUSES TO STUDY GLYCOPROTEINS OF A TICK-BORNE HEMORRHAGIC FEVER VIRUS
32 Shannon Ronca EVALUATING BEHAVIORAL CHANGES FOLLOWING ALPHAVIRUS INFECTION IN MICE
33 Brittany N. Ross E. COLI O104:H4 LONG POLAR FIMBRIAE ROLE IN COLONIZATION AND BIOFILM FORMATION
34 Benjamin Ari Satterfield CONTRIBUTIONS OF THE NIPAH VIRUS C AND W PROTEINS TO PATHOGENESIS IN THE FERRET MODEL
35 Casey L. C. Schroeder IDENTIFICATION AND VALIDATION OF SMALL, NONCODING RNAS IN RICKETTSIA PROWAZEKII
36 Jesus A. Silvas SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME VIRUS INFECTION INDUCES THE SECRETION OF EXTRACELLULAR MICROVESICLES
37 Claire Smalley ACTIVATION KINETICS OF INFLAMMASOME BY RICKETTSIAE IN MURINE MACROPHAGES
38 Daniele Swetnam MIGRATION AND EVOLUTION OF WEST NILE VIRUS IN THE US
39 Bethany Tiner TRIPLE DELETION OF MEMBRANE PROTEIN-ENCODING GENES HIGHLY ATTENUATES YERSINIA PESTIS CO92: DEVELOPMENT OF A POTENTIAL LIVE-ATTENUATED PLAGUE VACCINE 
40 Stephanie P. Vega DEVELOPMENT OF HUMAN  LUNG MODEL TO STUDY PATHOGENESIS OF LUNG DISEASE 
41 Xianxiu Wan Enhancing SIRT1/PGC-1α activity improves heart function through activating mitochondrial biogenesis and inhibiting inflammatory pathways in Chagas disease
42 Jia Wang HUMAN PAPILLOMAVIRUS TYPE 11 E6 INTERACTS WITH STERILE ALPHA MOTIF DOMAIN CONTAINING 9 
43 Stephan Patrick Willias NOVEL INSIGHT INTO YERSINIA PESTIS PATHOGENESIS THROUGH CHARACTERIZATION OF THE CARBON STORAGE REGULATOR PROTEIN, CSRA
44 Kyle Wilson DECREASED ANIMAL BEHAVIOR AND ALTERED CELLULAR PROFILE IN BRAINS OF IL-10-DEFICIENT MICE INFECTED WITH PLASMODIUM CHABAUDI CHABAUDI (AS)
45 Wei Wu COMMENSAL FLAGELLATED A4 INHIBIT INTESTINAL TH2 RESPONSES THROUGH INDUCTION OF INNATE CELL TGFB PRODUCTION
46 Guang Xu INVESTIGATION OF HOST IMMUNITY DURING ORIENTIA TSUTSUGAMUSHI INFECTION
POSTDOCTORAL FELLOWS
47 Albert Auguste CHARACTERISTICS OF A HOST RESTRICTED FLAVIVIRUS
48 Anthony Cao INTESTINAL TH17 CELS REINFORCE EPITHELIAL INTEGRITY BY PRODUCTION OF AMPHIREGULIN
49 Yu Chen MAVS plays an essential role in host immunity against human metapneumovirus 
50 Nilay Dey CASPASE-1/ASC INFLAMMASOME- MEDIATED ACTIVATION OF IL-1b–ROS–NF-kB PATHWAY FOR CONTROL OF TRYPANOSOMA CRUZI REPLICATION AND SURVIVAL IS DISPENSABLE IN NLRP3-/- MACROPHAGES
51 Gillian Eastwood Enzootic Transmission and Ecology of Arboviruses in Sylvatic regions of Kenya
52 Mark A. Endsley THE INTRACELLULAR DOMAIN OF ADAM10 BINDS HIV-1 INTEGRASE TO FACILITATE NUCLEAR TRAFFICKING OF THE PRE-INTEGRATION COMPLEX
53 Olivier Escaffre THE EFFECT OF NIPAH VIRUS INDUCED OXIDATIVE STRESS ON THE IMMUNE RESPONSE IN HUMAN AIRWAY EPITHELIAL CELLS
54 Brian Friedrich EFFECTS OF ATTENUATING AND COMPENSATORY MUTATIONS IN THE PUTATIVE RECEPTOR BINDING DOMAIN OF WEST NILE VIRUS ENVELOPE PROTEIN ON ANTIGENICITY AND NEUTRALIZATION
55 Fangjian Guo COMPARISON OF HPV PREVALENCE BETWEEN HPV-VACCINATED AND NON-VACCINATED YOUNG ADULT WOMEN (20-26 YEARS)
56 Terence Hill CONTRIBUTION OF TYPE II INTERFERON TO THE MANIFESTATION OF PULMONARY DISEASE IN THE NIPAH VIRUS MURINE MODEL
57 Jia Hu IDENTIFICATION OF THE REGULATOR CONTROLLING LPF EXPRESSION IN ENTEROPATHOGENIC ESCHERICHIA COLI
58 Cheng Huang DISTINCT HOST INNATE IMMUNE RESPONSES TO HIGHLY PATHOGENIC NEW WORLD AND OLD WORLD HUMAN ARENAVIRUSES
59 Samad Ibitokou MEMORY CD4 T CELL ACTIVATION IN CHRONIC MALARIA INFECTION
60 Ichiaki Ito THE REVERSION OF M2B MONOCYTES IN CULTURES OF BURN PATIENT MONOCYTES TREATED WITH A SELECTED HUMAN CCL1 ANTISENSE OLIGODEOXYNUCLEOTIDE
61 Valerie Klema FULL-LENGTH DENGUE VIRUS NONSTRUCTURAL PROTEIN 5 (NS5) ASSEMBLES INTO A DIMER WITH A UNIQUE METHYLTRANSFERASE AND POLYMERASE INTERFACE
62 Takaaki Koma DEVELOPMENT OF RECOMBINANT VACCINES AGAINST MACHUPO VIRUS
63 Yuejin Liang IL-33 MODULATES INNATE CELL RESPONSE AND PROMOTES IFN-g PRODUCTION IN VIRAL HEPATITIS
64 Huanle Luo A WEST NILE VIRUS NS4B P38G MUTANT INDUCES MAVS-DEPENDENT TYPE 1 INTERFERON AND THE HOST ANTI-VIRAL RESPONSES
65 Keisuke Nakagawa MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS NSP1 EMPLOYS A NOVEL MECHANISM TO SELECTIVELY INHIBIT HOST GENE EXPRESSION
66 Hema P Narra LITTLE BUT IMPORTANT: NOVEL SMALL REGULATORY RNAs IN RICKETTSIA CONORII
67 Shoko Nishiyama  L-segment mutations are responsible for temperature-sensitivity of Rift Valley fever MP-12 vaccine
68 Michael M. Opata DECREASING INITIAL STIMULATION INCREASES GENERATION OF EARLY EFFECTOR CELLS THAT SURVIVE THE CONTRACTION PHASE IN MALARIA INFECTION
69 Elvia Janeth Osorio REDUCED FREQUENCY AND ALTERED MIGRATION OF DENDRITIC CELLS IN MALNUTRITION CONTRIBUTES TO VISCERALIZATION OF THE INTRACELLULAR PATHOGEN LEISHMANIA DONOVANI 
70 Alex Peniche EFFECT OF AGE ON CLOSTRIDIUM DIFFICILE INFECTION IN A MURINE MODEL OF INFECTION
71 Duraisamy Ponnusamy HIGH-THROUGHPUT SIGNATURE-TAGGED MUTAGENIC APPROACH TO IDENTIFY NOVEL VIRULENCE FACTORS OF YERSINIA PESTIS CO92 IN A MOUSE MODEL OF INFECTION
72 Valentina Reffatto EXOSOMES AS A NOVEL IMMUNOMODULATORY MECHANISM FOR CHRONIC EYE INFLAMMATION. 
73 Kimberly Roberts OROPOUCHE VIRUS INFECTION IN HUMAN ENDOTHELIAL AND NEURONAL CELLS
74 Omar Saldarriaga  DEVELOPMENT OF A POINT-OF-CARE MOLECULAR TEST FOR AMERICAN CUTANEOUS LEISHMANIASIS
75 Omar Saldarriaga TRANSCRIPTOME ANALYSIS OF HUMAN VISCERAL LEISHMANIASIS: EXPLORING IMMUNOREGULATORY NETWORKS AND IMMUNOPATHOGENIC PATHWAYS
76 Vanessa V Sarathy COMPARISON OF SYSTEMIC DISEASE BETWEEN TWO GENOTYPE II DENGUE VIRUS TYPE 3 STRAINS IN AG129 MICE
77 Saravanabalaji Shanmugam Hepatitis C Virus (HCV) NS5A dimerizes via at least two different interfaces in cells
78 Thomas R. Shelite IL-33 IN RENAL PATHOLOGY AND ENDOTHELIAL DAMAGE DURING ORIENTIA-INFECTION
79 Han Xia NEXT GENERATION SEQUENCING REVEALS HIGH POPULATION DIVERISTY OF CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS IN ITS TICK VECTOR 
CLINICAL FELLOW
80 Karel Capek HERPESVIRIDAE VIREMIA IN PEDIATRIC BURN PATIENTS

Institute for Human Infections & Immunity