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Current MD-PhD Student - Eric Carlsen

Eric Carlsen

Name: Eric Carlsen

Year in Program: GY3

Undergrad University: Ohio University

Mentor: Lynn Soong, M.D., Ph.D.

Graduate Program: Microbiology/Immunology

   

    Research Interests

  • Inate immunity

    Honors & Awards

  • Ohio University Founder's Award, 2004-2008
  • Ohio University Tropical Disease Institute Travel Grant for Research in Rural Ecuador, June 2007
  • Dr. Ruth Mathewson Award, Ohio University, 2008
  • UTMB Fogarty Fellowship for Research in Lima, Peru, June 2009
  • T32 Training Grant in Emerging and Infectious Tropical Disease, September 2010
  • David and Janet Niesel Scholarship Award, 2010
  • Robert Bennet Tuition Scholarship Award, 2011

    Publications

  • Wang Y, Chen Y, Xin L, Beverley SM, Carlsen ED, Popov V, Chang KP, Wang M, Soong L. Differential micobicidal effects of human histone proteins H2A and H2B on Leishmania promastigotes and amastigotes. Infect Immun. 2011. 79(3):1124-33.
  • Carlsen ED, Hay C, Henard CA, Popov V, Garg NJ, Soong L. Leishmania amazonensis amastigotes trigger neutrophil activation, but resist neutrophil microbicidal mechanisms. Under review, Infect Immun.
  • Aguilar-Valenzuela R, Carlsen ED, Liang Y, Soong L, Sun J. Hepatocyte Growth Factor Dampens Liver Immune- Mediated Pathology in Acute Viral Hepatitis without Compromising Antiviral Activity. J Gastroenterol Hepatol. In revision.
  • Henard CA, Carlsen ED, Hay C, Wang H, Kima P, Soong L. Leishmania amazonensis amastigotes secrete a stage-specific peroxidase in response to nitrogen oxides that fosters intracellular parasite survival. PLoS Pathogens. In preparation.
  • Eaves-Pyles S, Patel J, Arigi E, Cong Y, Cao A, Garg NJ, Dhiman M, Pyles R, Arulanandam B, Miller A, Popov VL, Soong L, Carlsen ED, Coletta C, Szabo C, Almeida I. Immunomodulatory and anti-bacterial effects of cystatin-9 against F. tularensis. Cell Host & Microbe. In preparation.

    Presentations

  • Vargas-Inchaustegui DA, Carlsen E, Espinosa D, Tulliano G, Pacheco R, Llanos-Cuentas A, Arevalo J, and Soong L. The expression of inflammatory mediators and its association with the susceptibility to mucosal leishmaniasis in Peru. Presented at the IHII/McLaughlin Colloquium, UTMB, 2009
  • Vargas-Inchaustegui DA, Carlsen E, Espinosa D, Tulliano G, Pacheco R, Llanos-Cuentas A, Arevalo J, and Soong L. The expression of inflammatory mediators and its association with the susceptibility to mucosal leishmaniasis in Peru. Presented at the National Student Research Forum, UTMB, 2009
  • ED Carlsen, CL Hay, Y Liang, C Yang, J Sun, L Soong. Enhanced leishmaniasis pathogenesis through type I interferon signaling. Presented at the IHII/McLaughlin Colloquium, UTMB, 2012

    Hobbies or just something about yourself in general:

  • I enjoy cycling, swimming, cooking, bluegrass, and playing bass in local rock and blues/jazz bands.

Career Development

The career development of an MD-PhD student is critically important and extends out well past the date of graduation with the dual degrees. The UTMB MD-PhD Program carefully guides and nurtures students throughout the Program. Early in the Program, critical issues are mentor selection and choice of a graduate program. MD-PhD students meet regularly with a faculty advisor, a student "big sibling" and members of the advisory committee. Opportunities to be exposed to research opportunities are provided through Program activities as well as the scientific activities on campus. Most students do their initial laboratory rotation during the summer before starting medical school. Additional laboratory rotations can be completed during the summer before the first and second years of medical school and after the second year of medical school. Once students are established in their labs, they are guided through their research by a mentor and dissertation committee.

For MD-PhD students, selection of the dissertation committee is essential and our Program requires students to include a member who is an MD scientist who can provide guidance on career progress and residency selections. As thesis defense approaches, students design their optimal clinical experiences with members of the MD-PhD committee to maximize chances to obtain the types of residency training that will be most compatible with further development as a physician scientist. The Program runs career guidance seminars to alert students to many of the important issues, pitfalls and milestones that they will need to navigate in the future. These include the pros and cons of short-track residencies, the need for additional postdoctoral training, and how to select and negotiate a first faculty appointment. The UTMB MD-PhD graduate is thus well positioned to make the most out of the advantages that MD-PhD careers offer.