NCB - The Department of Neuroscience and Cell Biology

Publications

Recent Publications

Bhat, K. M., Gaziova, I., Katipalla, S. (2011). Neuralized mediates asymmetric division of neural precursors by two distinct and sequential events: promoting asymmetric localization of Numb and enhancing activation of Notch-signaling. Dev. Biol. 351: 186–198.

Zhu, Z and Bhat, K. M. (2011). The Drosophila Hem protein regulates asymmetric division upstream of Notch via regulating Inscuteable localization. Mech Dev. 128:483-95..

Zhu, Z., and Bhat, K. M. (2011). The Drosophila Hem/Kette/Nap1 protein regulates asymmetric division of neural precursor cells by regulating localization of Inscuteable and Numb. Dev. Biol. 357: 283-294.

Hafer, N., Xu, S., Bhat, K. M., and Schedl, P. (2011). The Drosophila CPEB Protein Orb2 Has a Novel Expression Pattern and is Important for Asymmetric Cell Division and Nervous System Function. Genetics 189: 907-21.

Gaziova, I., and Bhat, K. M. (2009). Ancestry-independent fate specification and plasticity in the developmental timing of a typical Drosophila neuronal lineage. Development 136: 263-274.

Gazi, M., Shyamala, B. V., and Bhat, K. M. (2009). The tumor suppressor protein Patched regulates synaptic connections via cholesterol in the adult brain and suppresses a neural disease in Drosophila. Dev. Biol. 334: 311-323.

Bhat, K. M., Gaziova, I., Krishnan, S. (2007). Regulation of Axon guidance by Slit and Netrin signaling in the Drosophila ventral nerve cord. Genetics 176: 2235-2246.

Bhat, K. M. (2007). Neuronal migratory pattern is determined at the precursor cell stage and is necessary for the proper axon projection in the Drosophila nerve cord. Develop. Biol. 311: 613-622.

Merianda, T. T., and Bhat, K. M. (2005). Requirement of Patched reveals the role of pioneering neurons for the guidance of medial longitudinal tracts in the Drosophila ventral nerve cord. Dev. Genes Evoln. 215: 285-296.

Bhat, K. M. (2005). The primary role of Slit during the positioning of longitudinal tracts in the Drosophila nerve cord is to silence Netrin-mediated attraction. Genetics 170: 149-159.

Bhat, K. M., and Apsel, N. (2004). Upregulation of Mitimere and Nubbin acts through CyclinE to confer self-renewing asymmetric division potential to neural precursor cells. Development 131: 1123-1134.

Yedvobnick, B., Kumar, A., Opraseuth, J., Mortimer, N., and Bhat, K. M. (2004). The asymmetric division function of Mastermind is separable and distinct from its neurogenic function during Drosophila neurogenesis. Genetics 166:1281-1289.

Shyamala, B. V., and Bhat, K. M. (2002). A Hedgehog independent Patched-Smoothened signaling activates Baboon/Activin pathway to regulate head morphogenesis in Drosophila. Development 129: 1839-1847.

Mehta, B., and Bhat, K. M. (2001). Slit mediated signaling regulates the asymmetric localization of Inscuteable and promotes the terminal asymmetric division of secondary neuronal precursor cells in the Drosophila CNS. Development 128: 3161-3168.

Bhat, K. M., Van Beers, E., and Bhat, P. (2000). sloppy paired acts as the downstream target of Wingless in the Drosophila CNS and interaction between sloppy paired and gooseberry inhibits sloppy paired during neurogenesis. Development 127: 655-665.

Wai, P., Truong, B., and Bhat, K. M. (1999). Cell division genes promote asymmetric localization of determinants and interaction between Numb and Notch in the Drosophila CNS. Development 126: 2759-2770.

Bhat, K. M. (1999). The posterior determinant Nanos is required for the maintenance of adult germline stem cells during Drosophila oogenesis. Genetics 151: 1479-1492.

Bhat, K. M. (1999). Segmental genes and neuroblast specification and lineage elaboration in Drosophila. BioEssays 21: 472-485.

Bhat, K. M. (1998). frizzled and frizzled 2 play a partially redundant role in the Wingless signaling pathway and have similar functions to Wingless in neurogenesis. Cell 95: 1027-1036.