Miguel A. Pappolla, M.D., Ph.D.

Professor

Division/ Program Title:

Department of Neurology

Mailing Address:

301 University Blvd, Route 0539
Galveston, TX 77555-0539

Office:

2646 S. Loop W. Ste 106

Phone:

713-661-0300

Fax:

281-822-0480

Education and Post Graduate Training:

 

  • Medical School
    University of Buenos Aires, Argentina (1978)
  • Residency: Anatomic and Pathology
    Northeastern Ohio Universities, July 1980-June 1983
  • Fellowship: Neuropathology
    Case Western Reserve University, July 1983-June 1984
  • Fellowship: Neuropathology
    Cleveland Clinic Foundation, July 1984-June 1985
  • Residency: Neurology
    University of South Alabama, October 1996-September 2000
  • Fellowship: Interventional Pain Management
    (Anesthesia accredited program)
    University of Mississippi, Jackson Mississippi (2005-2006)
  • PhD-Doctorate
    University of Catalunya, Barcelona, Spain (2002)
  • Link to CV

Board Certifications:

  • Board Certified and Diplomate in Neurology
  • Board Certified and fellowship trained in Pain Medicine
  • Board Certified in Anatomic and Clinical Pathology
  • Board Certified and fellowship trained in Neuropatholy

Specialties:

  • Neurology and Pain Management

Clinical Interest:

  • Neuropathology
  • Interventional Pain Management

Research Interest:

  • Alzheimer's Disease

Selected Publications:

  • Barnwell E, Padmaraju V, Baranello R, Pacheco-Quinto J, Crosson C, Ablonczy Z, Eckman E, Eckman CB, Ramakrishnan V, Greig NH, Pappolla MA, Sambamurti K. Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein. PLoS One. 2014 Mar 21;9(3):91531.
  • Pinnix I, Ghiso JA, Pappolla MA, Sambamurti K. Major carboxyl terminal fragments generated by γ-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long. Am J Geriatr Psychiatry. 2013 May;21(5):474-83.
  • Sambamurti K, Greig NH, Utsuki T, Barnwell EL, Sharma E, Mazell C, Bhat NR, Kindy MS, Lahiri DK, Pappolla MA. Targets for AD treatment: conflicting messages from γ-secretase inhibitors. J Neurochem. 2011 May;117(3):359-74.

Honors and Awards:

  • Most Compassionate Doctor Award 2013