Yogi Wairkar, Ph.D.

Assistant Professor

Division/ Program Title:

Mitchell Center for Neurodegenerative Disorders,
Department of Neurology

Mailing Address:

301 University Blvd, Route 1045
Galveston, TX 77555-1045

Office:

Medical Research Building, Room 10.138B

Phone:

(409) 772-8212

Fax:

(409) 747-0015

Education and Post Graduate Training:

  • Ph.D., University of Cambridge, Cambridge, UK
  • Postdoctoral Training, Washington University Medical School, St. Louis, MO
  • Link to CV

Board Certifications:

  • N/A

Specialties:

  • N/A

Clinical Interest:

  • N/A

Research Interest:

  • Neurodevelopment and Neurodegeneration

Selected Publications:

Tuberous sclerosis complex regulates Drosophila neuromuscular junction growth via the TORC2/Akt pathway.

Natarajan R, Trivedi-Vyas D, Wairkar YP.
Hum Mol Genet. 2013 May 15;22(10):2010-23. doi: 10.1093/hmg/ddt053. Epub 2013 Feb 7. PMID: 23393158

Identification of potential mediators of retinotopic mapping: a comparative proteomic analysis of optic nerve from WT and Phr1 retinal knockout mice.

Lee AR, Lamb RR, Chang JH, Erdmann-Gilmore P, Lichti CF, Rohrs HW, Malone JP, Wairkar YP, DiAntonio A, Townsend RR, Culican SM.
J Proteome Res. 2012 Nov 2;11(11):5515-26. doi: 10.1021/pr300767a. Epub 2012 Oct 23. PMID: 22985349

The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation.

Kim S*, Wairkar YP*, Daniels RW, DiAntonio A.
J Cell Biol. 2010 Mar 8;188(5):717-34. doi: 10.1083/jcb.200911126. Epub 2010 Mar 1. PMID: 20194640
* Equal Contribution.

Unc-51 controls active zone density and protein composition by downregulating ERK signaling.
Wairkar YP, Toda H, Mochizuki H, Furukubo-Tokunaga K, Tomoda T, Diantonio A.
J Neurosci. 2009 Jan 14;29(2):517-28. doi: 10.1523/JNEUROSCI.3848-08.2009. PMID:19144852

Synaptic defects in a Drosophila model of congenital muscular dystrophy.

Wairkar YP
, Fradkin LG, Noordermeer JN, DiAntonio A.
J Neurosci. 2008 Apr 2;28(14):3781-9. doi: 10.1523/JNEUROSCI.0478-

Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development.
Koh TW, Korolchuk VI, Wairkar YP, Jiao W, Evergren E, Pan H, Zhou Y, Venken KJ, Shupliakov O, Robinson IM, O'Kane CJ, Bellen HJ.
J Cell Biol. 2007 Jul 16;178(2):309-22. Epub 2007 Jul 9.

The B' protein phosphatase 2A regulatory subunit well-rounded regulates synaptic growth and cytoskeletal stability at the Drosophila neuromuscular junction.

Viquez NM, Li CR, Wairkar YP, DiAntonio A.
J Neurosci. 2006 Sep 6;26(36):9293-303.PMID:16957085

Highwire restrains synaptic growth by attenuating a MAP kinase signal.
Collins CA, Wairkar YP, Johnson SL, DiAntonio A.
Neuron. 2006 Jul 6;51(1):57-69.PMID:16815332

Highwire function at the Drosophila neuromuscular junction: spatial, structural, and temporal requirements.

Wu C, Wairkar YP, Collins CA, DiAntonio A.
J Neurosci. 2005 Oct 19;25(42):9557-66. PMID:16237161

Honors and Awards:

  • Cambridge Commonwealth Trust Award (Ph.D.)
  • STARS Award (University of Texas System).

Professional Affiliations:

Society for Neuroscience

Link

http://www.utmb.edu/neuro/research/flylab/default.asp