UTMB researchers have discovered that hydrogen sulfide — the pungent-smelling gas produced by rotten eggs — is a key player in colon cancer metabolism, and a potential target for therapies for the disease. In a paper appearing online this week in the Proceedings of the National Academy of Sciences, the UTMB scientists describe cell-culture and mouse experiments demonstrating that colon cancer cells produce large amounts of hydrogen sulfide, and depend on the compound for survival and growth. “They love it and they need it,” said UTMB professor Dr. Csaba Szabo, an author on the paper. “Colon cancer cells thrive on this stuff — our data show that they use it to make energy, to divide, to grow and to invade the host.” The news also appears in the Business Standard, Science Daily, BioPortfolio and the Times of India.