Business Standard March 20, 2014
Researchers have discovered a new method that may halt the progression of dementia caused by accumulation of a protein known as tau. Normally, tau protein is involved in microtubule formation, which acts as a brain cell's transportation system for carrying nutrients in and waste out. In the absence of tau protein, brain cells become dysfunctional and eventually die, said researchers at UTMB. "This is significant because this research describes a very promising vaccination strategy for Alzheimer's disease, which could prevent memory loss from occurring later in life," said professor Rakez Kayed, senior author of the study. "No safety concerns were detected in mice receiving this treatment, but more research is needed to confirm the efficacy and safety of immunisation in other animals and in humans," said Kayed. The study was published in the Journal of Neuroscience.