Pilot Projects Archive
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Pilot Projects funded in 2004-2005
Title: The Role of PKA during Basal Cell Carcinoma Development
Investigator(s): Xiaodong Cheng, Ph.D., Jingwu Xie, Ph.D.
Title: Development of Structure-Based Activators of Lens Aldehyde
Dehydrogenase 1
Investigator(s): Naseem Ansari, Ph.D., Robert Fox, Ph.D.
Title: Measurement of Bimarkers of Inflammation and Oxidative Stress in
Athletes Exposed to Moderate Levels of Particulate Pollution
Investigator(s): Edward Brooks, M.D., Sharon Petronella, Ph.D.
Title: Dynamics of RNA and DNA Recognition by HCV NS3 Helicase
Investigator(s): Wlodek Bujalowski, Ph.D.
Title: DNA Repair Pathways and 1,3-Butadiene (BD)-induced DNA Damage
Investigator(s): Jingwu Xie, Ph.D., Jeffrey Wickliffe, Ph.D.
Title: Functional Characterization of NEIL2 Polymorphisms
Investigator(s): Sherif Abdel-Rahman, Ph.D., Tapas Hazra, Ph.D.
Pilot Projects funded in 2003-2004
Title: Structural Studies of Oxidatively Damaged DNA Duplexes and the
Human NEIL2 DNA Binding Domain
Investigator(s): David G. Gorenstein, PhD
Title: A Directed Evolution Approach to Engineer Mammalian Cytochromes
P450 for Enhanced/Altered Biological Functions
Investigator(s): Santosh Kumar, PhD
Title: Community Forum Theater: A Flexible, Iterative Model for Dialogue
and Collaboration Among Citizens and NIEHS Center Investigators
Investigator(s): John Sullivan, MA
Title: Fate of hNSCs Grafted into Irradiated Rat Brain
Investigator(s): Yongia Yu, MD, MPH, PhD
Pilot Projects funded in 2002-2003
Title: Alteration of the Protein Ubiquitination in Lung Cancer
Investigator(s): Nonggao He, PhD and Jingwu Xie, PhD
Title: K-3 Theatre Outreach: Environmental Health Science Ed
Investigator(s): Cheryl L. Kaplan, MFA
Title: Using Theater as an Outreach Strategy for Scientific Education
Investigator(s): John Sullivan, MA
Pilot Projects funded in 2001-2002
Title: An Inducible Mouse Model for Basal Cell Carcinomas
Investigator(s): Jingwu Xie, PhD
Title: Effect of Persistent Virus Infection on Environmental
Insult-Induced Transcriptional Profiles
Investigator(s): Thomas B. Albrecht, PhD and Edward M. Postlethwait, PhD
Title: Epoxide Hydrolase and Butadiene-Induced Mutation in Mice
Investigator(s): Jonathan B. Ward, PhD and Marinel M. Ammenheuser, PhD
Title: Genetic Susceptibility to Cancer - Variations in DNA Repair
Investigator(s): William W. Au, PhD
Title: Role of Reactive Oxygen Species in Viral-Induced Transcription
Factor Activation
Investigator(s): Antonella Casola, MD
Pilot Projects funded in 2000-2001
Title: Allergen Induction in Mountain Cedar by Environmental Pollutants
Investigator(s): Terumi Midoro-Horiuti, MD, PhD; Edward G. Brooks, MD;
Randall M. Goldblum, MD; Edward M. Postlethwait, PhD
Title: Determining the Role of the Membrane Form of the Estrogen
Receptor-alpha in Mediating the Effects of Environmental Estrogens
Investigator(s): Cheryl S. Watson, PhD
Title: Engineering of a Soluble Form of Human Cytochrome P450
Investigator(s): Tammy L. Domanski, Ph.D. and James R. Halpert, PhD
Title: Impact of CYP2C9 Genotype on Long-term Warfarin Dose Requirement
Investigator(s): Hans von Marendorff, MD; Karl E. Anderson, PhD; Sherif
Abdel-Rahman, PhD; James J. Grady, PhD; Chul Lee, PhD
Title: Replication - Coupled Base Excision Repair
Investigator(s): Amanda K. McCullough, PhD
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