Rubing Chen, Ph.D.

Professional Education

Degree

Institution

Field of Study

Graduation Year

B.S.

Shaanxi Normal University, China

Biology

2002

M.Sc.

Shaanxi Normal University, China

Molecular Phylogenetics of Insects

2005

Ph.D.

Pennsylvania State University

Viral Evolution

2009

Post-Doctoral

University of Texas Medical Branch

Molecular Virology & Viral Evolution

Present

Honors           

2013  American Society for Virology Travel Award
2013  McLaughlin Travel Grant. UTMB
2013  The Robert L. Harrison Award. UTMB
2011-2013  Center for Tropical Diseases Postdoctoral Fellow. UTMB.
2009 Braddock Research Award. PSU
2008  Braddock Scholarship. PSU
2005-2007  Braddock Supplement. PSU
2005-2007  University Graduate Fellowship. PSU

Professional Societies and Affiliations

  • American Society of Virology

Research Interests

My research studies the viral transmission and pathogenesis from an evolutionary point of view.  Specifically, I am interested in integrating molecular evolution and experimental virology methods to identify the viral and host factors that influence the replication and transmission of arboviruses, as well as to translate this knowledge to understand and predict emergence into human populations.

Publications

  1. Chen R., Wang E., Tsetsarkin K.A., Weaver S.C. (2013) Chikungunya Virus 3’ Untranslated Region: Adaptation to Mosquitoes and a Population Bottleneck as Major Evolutionary Forces. PLoS Pathogens 9: e1003591.
  2. Diallo D., Chen R., Diagne C.T., Ba Y., Dia I., Sall A.A., Weaver S.C., Diallo M. (2013) Bloodfeeding patterns of sylvatic arbovirus vectors in southeastern Senegal. Trans R Soc Trop Med Hyg. 107:200-3.
  3. Weaver S.C., Osorio J.E., Livengood J.A., Chen R., Stinchcomb D.T. (2012) Chikungunya virus and prospects for a vaccine. Expert Rev Vaccines 11:1087-101.
  4. Diallo D., Sall A.A., Buenemann M., Chen R., Faye O., Diagne C.T., Faye O., Ba Y., Dia I., Watts D., Weaver S.C., Hanley K.A., Diallo M. (2012) Landscape ecology of sylvatic chikungunya virus and mosquito vectors in southeastern Senegal. PLoS Negl Trop Dis 6:e1649.
  5. Bahl J., Nelson M.I., Chan K.H., Chen R., et al. (2011) Temporally structured metapopulation dynamics and persistence of influenza A H3N2 virus in humans.Proc Natl Acad Sci U S A 108(48): 19359-64.
  6. Chen R., Vasilakis N. (2011) Dengue--quo tu et quo vadis? Viruses 3(9): 1562-608.
  7. Tsetsarkin K.A., Chen R., Sherman M.B., Weaver S.C. (2011) Chikungunya Virus: Evolution and Genetic Determinants of Emergence. Curr Opin Virol 1(4): 310-317.
  8. Tsetsarkin K.A., Chen R., Leal G., Forrester N., Higgs S., Huang J., Weaver S.C. (2011) Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes. Proc Natl Acad Sci U S A 108(19): 7872-7.
  9. Volk S.M.*, Chen R.*, Tsetsarkin K.A., et al. (2010) Genome Scale Phylogenetic Analyses of Chikungunya Virus Reveal Independent Emergences of Recent Epidemics and Varying Evolutionary Rates. Journal of Virology 84(13): 6495-6504 (*contributed equally)
  10. Chen R., Holmes E. C. (2010) Rapid Fixation of Internal Gene Segments in Avian Influenza Virus due to Genetic Hitchhiking. Journal of Molecular Evolution 70(1): 98-105.
  11. Chen R., Holmes E. C. (2009) Frequent inter-species transmission and geographic subdivision in avian influenza viruses from wild birds. Virology 383(1): 156-161.
  12. Dugan VG, Chen R, Spiro DJ, Sengamalay N, Zaborsky J, et al. (2008) The Evolutionary Genetics and Emergence of Avian Influenza Viruses in Wild Birds. PLoS Pathogens 4(5): e1000076.
  13. Chen R., Holmes E. C. (2008) The Evolutionary Dynamics of Human Influenza B Virus. Journal of Molecular Evolution. 66(6): 655-663.
  14. Chen R., Holmes E. C. (2006) Avian Influenza Virus Exhibits Rapid Evolutionary Dynamics. Molecular Biology & Evolution 23(12): 2336-2341.

Rubing Chen, Ph.D.

Rubing Chen, Ph.D.

Center for Tropical Diseases
Department of Pathology
University of Texas Medical Branch
4.138 Keiller Building
301 University Blvd.
Galveston, TX 77555-0609

Office Phone: (409) 747-2440
ruchen@utmb.edu