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Farooq Nasar

Farooq Nasar

Graduate Assistant, Pathology Education

University of Texas Medical Branch
301 University Boulevard
Galveston, TX 77555-1050

Office: (516) 298-8351
fanasar@utmb.edu

Professional Education

Degree Institution Field of Study Graduation Year
B.S. State University of New York at Albany Anthropology 1997
M.P.H. State University of New York at Albany Molecular Biology, and Environmental Health & Toxicology 2008

Honors

2000 David Axelrod Award for Excellence in Research, University at Albany.
2005 Wyeth Vaccines Research’s Above and Beyond Award, Wyeth Pharmaceuticals.

Research Interests

My research interests are characterizing novel Arboviruses utilizing both in vitro and in vivo models.  Additionally, I am pursuing new vaccine strategies for alphaviruses.

Selected Publications

  1. Jankowski C, Nasar F, Nag DK.  Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.  PNAS.  29;97(5):2134-9, 2000.
  2. Nasar F, Jankowski C, Nag DK.  Long palindromic sequences induce double-strand breaks during meiosis in yeast.  Mol Cell Biol.  20(10):3449-58, 2000.
  3. Cooper D, Pride MW, Guo M, Cutler M, Mester JC, Nasar F, She J, Souza V, York L, Mishkin E, Eldridge J, Natuk RJ.  Interleukin-12 redirects murine immune responses to soluble or aluminum phosphate adsorbed HSV-2 glycoprotein D towards Th1 and CD4+ CTL responses.  Vaccine.  25;23(2):236-46, 2004.
  4. Natuk RJ, Cooper D, Guo M, Calderon P, Wright KJ, Nasar F, Witko S, Pawlyk D, Lee M, DeStefano J, Tummolo D, Abramovitz AS, Gangolli S, Kalyan N, Clarke DK, Hendry RM, Eldridge JH, Udem SA, Kowalski J.  Recombinant vesicular stomatitis virus vectors expressing herpes simplex virus type 2 gD elicit robust CD4+ Th1 immune responses and are protective in mouse and guinea pig models of vaginal challenge.  J Virol.  80(9):4447-57, 2006.
  5. Cooper D, Mester JC, Guo M, Nasar F, Souza V, Dispoto S, Sidhu M, Hagen M, Eldridge JH, Natuk RJ, Pride MW.  Epitope mapping of full-length glycoprotein D from HSV-2 reveals a novel CD4+ CTL epitope located at the transmembrane-cytoplasmic junction.  Cell Immunol.  239(2):113-20, 2006.
  6. Johnson JE, Nasar F, Coleman JW, Price RE, Javadian A, Draper K, Lee M, Reilly PA, Clarke DK, Hendry RM, Udem SA.  Neurovirulence properties of recombinant vesicular stomatitis virus vectors in non-human primates.  Virology.  30;360(1):36-49, 2007.
  7. Clarke DK, Nasar F, Lee M, Johnson JE, Wright K, Calderon P, Guo M, Natuk R, Cooper D, Hendry RM, Udem SA.  Synergistic attenuation of vesicular stomatitis virus by combination of specific G gene truncations and N gene translocations.  J Virol.  81(4):2056-64, 2007.
  8. Coleman JW, Ogin-Wilson E, Johnson JE, Nasar F, Zamb TP, Clarke DK, Hendry RM, Udem SA.
    Quantitative multiplex assay for simultaneous detection of the Indiana serotype of vesicular stomatitis virus and HIV gag.  J Virol Methods.  143(1):55-64, 2007.
  9. Cooper D, Wright KJ, Calderon PC, Guo M, Nasar F, Johnson JE, Coleman JW, Lee M, Kotash C, Yurgelonis I, Natuk RJ, Hendry RM, Udem SA, Clarke DK.  Attenuation of recombinant vesicular stomatitis virus-human immunodeficiency virus type 1 vaccine vectors by gene translocations and g gene truncation reduces neurovirulence and enhances immunogenicity in mice.  J Virol.  82(1):207-19, 2008.
  10. Xu R, Nasar F, Megati S, Luckay A, Lee M, Udem SA, Eldridge JH, Egan MA, Emini E, Clarke DK.  Prime boost vaccination with recombinant mumps virus and recombinant vesicular stomatitis virus vectors elicits an enhanced human immunodeficiency virus type 1 Gag-specific cellular immune response in rhesus macaques.  J Virol.  83(19):9813-23, 2009.

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