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Dr. Wikel

Alexey Seregin

Graduate Assistant, Pathology Education

University of Texas Medical Branch
3.152 Keiller Building
301 University Boulevard
Galveston, TX 77555-0609

Office: (409) 747-2489
alseregi@utmb.edu

Professional Education


Degree Institution Field of Study Graduation Year
B.S., M.S. Novosibirsk State University, Novosibirsk, Russia Biology
(Cytology & Genetics)
1997–2002
Ph.D. Department of Pathology, University of Texas Medical Branch, Galveston, TX Graduate Student
( Experimental Pathology)
2006–Present

Honors


2010 Sealy Center for Vaccine Development Graduate Student Award

Professional Affiliations


2002–2007 Research Assistant, University of Kansas, Lawrence, KS
2007–2010 Visiting Scientist, University of Texas Medical Branch, Galveston, TX
2010–Present Graduate Student, University of Texas Medical Branch, Galveston, TX

Research Interests


My research interests are focused on the molecular mechanisms underlying the high pathogenicity of hemorrhagic arenaviruses.

Selected Publications


  1. Emonet Sx, Seregin AVx, Yun NE, Poussard AL, Walker AG, de la Torre JC, Paessler S. Rescue From Cloned cDNAs And In Vivo Characterization of Recombinant Pathogenic Romero And Life-Attenuated Candid #1 Strains Of Junin Virus, The Causative Agent Of Argentine Hemorrhagic Fever Disease. J Virol 2010; In Press (x – equal contribution).
  2. Seregin A.V., Yun N.E., Poussard A.L., Peng B.H., Smith J.K., Smith J.N., Salazar M., Paessler S., 2010. TC83 replicon vectored vaccine provides protection against Junin virus in guinea pigs. Vaccine 28(30), 4713-8.
  3. Paessler S., Rijnbrand R., Stein D.A., Ni H., Yun N.E., Dziuba N., Borisevich V., Seregin A., Ma Y., Blouch R., Iversen P.L., Zacks M.A., 2008. Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers. Virology 376(2), 357-70.
  4. Borisevich V, Nistler R, Hudman D, Yamshchikov G, Seregin A, Yamshchikov V.F., 2008. A highly sensitive and versatile virus titration assay in the 96-well microplate format. J Virol Methods 147(2), 197-205.
  5. Seregin, A., Nistler, R., Borisevich, V., Yamshchikov, G., Chaporgina, E., Kwok, C.W., Yamshchikov, V.F., 2006. Immunogenicity of West Nile virus infectious DNA and its noninfectious derivatives. Virology 356(1-2), 115-25.
  6. Borisevich, V., Seregin, A., Nistler, R., Mutabazi, D., Yamshchikov V.F., 2006. Biological properties of chimeric West Nile viruses. Virology 349(2), 371-81.
  7. Yamshchikov, G., Borisevich, V., Kwok, C.W., Nistler, R., Kohlmeier, J., Seregin, A., Chaporgina, E., Benedict, S., Yamshchikov, V.F., 2005. The suitability of yellow fever and Japanese encephalitis vaccines for immunization against West Nile virus. Vaccine 23(39), 4785-92.
  8. Yamshchikov, G., Borisevich, V., Seregin, A., Chaporgina, E., Mishina, M., Mishin, V., Kwok, C.W., Yamshchikov, V.F., 2004. An attenuated West Nile prototype virus is highly immunogenic and protects against the deadly NY99 strain: a candidate for live WN vaccine development. Virology 330(1), 304-12.

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