Mathilde Guerbois, Ph.D.
Post-Doctoral Fellow, Department of Pathology
University of Texas Medical Branch
4.139 Keiller Building
301 University Boulevard
Galveston, TX 77555-0609
Office: (409) 747-2440
Fax: (409) 747-2429
||Field of Study
||University of Lyon I (France)
||University of Paris VI
Major: Fundamental Virology
My current area of research is primarily focused on Arboviruses emergence. The idea is to determine how Arboviruses with important public health impacts emerge from a sylvatic cycle to circulate among human populations. I am participating in a study conducted in a rural area of Senegal, focusing on Dengue and Chikungunya viruses.
My second interest is in the development of vaccine strategies against Arboviruses and the study of there safety and stability.
- Guerbois M, Moris A, Combredet C, Najburg V, Ruffié C, Février M, Cayet N, Brandler S, Schwartz O, Tangy F.Live attenuated measles vaccine expressing HIV-1 Gag virus like particles covered with gp160ΔV1V2 is strongly immunogenic. Virology. 2009 May 25;388(1):191-203.
- Caignard G, Guerbois M, Labernardiere JL, Jacob Y, Jones LM; The Infectious Mapping Project I- MAP, Wild F, Tangy F, Vidalain PO. Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling. Virology. 2007 Nov 25;368(2):351-62.
- Frédéric Tangy, Samantha Brandler, Chantal Combredet Philippe Despres, Michèle Fevrier, Mathilde Guerbois, Valérie Labrousse-Najburg and Clarisse Lorin. Potential multivalent pediatric vaccines derived from a live attenuated measles virus expression vector. Review. Virus Expression Vectors, 2007: 299-317.
- Guillaume V, Aslan H, Ainouze M, Guerbois M, Wild TF, Buckland R, Langedijk JP. Evidence of a potential receptor-binding site on the Nipah virus G protein (NiV-G): identification of globular head residues with a role in fusion promotion and their localization on an NiV-G structural model. J Virol. 2006 Aug;80(15):7546-54.