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Mathilde Guerbois, Ph.D.

Mathilde Guerbois, Ph.D.

Post-Doctoral Fellow, Department of Pathology

University of Texas Medical Branch
4.139 Keiller Building
301 University Boulevard
Galveston, TX 77555-0609

Office: (409) 747-2440
Fax: (409) 747-2429
maguerbo@utmb.edu

Professional Education


Degree Institution Field of Study Graduation Year
B.A. University of Lyon I (France) Fundamental Virology 2004
Ph.D. University of Paris VI Microbiology
Major: Fundamental Virology
2008

Research Interests


My current area of research is primarily focused on Arboviruses emergence. The idea is to determine how Arboviruses with important public health impacts emerge from a sylvatic cycle to circulate among human populations. I am participating in a study conducted in a rural area of Senegal, focusing on Dengue and Chikungunya viruses.

My second interest is in the development of vaccine strategies against Arboviruses and the study of there safety and stability.

Selected Publications


  1. Guerbois M, Moris A, Combredet C, Najburg V, Ruffié C, Février M, Cayet N, Brandler S, Schwartz O, Tangy F.Live attenuated measles vaccine expressing HIV-1 Gag virus like particles covered with gp160ΔV1V2 is strongly immunogenic. Virology. 2009 May 25;388(1):191-203.
  2. Caignard G, Guerbois M, Labernardiere JL, Jacob Y, Jones LM; The Infectious Mapping Project I- MAP, Wild F, Tangy F, Vidalain PO. Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling. Virology. 2007 Nov 25;368(2):351-62.
  3. Frédéric Tangy, Samantha Brandler, Chantal Combredet Philippe Despres, Michèle Fevrier, Mathilde Guerbois, Valérie Labrousse-Najburg and Clarisse Lorin. Potential multivalent pediatric vaccines derived from a live attenuated measles virus expression vector. Review. Virus Expression Vectors, 2007: 299-317.
  4. Guillaume V, Aslan H, Ainouze M, Guerbois M, Wild TF, Buckland R, Langedijk JP. Evidence of a potential receptor-binding site on the Nipah virus G protein (NiV-G): identification of globular head residues with a role in fusion promotion and their localization on an NiV-G structural model. J Virol. 2006 Aug;80(15):7546-54.

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