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Olga Lihoradova

Olga Lihoradova, Ph.D.

Post-Doctoral Fellow, Department of Pathology

University of Texas Medical Branch
2.208 Administration Building
301 University Boulevard
Galveston, TX 77555-0140

Office: (409) 772-2560
ollihora@utmb.edu

Professional Education

Degree Institution Field of Study Graduation Year
B.S. National University of Uzbekistan, Tashkent Molecular Biology
and Biotechnology		 1999
M.Sc. National University of Uzbekistan, Tashkent Molecular Biology
and Biotechnology		 2001
Ph.D. Uzbek Academy of Sciences Bioorganic Chemistry and Biotechnology 2008
Post-Doctoral University of Texas Medical Branch, Galveston, TX Molecular Virology Current

Honors

Patents and Copyrights Awarded

Lihoradova, O.A, Azimova, Sh.S. (2002) Recombinant plasmid DNA pBHep-2, encoding preS2-S region of human hepatitis B virus (M-HBsAg) and method of its construction. Patent of Republic Uzbekistan IAP 03178.

Perepada, K.A., Lihoradova, O.A., Azimova, Sh.S. (2003) Recombinant plasmid DNA, encoding human erythropoietin and method of its construction. Patent of Republic Uzbekistan IAP 03545.

Professional Affiliations

American Society for Virology

Research Interests

My area of research is primarily focused on molecular virology studies in the field of vaccines development by using recombinant proteins.

Selected Publications

Articles published in refereed journals

  1. Lihoradova, O.A., Ogay, I.D., Podpisnova, M.M., Slack, J.M., Azimova, Sh.S. (2008) Expression of a Foreign Gene by Cysteine Proteinase Null Recombinant Baculovirus. Molecular Biology (Moscow). 42(2):328–334.
  2. Lihoradova, O.A., Ogay, I.D., Abdukarimov, A.A., Azimova, Sh.S., Lynn, D.E., Slack, J.M. (2007) The Homingbac baculovirus cloning system: An alternative way to introduce foreign DNA into baculovirus genomes. J Virol Methods. 140:59-65.
  3. Ogay, I.D., Lihoradova, O.A., Azimova, Sh.S., Slack, J.M., Lynn, D.E. (2006) Transfection of insect cell lines using polyethylenimine. Cytotechnology. 51(2):89-98
  4. Bachurina, E.Yu., Lihoradova, O.A., Zholdasova, Е.А., Piyakina, G.A., Azimova, Sh.S. (2005) Isolation and purification of recombinant human hepatitis B HBsAg from silkworm larvae. Chemistry of Natural Compounds. 41(5):583-587
  5. Lihoradova, O.A., Bachurina, E.Yu., Azimova, Sh.S. (2004) Biosynthesis of recombinant human hepatitis B virus M-HBsAg in silkworm larvae. Molecular Biology (Moscow). 38(4):603–607.

Papers in refereed conference proceedings, posters, etc.

  1. Sadikova, G.B., Lihoradova, O.A.*, Azimova, Sh.S. (2009) Cloning of whole-size human erythropoietin gene. International conference “Actual problems of the chemistry of natural compounds” Tashkent 18-19 March 2009, p 105 (International conference)
  2. Lihoradova, O.A.*, Ogay, I.D., Podpisnova, M.M., Azimova, Sh.S. (2008) Obtaining of recombinant human Müllerian Inhibiting Substance (MIS) by using baculovirus expression system. 41th Annual Meeting of the Society for Invertebrate Pathology, Coventry, United Kingdom, p.103 (International conference)
  3. Slack, J.M.*, Lihoradova, O.A., Ogay, I.D., Azimova, Sh.S., Dedes, J., Schwarz, R., Krell, P.J., Arif, B.M. (2008) Applying an Anticarsia gemmatalis Multiple Nucleopolyhedrovirus (AgMNPV)-based direct cloning system to make a cDNA expression library of the cottonwood borer beetle (Plectrodera scalator) 41th Annual Meeting of the Society for Invertebrate Pathology, Coventry, United Kingdom, p.102 (International conference).
  4. Lihoradova, O.A.*, Ogay, I.D., Slack, J.M, Azimova, Sh.S. (2007) Expression of foreign protein by a polyhedrin-positive, cathepsin null recombinant baculovirus. 40th Annual Meeting of the Society for Invertebrate Pathology, Quebec City, Canada, p.52. (International conference)
  5. Slack, J.M.*, Lihoradova, O.A., Ogay, I.D., Schwarz, R., Azimova, Sh.S., Krell, P.J. and Arif, B.M. (2007) Development of a direct cloning system for the baculovirus, Anticarsia gemmatalis Multiple Nucleopolyhedrovirus (AgMNPV). 40th Annual Meeting of the Society for Invertebrate Pathology, Quebec City, Canada, p.91. (International conference)
  6. Ogay, I.D.*, Lihoradova, О.А., Azimova, Sh.S., Abdukarimov, A.A. (2006) Constructing of recombinant baculoviruses Autographa californica MNPV, Plutella xylostella MNPV, Rachoplusia ou MNPV, Helicoverpa armigera MNPV and Bombyx mori NPV by using common transfer vector. Conf. Of Young Scientists, Tashkent. (Regional conference)
  7. Lihoradova, O.A.*, Ogay, I.D., Slack, J.M , Abdukarimov, A.A. (2006) A novel direct cloning system for making recombinant baculoviruses. 39th Annual Meeting of the Society for Invertebrate Pathology, Wuhan, P.R. China, p.78. (International conference)
  8. Lihoradova, O.A.*, Slack, J.M. (2005) Baculovirus transfer vector for V-CATH deletion. Conf. Of Young Scientists, Tashkent. (Regional conference)
  9. Lihoradova, O.A*, Zholdasova, E.A., Bachurina, E.Yu, Azimova, Sh.S. (2004) Expression of recombinant human hepatitis B virus surface antigens by baculovirus expression system. The 8th International Pushchino School-conference of Young Scientists "Biology the Science of the XXI Century", Pushchino (Russia). (International conference)
  10. Lihoradova, O.A*, Zholdasova, E.A., Piyakina, G.A., Azimova, Sh.S. (2004) Purification of nuclear polyhedrosis virus from Helicoverpa armigera larvae. Conf. Of Young Scientists, Tashkent. (Regional conference)
  11. Azimova, Sh.S., Piyakina, G.A., Yusupova, E.G., Lihoradova, O.A*, Bachurina, E.Yu, Zaitov, I.R., Ogay, I.D., Polarush, S.V., Zholdasova, E.A. (2003) Using recombinant proteins obtained on the basis of baculovirus technology. International workshop on biotechnology commercialization and security. Tashkent, p. 10.
  12. Lihoradova, O.A*, Polarush, S.V., Zholdasova, E.A., Azimova, Sh.S. (2002) Expression of recombinant proteins in Bombyx mori larvae and studying of heterology gene inheritance in silkworm. Conf. Applied Biotechnology, Tashkent, p. 21. (International conference)
  13. Lihoradova, O.A*, Zaitov, I.R., Dolgushina, N.E., Perepada, K.A., Azimova, Sh.S. (2002) Modification of baculovirus vector pBE 284., Conf. Of Young Scientists, Tashkent, p. 99. (Regional conference)
  14. Lihoradova, O.A*, Perepada K.A., Zaitov I.R., Ogay I.D., Zholdasova Е.A., Azimova Sh.S. Expression of recombinant HBsAg in E.coli. Materials of the Inter. Conf. “Problems and future prospects of biology, ecology and agrology”. Tashkent, 2000, p. 157. (Regional conference).

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