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Dr. Xu

Ya Xu, MD

Resident, Department of Pathology

University of Texas Medical Branch
301 University Boulevard
Galveston, TX 77555-0743

Office: (409) 772-2870
yaxu@utmb.edu

Professional Education


Degree Institution Field of Study Graduation Year
M.D. West China University of Medical Sciences, Chengdu, Sichuan, China   1990
Ph.D. Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China   1997
Visiting Scientist Department of Neurosciences and Cell Biology, University of Texas Medical Branch, Galveston, TX   2004
Research Associate Department of Pathology, University of Texas Medical Branch, Galveston, TX   2010

Honors


2011 The Edward S. Reynolds Award for Pathology Research, UTMB, Galveston, Texas
2010 The Robert L. Harrison Award for Pathology Research, UTMB, Galveston, Texas
2009 The Robert L. Harrison Award for Pathology Research, UTMB, Galveston, Texas
2006 1st Place Postdoctoral Fellow Award for Molecular/Cellular Biology Research, UTMB, Galveston, Texas
2005 2nd Place Postdoctoral Fellow Award for Mechanistic/Basic Research, UTMB, Galveston, Texas

Professional Affiliations


2011 College of American Pathologist
2010-Present United States & Canadian Academy of Pathology
2010-Present American Society for Clinical Pathology
2010-Present Texas Society for Pathologists
1999-2003 The Society for Neuroscience
1992-1998 Chinese Society of Pathology, Chinese Medical Association

Research Interests


Cardiovascular disease and Tumor pathogenesis

Selected Publications


  1. Xu, Y., Gong, B., Yang, Y., Awasthi, YC., Boor, PJ. Adenovirus-mediated overexpression of Glutathione-S-Transferase mitigates transplant arteriosclerosis in rabbit carotid allografts. Transplantation, 89(4):409-416, 2010
  2. Yang, Y., Yang, Y., Xu, Y., Lick, SD., Awasthi, YC., Boor, PJ. Endothelial glutathione-S-transferase A4-4 protects against oxidative stress and modulates iNOS expression through NF-kappaB translocation. Toxicology and Applied Pharmacology, 230(2): 187-196, 2008
  3. Gong, B., Sun, J., Vargas, G., Chang, Q., Xu, Y., Srivastava, D., Boor, PJ. Nonlinear imaging study of extracellular matrix in chemical-induced, developmental dissection aortic aneurysm: Evidence for defective collagen type III. Birth Defects Research Part A: Clinical Molecular Teratology, 82(1): 16-24, 2008
  4. Xu, Y., Gong, B., Yang, Y., Awasthi, YC., Woods, M., Boor, PJ. Glutathione-S-Transferase protects against oxidative injury of endothelial cell tight junctions. Endothelium, 14(06): 333–343, 2007
  5. Wang, L., Yang, Y., Dwivedi, S., Xu, Y., Chu, E., Li, J., Fitchett, K., and Boor, P. Manipulation Glutathione-S-Transferases may prevent the development of tolerance to nitroglycerin. Cardiovascular Toxicology, 6: 131-144, 2006
  6. Gu, Y., Xu, Y., Li, GW., and Huang, L.-Y. Remote nerve injection of mu opioid receptor adeno-associated viral vector increases antinociception of intrathecal morphine. Journal of Pain, 6: 447-454, 2005
  7. Xu, Y., Wu, P. and Huang, L.-Y. M. Efficiencies of transgene expression in nociceptive neurons through different routes of delivery of adeno-associated viral vectors. Human Gene Therapy, 14: 897-906, 2003
  8. Xu, Y., Gu, Y., Xu, G-Y., Wu, P. et al. Adeno-associated viral transfer of opioid receptor gene to primary sensory neurons: a strategy to increase opioid antinociception. Proceedings of National Academy of  Sciences in U S A, 100: 6204-9, 2003
  9. Xu, Y. “Techniques in tumor diagnostic pathology” in “Pediatric Tumor Pathology”(ed Li, Peijuan.), 16-32.  Beijing Publishing House, Beijing, 2001
  10. Xu Y, Chen J, Liu T, Gu L, Gao J, Li L. Changes of p16 gene, cyclin D1 gene, and pRb protein in human pancreatic adenocarcinoma cell lines. Acta Academiae Medicinae Sinicae. Dec;22(6):566-9, 2000
  11. Xu, Y., Liu, T. and Gao, J. Effects of blocking the TGFα-EGFR autocrine loop on the growth of pancreatic carcinoma cells in vitro. Acta Academiae Medicinae Sinicae, 21:1-7, 1999
  12. Xu, Y., and Liu, H. Pulmonary histiocytosis-a case report. Chinese Journal of Pathology, 28:233-235, 1998
  13. Xu, Y., Liu, T. and Gao, J. Effects of antisense cyclin D1 expressing vector on the cell growth and apoptosis in human pancreatic carcinoma cell line. Chinese Journal of Pathology, 27:348-351, 1998
  14. Xu, Y., Liu, T. and Gao, J. Influence of recombinant retroviral vector expressing antisense TGFα on malignant phenotype of human pancreatic carcinoma cell line (in English). Chinese Medical Journal, 111:334-338, 1998
  15. Xu, Y. and Cui, Q. Ependymoma with melanin and lipofuscin. Journal of Diagnostic Pathology, 2:56-58, 1995
  16. Xu, Y. and Liu, H. Malignant small cell mesothelioma. Chinese Journal of Oncology, 16:221-223, 1994
  17. Fang, X. and Xu, Y. Clinical and Pathological Consultation: Abdominal pain, abdominal mass and ascites. Chinese Journal of Pathology, 22:248-252, 1993
  18. Xu, Y. and Liu, H. Papillary adenoma of the lung – two cases report. Chinese Journal of Tuberculosis and Respiratory Diseases, 15:296-299, 1992
  19. Xu, Y. and Yang, J. Systemic lupus erythematosus – an autopsy case report. Beijing Medical Journal, 13:5-8, 1991

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