Perenlei Enkhbaatar, M.D., Ph.D.

Perenlei Enkhbaatar, M.D., Ph.D.

Associate professor, Department of Anesthesiology

University of Texas Medical Branch
301 University Blvd,
Galveston, TX 77555-1102

Office: (409) 747-0096
Fax: (409) 772-6409
peenkhba@utmb.edu

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Perenlei Enkhbaatar, M.D., Ph.D.

Professional Education

Degree Institution Field of Study Graduation Year
M.D.

Medical Doctor, Military Medical Academy, Saint Petersburg, Russia

Medicine 1986
Ph.D. Medical School, Kumamoto University, Kumamoto, Japan   2001
Post-Doctoral Department of Anesthesiology, University of Texas Medical Branch, TX Anesthesiology 2003

Honors

Honored Graduate Diploma from Military Medical Academy, Saint-Petersburg, Russia

Professional Affiliations

  • Society of Critical Care Medicine
  • American Burn Association
  • Shock Society
  • American Thoracic Society
  • American Physiological Society
  • American Heart Association
  • Society of Surgical Infection

Journal Reviewer:

  • Critical Care Medicine
  • Journal of Applied Physiology
  • Clinical and Experimental Pharmacology and Physiology
  • Burns

Journal Editorial Board Member:

  1. Clinical Medicine: Case Reports
  2. International Journal of General Medicine

Research Interests

Pathophysiology of cardiopulmonary morbidity due to multiple traumas such as sepsis, smoke inhalation and cutaneous burn. Main focus is role of excessive nitric oxide, neutrophil dysfunction and coagulapthy in these pathological conditions. Main purpose is to describe the pathophysiological mechanisms of multiple trauma-related cardiopulmonary dysfunctions and find effective treatment approaches. Currently, I am investigating the differential host responses to different bacterial infections namely, Gram-positive and –negative bacteria. The results of our current research will propose new treatment strategy against sepsis-induced multiple organ failure targeting both nature of different infectious sources and specific host responses to them.

Selected Publications

  1. Maybauer DM, Maybauer MO, Szabó C, Westphal M, Traber LD, Enkhbaatar P, Murthy KG, Nakano Y, Salzman AL, Herndon DN, Traber DL. Lung-protective effects of the metalloporphyrinic peroxynitrite decomposition catalyst WW-85 in interleukin-2 induced toxicity. Biochem Biophys Res Commun. 377:786-7891, 2008
  2. Enkhbaatar P, Lange M, Nakano Y, Hamahata A, Joncam C, Wang J, Jaroch S, Traber L, Herndon D, Traber D. Role of Neuronal Nitric Oxide Synthase in Ovine Sepsis Model. Shock 32:253-257, 2009
  3. Enkhbaatar P, Connelly R, Wang J, Nakano Y, Lange M, Hamahata A, Horvath E, Szabo C, Jaroch S, Hölscher P, Hillmann M, Traber LD, Schmalstieg FC, Herndon DN, Traber DL. Inhibition of neuronal nitric oxide synthase in ovine model of acute lung injury. Crit Care Med. 37:208-214, 2009
  4. Lange M, Connelly R, Traber DL, Hamahata A, Cox RA, Nakano Y, Bansal K, Esechie A, von Borzyskowski S, Jonkam C, Traber LD, Hawkins HK, Herndon DN, Enkhbaatar P. Combined neuronal and inducible nitric oxide synthase inhibition in ovine acute lung injury. Crit Care Med. 37:223-229, 2009
  5. Enkhbaatar P, Herndon DN, Traber DL. Use of nebulized heparin in the treatment of smoke inhalation injury. J Burn Care Res. 30:159-162, 2009
  6. Palmieri TL, Enkhbaatar P, Sheridan R, Traber DL, Greenhalgh DG. Studies of inhaled agents in inhalation injury. J Burn Care Res. 30:169-171, 2009
  7. Traber DL, Traber MG, Enkhbaatar P, Herndon DN. Tocopherol as treatment for lung injury associated with burn and smoke inhalation. J Burn Care Res. 30:164-165, 2009
  8. Jonkam CC, Bansal K, Traber DL, Hamahata A, Maybauer MO, Maybauer DM, Cox RA, Lange M, Connelly RL, Traber LD, Djukom CD, Salsbury JR, Herndon DN, Enkhbaatar P. Pulmonary vascular permeability changes in an ovine model of methicillin-resistant Staphylococcus aureus sepsis. Crit Care. 13:R19, 2009
  9. Cox RA, Jacob S, Oliveras G, Murakami K, Enkhbaatar P, Traber L, Schmalstieg FC, Herndon DN, Traber DL, Hawkins HK. Pulmonary expression of nitric oxide synthase isoforms in sheep with smoke inhalation and burn injury. Exp Lung Res. 35:104-118, 2009
  10. Lange M, Enkhbaatar P, Nakano Y, Traber DL. Role of nitric oxide in shock: the large animal perspective. Front Biosci. 14:1979-1989, 2009.
  11. Jonkam CC, Lange M, Traber DL, Maybauer DM, Maybauer MO, Bansal K, Hamahata A, Zhu Y, Esechie A, Traber LD, Sousse L, Rehberg S, Herndon DN, Enkhbaatar P. Cardiovascular Collapse and Vascular Permeability Changes in an Ovine Model of Methicillin-Resistant Staphylococcus aureus Sepsis. Shock 32:621-625,
  12. Hamahata A, Enkhbaatar P, Hiroyuki S, Nozaki M, Traber DL. Effect of ablated bronchial blood flow on survival rate and pulmonary function after burn and smoke inhalation in sheep. Burns 35: 802-810, 2009
  13. Cox RA, Burke AS, Jacob S, Oliveras G, Murakami K, Shimoda K, Enkhbaatar P, Traber LD, Herndon DN, Traber DL, Hawkins HK. Activated Nuclear Factor Kappa B and Airway Inflammation After Smoke Inhalation and Burn Injury in Sheep. J Burn Care Res. 30:489-498, 2009
  14. Lange M, Enkhbaatar P, Traber DL, Cox RA, Jacob S, Mathew BP, Hamahata A, Traber LD, Herndon DN, Hawkins HK. Role of Calcitonin Gene-Related Peptide (CGRP) in Ovine Burn and Smoke Inhalation Injury. J Appl Physiol 107:176-184, 2009
  15. Rehberg S, Maybauer MO, Enkhbaatar P, Maybauer DM, Yamamoto Y, Traber DL. Pathophysiology, management and treatment of smoke inhalation injury. Expert reviews in Respiratory Medicine (in press)
  16. Rehberg S, Maybauer MO, Maybauer DM, Enkhbaatar P, Traber MG, Traber DL. The antioxidants vitamin E and vitamin C for nutritional support in critical ill patients: beneficial or harmful? Adv Anaesthesiol Crit Care 1:11-19, 2009
  17. Rehberg S, Maybauer MO, Maybauer DM, Traber LD, Enkhbaatar P, Traber DL. The role of nitric oxide and reactive nitrogen species in experimental acute respiratory distress syndrome. Frontiers in Bioscience (in press)
  18. Rehberg S, Enkhbaatar P, Traber DL. Arginine vasopressin in septic shock: supplement or substitute for norepinephrine? Crit Care 13:178, 2009
  19. Esechie A, Enkhbaatar P, Traber DL, Jonkam C, Lange M, Hamahata A, Djukom C, Whorton EB, Hawkins HK, Traber LD, Szabo C. Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn- and smoke-induced acute lung injury. Br J Pharmacol 2009 158:1442-1453, 2009
  20. Saunders FD, Westphal M, Enkhbaatar P, Wang J, Pazdrak K, Nakano Y, Hamahata A, Jonkam CC, Lange M, Connelly R, Kulp GA, Cox RA, Hawkins HK, Schmalstieg FC, Horvath E, Szabo C, Traber LD, Whorton E, Herndon DN, Traber DL. Molecular Biological Effects of Selective Neuronal Nitric Oxide Synthase Inhibition in Ovine Lung Injury. Am J Physiol Lung Cell Mol Physiol 2009 [E-Pub]

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