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A. Paige Adams, D.V.M., Ph.D.

Assistant Professor, Department of Pathology;
Member, WHO Collaborating Center for Tropical Diseases;
Member, Center for Biodefense & Emerging Infectious Diseases;
Member, Sealy Center for Vaccine Development

Department of Pathology
University of Texas Medical Branch
Keiller Building, Room 3.108
301 University Blvd.
Galveston, TX 77555-0609

Office: (409) 747-0650
Lab: (409) 747-2425
Fax: (409) 747-2429 apadams@utmb.edu

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A. Paige Adams, D.V.M., Ph.D.

Professional Education

Degree Institution Field of Study Graduation Year
Ph.D. Cornell University Immunology 2004
D.V.M. Texas A&M University Veterinary Medicine 1993
B.S. Texas A&M University Veterinary Science 1990

Honors

1986-1990 Houston Livestock Show & Rodeo Scholarship, Texas A&M University
1987 Phi Eta Sigma Honor Society (top 5%), Texas A&M University
1988 Bruce McGee College of Agriculture Scholarship, Texas A&M University
1989 Alpha Zeta Agricultural Honor Society, Texas A&M University
1989 Charles J. Koerth Sr. Memorial Scholarship, Texas A&M University
1990 Cum Laude, Bachelor of Science, Veterinary Science, Texas A&M University
1993 Phi Zeta Veterinary Honor Society, Texas A&M University
1993 Cum Laude, Doctor of Veterinary Medicine, Texas A&M University
1999 Resident Research Publication Award (2nd place), American College of Veterinary Surgeons (ACVS)
2003 Graduate Student Award (1st place), American Association of Veterinary Immunologists (AAVI)
2006-2008 James W. McLaughlin Postdoctoral Fellowship, University of Texas Medical Branch
2007 Postdoctoral Fellow Travel Award, American Society for Virology (ASV)
2007 Postdoctoral Fellow Travel Award, American Society of Tropical Medicine and Hygiene (ASTMH)
2010 Advanced Scholar, Translational Research Scholar Program, Institute for Translational Sciences, University of Texas Medical Branch

Professional Affiliations

1993-Present Member, American Veterinary Medical Association
1993-Present Member, Texas Veterinary Medical Association
1997-Present Member, American Association of Equine Practitioners
1998-Present Member, American Association of Immunologists
1999-Present Member, American Association of Veterinary Immunologists
2006-Present Member, American Society for Virologists
2007-Present Member, American Society of Tropical Medicine and Hygiene
2009-Present Member, Sealy Center for Vaccine Development (SCVD), University of Texas Medical Branch
2010-Present Member, Center for Biodefense and Emerging Infectious Diseases (CBEID) and PAHO/WHO Collaborating Center for Tropical Diseases, University of Texas Medical Branch
2010-Present Member, American Society for Microbiology

Research Interests

  • Immunopathology and infectious disease pathogenesis of alphaviruses in rodent, equine, and non-human primate animal models.
  • Innate and adaptive immune responses to alphaviruses.
  • Vaccine development for biodefense pathogens.
  • Phylogenetics and evolutionary processes of viruses as they relate to emergence and/or re-emergence

Selected Publications

  1. Auguste AJ, Adams AP, Arrigo NC, Martinez R, Travassos Da Rosa APA, Adesiyun AA, Chadee DD, Tesh RB, Carrington CVF, Weaver SC. Isolation and characterization of sylvatic mosquito-borne viruses in Trinidad: Enzootic transmission and a new potential vector of Mucambo virus. AJTMH 2010;83:1262-1265.
  2. Arrigo NC, Adams AP, Watts DM, Newman PC, Weaver SC. Cotton rats (Sigmodon hispidus) and house sparrows (Passer domesticus) as amplification hosts of North and South American strains of eastern equine encephalitis virus. EID 2010;16:1373-1380.
  3. Volk SM, Chen R, Tsetsarkin KA, Adams AP, Garcia TI, Sall AA, Nasar F, Schuh AJ, Holmes EC, Higgs S, Brault AC, Maharaj PD, Weaver SC. Genome scale phylogenetic analyses of chikungunya virus reveal independent emergences of recent epidemics and varying evolutionary rates. J Virol 2010;84:6497-6504.
  4. Kenney JL, Adams AP, Weaver SC. Transmission potential of two chimeric western equine encephalitis vaccine candidates in Culex tarsalis. Am J Trop Med Hyg 2010;82:354-359.
  5. Arrigo NC, Adams AP, Weaver SC. Evolutionary patterns of eastern equine encephalitis virus in North versus South America suggest ecological differences and taxonomic revision. J Virol 2010;84:1014-1025.
  6. Aguilar PV, Adams AP, Vargas J, Mannock S, Diaz A, Liang X, Roca Y, Weaver SC, Kochel TJ. Endemic circulation of Venezuelan equine encephalitis virus in Bolivia, Ecuador and Peru: Identification of a new subtype ID genetic lineage. PLoS Negl Trop Dis 2009;3:e514.
  7. Auguste AJ, Volk SM, Arrigo NC, Martinez R, Ramkissoon V, Adams AP, Thompson NN, Adesiyun AA, Chadee DD, Foster JE, Travassos Da Rosa AP, Tesh RB, Weaver SC, Carrington CVF. Isolation and phylogenetic analysis of Mucambo virus (Venezuelan equine encephalitis virus subtype IIIA) in Trinidad. Virology 2009;392:123-130.
  8. Atasheva S, Wang E, Adams AP, Plante KS, Ni S, Taylor K, Miller ME, Frolov I, Weaver SC. Chimeric alphavirus vaccine candidates provide complete protection in mice after intranasal challenge with western equine encephalitis virus. Vaccine 2009;27:4309-4319.
  9. Adams AP, Aronson JF, Tardif SD, Patterson JL, Brasky KM, Geiger R, de la Garza M, Carrion R, Jr., Weaver SC. Common marmosets (Callithrix jacchus) as a nonhuman primate model to assess the virulence of eastern equine encephalitis virus strains. J Virol 2008;82:9035-9042.
  10. Wang E, Volkova E, Adams AP, Forrester N, Xiao S-Y, Frolov I, Weaver SC. Chimeric alphavirus vaccine candidates for chikungunya. Vaccine 2008;26:5030-5039.
  11. Aguilar PV, Adams AP, Wang E, Carrara A-S, Anishchenko M, Frolov I, Weaver SC. Structural and nonstructural genes of eastern equine encephalitis virus are determinants of interferon sensitivity and mouse neurovirulence. J Virol 2008;82:4920-4930.
  12. Smith DR, Adams AP, Kenney JL, Wang E, Weaver SC. Venezuelan equine encephalitis virus in the mosquito vector Aedes taeniorhynchus: infection initiated by a small number of susceptible epithelial cells and a population bottleneck. Virology 2008;372:176-186.
  13. Wang E, Petrakova O, Adams AP, Aguilar PV, Kang W, Paessler S, Frolov I, Weaver SC. Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice. Vaccine 2007;25:7573-7581.
  14. Adams AP, Oriol RE, Campbell RE, Oppenheim YC, Antczak DF. The effect of skin allografting on the equine endometrial cup reaction. Theriogenology 2007;68:237-247.
  15. Adams AP, Antczak DF. Ectopic transplantation of equine invasive trophoblast. Biol Reprod 2001;64:753-763.
  16. Adams AP, Santschi EM, Mellencamp MA. Antibacterial properties of a silver chloride-coated nylon wound dressing. Vet Surg 1999;28:219-225.
  17. Boussauw B, Santschi EM, Wilderjans H, Troedsson MH, Adams AP. Uterine drainage under general anaesthesia before ovariohysterectomy in two mares. Vet Rec 1998;142:582-583.
  18. Adams AP, Collatos C, Fuentealba C, Illanes O, Blanchard R. Neuroaxonal dystrophy in a two year old Quarter Horse filly. Can Vet J 1996;37:43-44.
  19. Adams AP, Honnas CM, Ford TS, Watkins JP. Arthrodesis of a subluxated proximal interphalangeal joint in a horse. Equine Pract1995;17(3):26-31.

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