David Walker

Update Your Profile
Profile URL: www.utmb.edu/pathology/profiles/?user=dwalker
David Walker
Contact Information
Email:

Directory lookup

Academic Appointments
Appointment Organization
Professor Pathology
Chairman Pathology
Professional Education
Degree Institution Field of Study Graduation Year
Clinical Fellow Harvard University, School of Medicine Pathology 1973
Senior Assistant Resident Peter Bent Brigham Hospital Clinical Pathology 1973
Research Fellow Harvard University, School of Medicine Pathology 1972
Research Gorgas Memorial Laboratory Tropical Pathology 1971
Chief Resident Peter Bent Brigham Hospital Pathology 1971
Junior Assistant Resident Peter Bent Brigham Hospital Pathology 1971
Intern Peter Bent Brigham Hospital Pathology 1970
M.D. Vanderbilt University, School of Medicine Professional Curriculum 1969
B.A. Davidson College History 1965
Honors
Title Organization Year(s)
Mustard Seed Award in Research, Sealy Society, University of Texas Medical Branch 1997
Docteur Honoris Causa, Universite de la Mediterranee. Marseille, France 1996
Designated Technical Advisor, Epidemiology and Etiology of Spotted Fever, Rickettsiosis in Inner Mongolia Project, Inner Mongolia Anti-epidemic Station. The People's Republic of China 1991 - 1995
Designated Visiting Professor, Department of Microbiology. Sun Yat-sen University of Medical Sciences. Guangzhou, The People's Republic of China 1990 - 1992
Infectious Diseases Society of America, Fellow 1981
Justin Potter Merit Scholarship, Vanderbilt University, School of Medicine. Nashville, Tennessee 1965 - 1969
Phi Beta Kappa 1963
Professional Affiliations
Society Year(s)
American Society of Tropical Medicine and Hygiene. Nominating Committee, Chair 1998 1996 - 1998
Texas Society of Pathology Member, Liaison Committee to Texas Department of Health 1996
Texas Branch, American Society for Microbiology 1991
Chauncey Leake History of Medicine Society 1991
Texas Society of Pathologists, Inc.* 1989
American Society of Clinical Pathologists, Inc.* 1989
Galveston County Medical Society* 1988
College of American Pathologists Fellow* 1988
Houston Society of Clinical Pathologists 1988
Binford-Dammin Society of Infectious Disease Pathologists. President, 1989-90; Secretary-Treasurer, 1995-2001 1988
Association of Pathology Chairmen, Inc. 1988
Texas Medical Association (H5380)* 1988
American Association for the Advancement of Science 1988
Sigma Xi, The Scientific Research Society 1987
Infectious Diseases Society of America . Fellow* 1981
American Society of Rickettsiology. Vice President, 1988-89; President, 1989-91 1979
Society for Pediatric Pathology 1978 - 1996
United States-Canadian Division of the International Academy of Pathology. Council Member 1996-2000 1975
American Society for Investigative Pathology -
American Society for Microbiology -
Research Interests

Intracellular Bacterial Diseases

My research interests are broadly in the area of obligately intracellular bacteria that are transmitted by arthropod vectors. Two research projects currently funded by the NIH are focused on immune mechanisms against rickettsiae and ehrlichiae and identification of the immuno-dominant surface protein antigens that stimulate immunity. Although the diseases caused by rickettsiae include many long known and feared life-threatening infections such as Rocky Mountain spotted fever and epidemic typhus, elucidation of their molecular composition and effector immune mechanisms remain productive lines of investigation. In contrast, human ehrlichioses are truly emerging infectious diseases that were unknown until recently and are causing increasingly prevalent, severe infections. Nearly everything regarding ehrlichial life cycle, pathogenesis and immunity is in the process of being discovered and investigated at present for these novel organisms. My research on immunity pursues hypotheses involving studies of dendritic cells, cytokines, chemokines, cytotoxic T-lymphocytes, nitric oxide, antibodies, endothelial biology and intracellular killing. My investigative armamentarium includes outstanding mouse models of spotted fever and typhus rickettsioses and monocytotropic ehrlichioses, which lend themselves to the study of pathogenesis as well as immunity. The molecular studies of rickettsiae have focused on major immunodominant outer membrane proteins, including S-layer proteins, surface proteins with hydrophilic domains containing multiple repeat units and candidate adhesins. Recent data revealed that non-surface exposed T-cell stimulatory antigens shared among widely divergent rickettsiae provide significant crossprotection. The molecular studies of Ehrlichia chaffeensis, E. canis, and E. muris have focused on surface-exposed immuno-dominant glycoproteins and a multigene family of immunodominant 28 kDa surface proteins, and are now using proteomic and genomic approaches to identify protective antigens.

Other projects include the genomic sequencing of selected microorganisms, development of vaccines against E. canis and development of new diagnostic tests utilizing our patented genes sponsored by the Clayton Foundation, and a Fogarty training grant on emerging and reemerging rickettsial diseases in Mexico, Brazil, and Cameroon. The latter offers opportunities for field and laboratory work in tropical locations.

My research is greatly enhanced by collaborative efforts involving the molecular expertise of Drs. Xuejie Yu, Jere McBride and Donald Bouyer, the immunologic knowledge and skills of Drs. Nahed Ismail and Lynn Soong, the ultrastructural expertise of Dr. Vsevolod Popov, and the cell biology skills of Dr. Juan Olano including confocal microscopy and flow cytometry.

By virtue of the breadth and depth of this collaborative team and competitively funded projects, there are numerous opportunities for student rotation and dissertation projects in molecular microbiology, immunity and microbial pathogenesis. New initiatives include molecular countermeasures against bioterrorism by microbial agents and vector biology of tick- and flea-borne ehrlichial and rickettsial infections.

Selected Publications
  1. WALKER DH: Anthrax.. In: Guerrant RL, WALKER DH, Weller PF, editors. Tropical Infectious Diseases. Principles, Pathogens, and Practice. 2nd ed. Philadelphia (PA): Elsevier Churchill Livingstone, 448-453, 2006
  2. WALKER DH, Maguiña C, Minnick M:. Bartonelloses. In: Guerrant RL, WALKER DH, Weller PF, editors. Tropical Infectious Diseases. Principles, Pathogens, and Practice. 2nd ed. Philadelphia (PA): Elsevier Churchill Livingstone, 454-462, 2006
  3. Guerrant RL, WALKER DH, Weller PF, eds: Tropical Infectious Diseases: Principles, Pathogens, & Practice, 2nd Ed. Elsevier Churchill Livingstone, Philadelphia, PA, 2006
  4. WALKER DH: Principles of parasitism: host—parasite interactions. In: Guerrant RL, WALKER DH, Weller PF, editors. Tropical Infectious Diseases. Principles, Pathogens, and Practice. 2nd ed. Philadelphia (PA): Elsevier Churchill Livingstone, 1-12, 2006
  5. Sexton DJ, WALKER DH: Spotted fever group rickettsioses. In: Guerrant RL, WALKER DH, Weller PF, editors. Tropical Infectious Diseases. Principles, Pathogens, and Practice. 2nd ed. Philadelphia (PA): Elsevier Churchill Livingstone, 539-547, 2006
  6. Dumler JS, WALKER DH: Ehrlichioses and anaplasmosis. In: Guerrant RL, WALKER DH, Weller PF, editors. Tropical Infectious Diseases. Principles, Pathogens, and Practice. 2nd ed. Philadelphia (PA): Elsevier Churchill Livingstone. 564-573, 2006
  7. Olano JP, Peters CJ, WALKER. DH: Distinguishing tropical infectious diseases from bioterrorism. In: Guerrant RL, WALKER DH, Weller PF, editors. Tropical Infectious Diseases. Principles, Pathogens, and Practice. 2nd ed. Philadelphia (PA): Elsevier Churchill Livingstone, 1386-1399, 2006
  8. WALKER DH, Raoult D: Typhus group rickettsioses. In: Guerrant RL, WALKER DH, Weller PF, editors. Tropical Infectious Diseases. Principles, Pathogens, and Practice. 2nd ed. Philadelphia (PA): Elsevier Churchill Livingstone, 548-556, 2006
  9. Watt G, WALKER DH: Scrub typhus. In: Guerrant RL, WALKER DH, Weller PF, editors. Tropical Infectious Diseases. Principles, Pathogens, and Practice. 2nd ed. Philadelphia (PA): Elsevier Churchill Livingstone, 557-563, 2006
  10. Lai S, WALKER DH, Elghetany MT:Catastrophic antiphospholipid syndrome: a rare cause of disseminated microvascular thrombotic injury – a case report with pathological and molecular correlative studies. Pathol Int 55:144-149, 2005
  11. Labruna MB, Camargo LMA, Camargo EP, WALKER DH: Detection of a spotted fever group Rickettsia in the tick Haemaphysalis juxtakochi in Rondonia, Brazil. Vet Parasitol 127:169-174, 2005
  12. Valbuena G, WALKER DH: Changes in the adherens junctions of human endothelial cells infected with spotted fever group rickettsiae. Virchows Arch 446:379-382, 2005
  13. Stevenson HL, Labruna MB, Montenieri JA, Kosoy MY, Gage KL, WALKER, DH: Detection of Rickettsia felis in a New World flea species, Anomiopsyllus nuata (Siphonaptera: Ctenophthalmidae). J Med Entomol 42:163-167, 2005
  14. Zavala-Castro JE, Small M, Keng C, Bouyer DH, Zavala-Velázquez J, WALKER DH: Transcription of the Rickettsia felis ompA gene in naturally infected fleas. Am J Trop Med Hyg 73:662-666, 2005
  15. Whitworth T, Popov VL, Yu XJ, Walker DH, Bouyer DH: Expression of Rickettsia prowazekii pld or tlyC gene in Salmonella enterica serovar typhimurium mediates phagosomal escape. Infect Immun 73:6668-6673, 2005
  16. Mattner J, DeBord KL, Ismail N, Goff RD, Cantu C, III, Zhou D, Saint-Mezard P, Wang V, Gao Y, Yin N, Hoebe K, Schneewind O, WALKER DH, Beutler B, Teyton L, Savage PB, Bendelac A: Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 434:525-529, 2005
  17. Horta MC, Labruna MB, Sangioni LA, Vianna M, Gennari, SM, Galvao M, Mafra CL, Vidotto O, Schumaker T, Walker DH: Prevalence of antibodies to spotted fever group rickettsiae in humans and domestic animals in a Brazilian spotted fever-endemic area in the State of São Paulo, Brazil: serologic evidence for infection by Rickettsia rickettsii and another spotted fever group rickettsia. Am J Trop Med Hyg 71:93-97, 2004
  18. Valbuena G, Jordan JM, WALKER DH: T cells mediate cross-protective immunity between spotted group rickettsiae and spotted fever group rickettsiae. J Infect Dis 190:1221-1227, 2004
  19. Ndip L, Fokam E, Bouyer DH, Ndip R, Titanji PK, WALKER DH, McBride J: Detection of Rickettsia africae in patients and ticks along the coastal region of Cameroon. Am J Trop Med Hyg 71:363-366, 2004
  20. McLeod MP, Qin X, Karpathy SE, Gioia J, Highlander SK, Fox GE, McNeill TZ, Jiang H, Muzny D, Jacob LS, Hawes AC, Sodergren E, Gill R, Hume J, Morgan M, Fan G, Amin AG, Gibbs RA, Hong C, Yu XJ, WALKER DH, Weinstock GM: Complete genome sequence of Rickettsia typhi and comparison with sequences of other rickettsiae. J Bacteriol 186:5842-5855, 2004
  21. Feng H-M, Whitworth T, Olano JP, WALKER DH:.Fc-dependent polyclonal antibodies and antibodies to outer membrane proteins A and B, but not to lipopolysaccharide protect SCID mice against fatal Rickettsia conorii infection. Infect Immun 72:2222-2228, 2004
  22. Valbuena G, WALKER DH:. Expression of CX3CL1 (fractalkine) in mice with endothelial-target rickettsial infection of the spotted fever group. Virchows Arch 446:21-27, 2004
  23. Labruna MB, Bouyer DH, McBride JW, Camargo LMA, Camargo EP, WALKER DH: Molecular evidence for a spotted fever group Rickettsia species in the tick Amblyomma longirostre in Brazil. J Med Entomol 41:533-537, 2004
  24. Jang W-J, Kim J-H, Choi Y-J, Jung K-D, Lee S-H, Choi M-S, Kim I-S, WALKER DH, Park K-H: First serologic evidence of human spotted fever group rickettsiosis in Korea. J Clin Microbiol 42:2310-2313, 2004
  25. Dumler JS, WALKER DH: Rickettsia typhi (murine typhus). In: Principles and Practice of Infectious Diseases, 6th Ed. Mandell GL, Bennett JE, Dolin R, eds. Churchill Livingstone, Philadelphia, PA, 2306-2310, 2004
  26. WALKER DH, D. Raoult: Rickettsia rickettsii and other spotted fever group rickettsiae (Rocky Mountain spotted fever and other spotted fevers). In: Principles and Practice of Infectious Diseases 6th ed. Mandell GL, Bennett J, Dolin R,eds. Churchill Livingstone, Philadelphia, PA 2287-2294, 2004
  27. WALKER DH, Raoult D, Dumler JS, Marrie TJ: Rickettsial diseases. In: Harrison's Principles of Internal Medicine, 16th Ed., Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL, eds. McGraw-Hill, New York, NY, 999-1008, 2004
  28. WALKER DH, Dumler JS: Ehrlichia chaffeensis (human monocytotropic ehrlichiosis), Anaplasma phagocytophila (human granulocytotropic ehrlichiosis), and other ehrlichiae. In: Principles and Practice of Infectious Diseases, 6th Ed. Mandell GL, Bennett JE, and Dolin R, eds.Churchill Livingstone, Philadelphia, PA, 2310-2318, 2004
  29. Valbuena G, WALKER DH: Effect of blocking the CXCL9/10-CXCR3 chemokine system in the outcome of endothelial-target rickettsial infections. Am J Trop Med Hyg 71:393-399, 2004
  30. Calic SB, Galvão MAM, Bacellar F, Mafra CL, Rocha CMBM, Chamone CB, Leite RC, WALKER DH:. Human ehrlichioses in Brazil: first suspect cases. Braz J Infect Dis 8:256-262, 2004
  31. Raoult D, WALKER DH: Rickettsia prowazekii (epidemic or louse-borne typhus). In: Principles and Practice of Infectious Diseases 6th ed. Mandell GL, Bennett J, Dolin R,eds. Churchill Livingstone, Philadelphia, PA 2303-2306, 2004
  32. Labruna MB, Whitworth T, Bouyer DH, McBride J, Camargo LMA, Camargo EP, Popov V, WALKER DH: Rickettsia bellii and Rickettsia amblyommii in Amblyomma ticks from the state of Rondônia, Western Amazon, Brazil. J Med Entomol 41:1073-1081, 2004
  33. Feng H-M, WALKER DH: Mechanisms of immunity to Ehrlichia muris: a model of human monocytotropic ehrlichiosis. Infect Immun 72:966-971, 2004
  34. Ismail N, Soong L, Valbuena G, McBride JW, Olano JP, WALKER DH: . Overproduction of TNF-α by CD8+ type-1 cells and downregulation of IFN-γ production by CD4+ Th1 cells contribute to toxic shock-like syndrome in an animal model of fatal monocytotropic ehrlichioses. J Immunol 172:1786-1800, 2004
  35. Labruna MB, Whitworth T, Horta MC, Bouyer DH, McBride JW, Pinter A, Popov V, Gennari SM, WALKER DH: Rickettsia species infecting Amblyomma cooperi ticks from an area in the State of Sao Paulo, Brazil, where Brazilian spotted fever is endemic. J Clin Microbiol 42: 90-98, 2004
  36. Ndip LM, Bouyer DH, Travossos Da Rosa APA, Titan J, Tesh RB, WALKER DH:. Acute spotted fever rickettsiosis among febrile patients, Cameroon. Emerg Infect Dis 10:432-436, 2004
  37. Olano J, Feng HM, McBride JW, Wen G, WALKER DH: Histologic, serologic, and molecular analysis of persistent ehrlichiosis in a murine model. Am J Pathol 165:997-1006, 2004
  38. Feng H-M, Whitworth T, Popov V, WALKER DH: Effect of antibody on the rickettsia-host cell interaction. Infect Immun 72:3524-3530, 2004
  39. Alcantara VE, Gallardo EG, WALKER DH:.Typhus group rickettsial antibodies in rural Mexico. Emerg Infect Dis 10:549-550, 2004
  40. Galvão MAM, Lamounier JA, Bonomo E, Tropia MS, Rezende EG, Calic SB, Chamone CB, Machado MC, Otoni MEA, Leite RC, Caram C, Mafra CL, WALKER DH: Rickettsioses emergentes e reemergentes numa região endêmica do estado de Mina Gerais, Brazil. Cad. Saúde Pública 18:1593-1597, 2003
  41. WALKER DH: Fatal cardiac failure in a 7-month-old child. Pediatr Dev Pathol 6:582-584, 2003
  42. Li Z, Diaz-Montero CM, Yu X-J, Valbuena G, Olano JP, Feng H-M, WALKER DH:. Identification of CD8 T-lymphocyte epitopes in ompB of Rickettsia conorii. Infect Immun 71:3920-3926, 2003
  43. Olano JP, Masters E, Hogrefe W, WALKER DH: Human monocytotropic ehrlichiosis, Missouri. Emerg Infect Dis 9:1579-1586, 2003
  44. Zavala-Velazquez JE, Zavala-Castro J, Vado-Soliz I, Ruiz-Sosa JA, Moron C, Bouyer D, WALKER DH: Identification of Ctenocephalides felis fleas as the reservoir of Rickettsia felis, the agent of spotted fever rickettsioses in Yucatán Mexico. Vector Borne and Zoonotic Diseases 2:69-75, 2003
  45. Feng H-M, WALKER DH: Cross-protection between distantly related spotted fever group rickettsiae. Vaccine 21:3901-3905, 2003
  46. Lewin MR, Bouyer DH, WALKER DH, Musher DM: Rickettsia sibirica infection in members of scientific expeditions to northern Asia. Lancet 362:1201-1202, 2003
  47. McBride JW, Corstvet RE, Gaunt SD, Boudreaux C, Guedry T, WALKER DH: Kinetics of antibody response to Ehrlichia canis immunoreactive proteins. Infect Immun 71:2516-24, 2003
  48. Galvão MAM, Mafra CL, Chamone CB, Calic SB, Cesarino Fillho G, Olano JP, WALKER DH: Spotted fever rickettsiosis in Coronel Fabriciano, Minas Gerais state. Revista da Sociedade Brasileira de Medicina Tropical 36: 479-481, 2003
  49. WALKER DH, Bouyer DH: Rickettsia. In: Manual of Clinical Microbiology, 8th Ed. Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH, eds. American Society for Microbiology Press, Washington, D.C., 1005-1014, 2003
  50. Stenos J, Graves S, Popov VL, WALKER DH: Aponomma hydrosauri, the reptile-associated tick reservoir of Rickettsia honei on Flinders Island, Australia. Am J Trop Med Hyg 69:314-317, 2003
  51. Olano JP, Hogrefe W, Cullman L, Seaton B, WALKER DH: Clinical manifestations, epidemiology, and laboratory diagnosis of human monocytotropic ehrlichiosis in a commercial laboratory setting. Clin Diag Lab Immunol 10:891-896, 2003
  52. Valbuena G, Bradford W, WALKER DH: Expression analysis of the T-cell targeting chemokines CXCL9 and CXCL1 in mice and humans with endothelial infections caused by rickettsiae of the spotted fever group. Am J Pathol 163:1357-1369, 2003
  53. Galvao M, Dumler JS, Mafra CL, Calic SB, Chamone CB, Cesarino Filho G, Olano JP, WALKER DH: Fatal spotted fever rickettsiosis, Minas Gerais, Brazil. Emerg Infect Dis 9:1402-1405, 2003
  54. Long SW, Zhang X-F, Qi H, Standaert S, WALKER DH, Yu X-J. Antigenic variation of Ehrlichia chaffeensis resulting from differential expression of the 28-kilodalton protein gene family. Infect Immun 70:1824-1831, 2002
  55. Crocquet-Valdes PA, Diaz-Montero CM, Feng H-M, Li H, Barrett ADT, WALKER DH. Immunization with a portion of rickettsial outer membrane protein A stimulates protective immunity against spotted fever rickettsiosis. Vaccine 20:979-988, 2002
  56. Olano JP, WALKER DH. Human Ehrlichiosis. Med Clinics of N. Am. 86:375-392, 2002
  57. McBride JW, Ndip LM, Popov VL, WALKER DH. Identification and functional analysis of an immunoreactive DsbA-like thio-disulfide oxidoreductase of Ehrlichia spp. Infect Immun 70:2700-2703, 2002
  58. WALKER DH, Yu XJ: Rickettsia, orientia, ehrlichia and coxiella. Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever. In: Medical Microbiology. A guide to microbial infections: pathogenesis, immunity, laboratory diagnosis and control. 16th Ed. Greenwood D, Slack RCB, Peutherer JF, eds. Churchill Livingstone, New York, NY, 369-378, 2002
  59. Oliveira RP, Galvao MAM, Mafra CL, Chamone CB, Calic SB, Silva SU, WALKER DH. Rickettsia felis in Ctenocephalides spp. fleas, Brazil. Emerg Infect Dis 8:317-319, 2002
  60. Dumler JS, WALKER DH: Ehrlichioses. In: Essentials of Tropical Infectious Diseases. RL Guerrant, DH Walker, PF Weller, eds. Churchill Livingstone, Philadelphia, PA, 49:281-283, 2001
  61. Watt G, WALKER DH: Scrub Typhus. In: Essentials of Tropical Infectious Diseases. RL Guerrant, DH Walker, PF Weller, eds. Churchill Livingstone, Philadelphia, PA, 48:278-281, 2001
  62. Sotomayor EA, Popov VL, Feng H-M, WALKER DH: Animal model of fatal human monocytotropic ehrlichiosis. Am J Pathol 158:757-769, 2001
  63. Molina CP, WALKER DH: The Pathology of Community-acquired Pneumonia. In: Marrie T, ed. Community-acquired Pneumonia. T Marrie, ed. New York: Kluwer Academic/Plenum Publishers, 101-129, 2001
  64. John TJ, WALKER DH: Enterovirus Infections, Including Poliomyelitis. In: Essentials of Tropical Infectious Diseases. RL Guerrant, DH Walker, PF Weller, eds. Churchill Livingstone, Philadelphia, PA, 98:530-535, 2001
  65. WALKER DH: Typhus Group Rickettsioses. In: Essentials of Tropical Infectious Diseases. RL Guerrant, DH Walker, PF Weller, eds. Churchill Livingstone, Philadelphia, PA, 47:274-278, 2001
  66. WALKER DH: Anthrax. In: Essentials of Tropical Infectious Diseases. RL Guerrant, DH Walker, PF Weller, eds. Churchill Livingstone, Philadelphia, PA, 35:227-230, 2001
  67. McBride JW, Corstvet RE, Breitschwerdt EB, WALKER DH: Immunodiagnosis of Ehrlichia canis infection with recombinant proteins. J Clin Micro 39:315-322, 2001
  68. Guerrant RL, WALKER DH, Weller PF (eds): Essentials of Tropical Infectious Diseases. Churchill Livingstone, Philadelphia, PA, 2001
  69. Sexton DF, WALKER DH: Spotted Fever Group Rickettsioses. In: Essentials of Tropical Infectious Diseases. RL Guerrant, DH Walker, PF Weller, eds. Churchill Livingstone, Philadelphia, PA, 46:271-274, 2001
  70. WALKER DH, Guerra H, Maguiña C: Bartonelloses. In: Essentials of Tropical Infectious Diseases. RL Guerrant, DH Walker, PF Weller, eds. Churchill Livingstone, Philadelphia, PA, 36:230-233, 2001
  71. Billings AN, Feng H-M, Olano JP, WALKER DH: Rickettsial infection in murine models activates an early anti-rickettsial effect mediated by NK cells and associated with production of gamma interferon. Am J Trop Med Hyg 65:52-56, 2001
  72. Yu X-J, Zhang X-F, McBride JW, Zhang Y, WALKER DH: Phylogenetic relationships of Anaplasma marginale and ‘Ehrlichia platys’ to other Ehrlichia species determined by GroEL amino acid sequences. Int J Syst Evol Microbiol 51:1143-1146, 2001
  73. Schmaier AH, Srikanth S, Elghetany MT, Normolle D, Gokhale S, Feng H-M, WALKER DH: Hemostatic/fibrinolytic protein changes in C3H/HeN mice infected with Rickettsia conorii – A model for Rocky Mountain Spotted Fever. Thromb Haemost 86:871-879, 2001
  74. WALKER DH, Feng H-M, Popov VL: Rickettsial phospholipase A2 as a pathogenic mechanism in a model of cell injury by typhus and spotted fever group rickettsiae. Am J Trop Med Hyg 65:936-942, 2001
  75. Diaz CM, Feng HM, Crocquet-Valdes, Walker DH. Identification of protective components of two major outer membrane proteins of spotted fever group rickettsiae. Am J Trop Med Hyg 65:371-378, 2001
  76. Grinberg LM, Abramova FA, Yampolskaya OV, WALKER DH, Smith JH: Quantitative pathology of inhalational anthrax 1: quantitative microscopic findings. Mod Pathol 14:482-495, 2001
  77. Moron CL, Feng HM, Wear DJ, WALKER DH: Identification of the target cells of Orientia tsutsugamushi in human cases of scrub typhus. Mod Pathol 14:752-759, 2001
  78. Ventura KC, Hawkins H, Smith MB, WALKER DH: Fatal neonatal echovirus 6 infection: Autopsy case report and review of the literature. Mod Pathol 14:85-90, 2001
  79. WALKER DH, Olano JP, Feng H-M: Critical role of cytotoxic T lymphocytes in immune clearance of ricketsial infection. Infect Immun 69:1841-1846, 2001
  80. Moron CG, Bouyer DH, Yu X-J, Foil LD, Crocquet-Valdes P, Walker DH: Phylogenetic analysis of the rompB genes of Rickettsia felis and Rickettsia prowazekii European human and North American flying-squirrel strains. Am J Trop Med Hyg 62:598-603, 2001
  81. Bouyer DH, Stenos J, Crocquet-Valdes P, Moron CG, Popov VL, Zavala-Velazquez JE, Foil LD, Stothard DR, Azad AF and Walker DH: Rickettsia felis: molecular characterization of a new member of the spotted fever group. Int J Syst Evol Microbiol 51:339-347, 2001
  82. Zavala-Velazquez JE, Ruiz-Sosa JA, Sánchez-Elias RA, Becerra-Carmona G, Walker DH: Rickettsia felis rickettsiosis in Yucatán. The Lancet 9235:1079-1080, 2000
  83. Yu X-J, McBride JW, Diaz CM, WALKER DH: Molecular cloning and characterization of the 120-kilodalton protein gene of Ehrlichia canis and application of the recombinant 120-kilodalton protein for serodiagnosis of canine ehrlichiosis. J Clin Micro 38: 369-374, 2000
  84. McBride JW, Yu XJ, WALKER DH: A conserved, transcriptionally active p28 multigene locus of Ehrlichia canis. Gene 254:245-252, 2000
  85. McBride JW, Yu X-J, WALKER DH: Glycosylation of homologous immunodominant proteins of Ehrlichia chaffeensis and Ehrlichia canis. Infect Immun 68:13-18, 2000
  86. WALKER DH: Rickettsial diseases including ehrlichioses. In: Concise Oxford Textbook of Medicine. Ledingham JGG and Warrell DA, eds. Oxford University Press, New York, NY, 1691-1698, 2000
  87. WALKER DH, Popov VL, Feng H-M: Establishment of a novel endothelial target mouse model of a typhus group rickettsiosis: evidence of critical roles for gamma interferon and CD8 T lymphocytes. Lab Invest 80:1361-1372, 2000
  88. Feng HM, WALKER DH: Mechanisms of intracellular killing of Rickettsia conorii in infected human endothelial cells, hepatocytes, and macrophages. Infect Immun 68:6729-6736, 2000
  89. WALKER DH, Raoult D: Rickettsia rickettsii and other spotted fever group rickettsiae (Rocky Mountain spotted fever and other spotted fevers). In: Principles and Practice of Infectious Diseases. Mandell GL, Bennett JE, and Dolin R, eds. Churchill Livingstone, New York, NY, 175:2035-2042, 2000
  90. Yu XJ, McBride JW, Zhang XF, WALKER DH: Characterization of the complete transcriptionally active Ehrlichia chaffeensis 28 kDa outer membrane protein multigene family. Gene 248:59-68, 2000
  91. Popov VL, Yu X-J, WALKER DH: The 120-kDa outer membrane protein of Ehrlichia chaffeensis: preferential expression on dense-core cells and gene expression in Escherichia coli associated with attachment and entry. Microbial Pathogen 28:71-80, 2000
  92. Stenos J, WALKER DH: The rickettsial outer membrane protein A and B genes of Rickettsia australis, the most divergent rickettsia of the spotted fever group. Int J Syst Bacteriol 50:1761-1766, 2000
  93. McBride JW, Yu X-J, WALKER DH: Molecular characterization of a new 28-kilodalton protein gene and a multigene locus encoding five homologous 28-kilodalton immunodominant outer membrane proteins of Ehrlichia canis. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 43-47, 1999
  94. Moron CG, Yu X-J, Crocquet-Valdes P, Walker DH: Sequence analysis of the romp B gene of Rickettsia prowazekii isolated from flying squirrels. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 48-51, 1999
  95. Rudakov NV, Samoilenko IE, Yakimenko VV, Reshetnikova TA, Chpynov SN, WALKER DH: The re-emergence of Siberian tick typhus: field and experimental observations. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 269-273, 1999
  96. Olano JP, Masters E, Cullman L, Hogrefe W, Yu X-J, WALKER DH: Human monocytotropic ehrlichiosis (HME): Epidemiological, clinical and laboratory diagnosis of a newly emergent infection in the United States. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 262-268, 1999
  97. Galvao M, Chamone CB, Calic SB, Machado MC, Otoni MEA, Dietze R, Moron C, Feng H-M, Olano JP, WALKER DH: Serologic evidence of spotted fever group Rickettsia in Novo Cruzeiro Municipality-Minas Gerais State-Brazil. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 240-243, 1999
  98. Woods GL, Schnadig V, WALKER DH, Winn W: Pathology of Infectious Diseases: Clinical Cases. Butterworth Heinemann, 1999
  99. Olano JP, WALKER DH: Ehrlichial Infections. In: Clinical Dermatology. Demis DJ, ed. Lippincott Williams & Wilkins, Philadelphia, PA, 3:1-10, 15-2, 1999
  100. WALKER DH: Rickettsial Infections. In: Clinical Dermatology. Demis DJ, ed. Lippincott Williams & Wilkins, Philadelphia, PA, 3:1-18, 15-1, 1999
  101. McGinnis MR, Lemon SM, WALKER DH, de Hoog GS, Haase G. Fatal cerebritis caused by a new species of Cladophialophora. Studies in Mycology 43:166-171, 1999
  102. Feng H-M, WALKER DH: Mechanisms of immunity to Ehrlichia chaffeensis in mice. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 145-150, 1999
  103. Diaz M, Feng H-M, WALKER DH: Rickettsia conorii antigen presentation to CD8 T-lymphocytes by a murine endothelial cell line. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 123-127, 1999
  104. Bouyer DH, Stenos J, Crocquet-Valdes P, Foil L, WALKER DH: The identification and characterization of a previously undiscovered rOmpA encoding gene in Rickettsia felis. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 11-15, 1999
  105. WALKER DH, Hudnall SD, Szaniawski WK, Feng HM: Monoclonal antibody-based immunohistochemical diagnosis of rickettsialpox: The macrophage is the principal target. Mod Pathol 12:529-533, 1999
  106. McBride JW, Yu X-J, Walker DH: Molecular cloning of the gene for a conserved major immunoreactive 28-kilodalton protein of Ehrlichia canis: a potential serodiagnostic antigen. Clin Diagn Lab Immunol 6:392-399, 1999
  107. Yu X-J, McBride JW, WALKER DH: Genetic diversity of the 28-kilodalton outer membrane protein gene in human isolates of Ehrlichia chaffeensis. J Clin Microbiol 37:1137-1143, 1999
  108. Carpenter CF, Gandhi TK, Kong LK, Corey GR, Chen S-M, WALKER DH, Dumler JS, Breitschwerdt E, Hegarty B, Sexton DJ. The incidence of ehrlichial and rickettsial infection in patients with unexplained fever and recent history of tick bite in central North Carolina. J Infect Dis 180:900-903, 1999
  109. Zavala-Velazquez JE, Ruiz-Sosa J, Vado-Solis I, Billings AN, WALKER DH: Serologic study of the prevalence of rickettsiosis in Yucatán: Evidence for a prevalent spotted fever group rickettsiosis. Am J Trop Med Hyg 61:405-408, 1999
  110. Yu X-J, Crocquet-Valdes PA, Cullman LC, Popov VL, Walker DH: Comparison of Ehrlichia chaffeensis recombinant proteins for serologic diagnosis of human monocytotropic ehrlichiosis. J Clin Micro 37:2568-2575, 1999
  111. WALKER DH, Zavala-Velazquez JE, Ramirez G, Olano JP: Emerging infectious diseases in the Americas. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 274-277, 1999
  112. WALKER DH, Crocquet-Valdes PA, Feng H-M: Intracellular anti-rickettsial mechanisms of chemokine- and cytokine-activated human macrophages and hepatocytes. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 189-194, 1999
  113. WALKER DH: Rickettsial infections. In: Clinical Dermatology. Demis DJ, ed. JB Lippincott Williams & Wilkins, Philadelphia, PA, (15:1)1-18, 1999
  114. John TJ, WALKER DH: Enterovirus infections, including poliomyelitis. In: Tropical Infectious Diseases, Principles, Pathogens, and Practice. RL Guerrant, DH Walker, PF Weller eds. Churchill Livingstone, Philadelphia, PA, 105:1123-1132, 1999
  115. Olano JP, Krogstad DJ, Guerrant RL, Weller PF, WALKER DH: Principles of parasitism: host-parasite interactions. In: Tropical Infectious Diseases, Principles, Pathogens, and Practice. RL Guerrant, DH Walker, PF Weller eds. Churchill Livingstone, Philadelphia, PA, 1:3-15, 1999
  116. Yu X-J, McBride JW, WALKER DH: Characterization of the genus-common outer membrane proteins in Ehrlichia. In: Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. Raoult D, Brouqui P, eds. Elsevier, Paris, France, 103-108, 1999
  117. Billings AN, Teltow G, Weaver SC, WALKER DH: Molecular characterization of a novel Rickettsia species from Ixodes scapularis in Texas. Emerg Infect Dis 4:305-309, 1998
  118. Billings AN, Yu X-J, Teel PD, WALKER DH: Detection of a spotted fever group rickettsia in Amblyomma cajennense (Acari: Ixodidae) in south Texas. J Med Entomol 35:474-478, 1998
  119. Stenos J, Roux V, WALKER DH, Raoult D: Rickettsia honei sp. nov., the aetiologic agent of Flinders Island spotted fever in Australia. Inter J Syst Bacteriol 48:1399-1404, 1998
  120. Billings AN, Rawlings JA, WALKER DH: Tick-borne diseases in Texas: a 10-year retrospective examination of cases. Tex Med 94:66-76, 1998
  121. Popov VL, Han VC, Chen S-M, Dumler JS, Feng H-M, Andreadis TG, Tesh RB, WALKER DH: Ultrastructural differentiation of the genogroups in the genus Ehrlichia. J Med Microbiol 47:235-251, 1998
  122. Sexton DJ, Corey GR, Carpenter C, Kong LQ, Gandhi T, Breitschwerdt E, Hegarty B, Chen S-M, Feng H-M, Yu X-J, Olano J, WALKER DH, Dumler JS: Dual infection with Ehrlichia chaffeensis and a spotted fever group rickettsia: A case report. Emerg Infect Dis 4:311-316, 1998
  123. WALKER DH: Cat scratch disease, bacillary angiomatosis, and other bartonelloses. In: Mechanisms of Microbial Disease, 3rd Edition, Schaechter M, Engleberg NC, Eisenstein BI, Medoff G, eds. Williams & Wilkins, Baltimore, MD, 26:257-260, 1998
  124. WALKER DH, Sexton DJ: Rickettsia rickettsii. In: Antimicrobial Chemotherapy. Yu VL, Merigan TC, Barriere SL, eds. Williams & Wilkins Publishers, Baltimore, MD, Part C, 562-568, 1998
  125. WALKER DH: Rocky Mountain spotted fever and other rickettsioses. In: Mechanisms of Microbial Disease 3rd Ed. Schaechter M, Engleberg NC, Eisenstein B, Medoff G, eds. Williams and Wilkins Publishers, Baltimore, MD, 268-274, 1998
  126. WALKER DH: Emerging human ehrlichioses: recently recognized, widely distributed, life-threatening tick-borne diseases. In: Emerging Infections I. 1st Edition, Scheld WM, Armstrong D, Hughes JM, eds. ASM Press, Washington, DC, 6:81-91, 1998
  127. Durack DT, WALKER DH: Rickettsial infections. In: Internal Medicine. 5th Edition, Stein JH, Eisenberg JM, Hutton JJ, Klippel JH, Kohler PO, LaRusso NF, O'Rourke RA, Reynolds HY, Samuels MA, Sande MA, Zvaifler NJ, eds. Mosby Press, Baltimore, MD, 259:1541-1546, 1998
  128. WALKER DH: Rocky Mountain spotted fever and other rickettsioses In: Mechanisms of Microbial Disease, 3rd Edition, Schaechter M, Engleberg NC, Eisenstein BI, Medoff G, eds. Williams & Wilkins, Baltimore, MD, 28:268-274, 1998
  129. Li H, WALKER DH: rOmpA is a critical protein for the adhesion of Rickettsia rickettsii to host cells. Microbial Pathogen 24:289-298, 1998
  130. WALKER DH, Dumler JS: Rickettsial infections. In: Pathology of Infectious Diseases, Vol. I. Connor DH, Chandler FW, Schwartz D, Manz HJ, Lack EE, eds. Appleton & Lange, Inc, Stamford, CT, 85:789-799, 1997
  131. Dumler JS, WALKER DH: Ehrlichial infections. In: Pathology of Infectious Diseases, Vol. I. Connor DH, Chandler FW, Schwartz D, Manz HJ, Lack EE, eds. Appleton & Lange, Inc, Stamford, CT, 56:543-548, 1997
  132. Chen S-M, Yu X-J, Popov VL, Westerman EL, Hamilton FG, WALKER DH: Genetic and antigenic diversity of Ehrlichia chaffeensis: comparative analysis of a novel human strain from Oklahoma and previously isolated strains. J Infect Dis 175:856-863, 1997
  133. Schuenke KL, WALKER DH: Vaccine development for rickettsial infections: Rocky Mountain spotted fever, epidemic typhus, and scrub typhus. In: New Generation Vaccines, 2nd Edition, Revised and Expanded, Levine MM, Woodrow GC, Kaper JB, Cobon GS, eds. Marcel Dekker, Inc., New York, NY, 37:527-543, 1997
  134. Feng H-M, Popov VL, Yuoh G, WALKER DH: Role of T lymphocyte subsets in immunity to spotted fever group rickettsiae. J Immunol 158:5314-5320, 1997
  135. Yu X-J, Crocquet-Valdes PA, WALKER DH: Cloning and sequencing of the gene for a 120-kDa immunodominant protein of Ehrlichia chaffeensis. Gene 184:149-154, 1997
  136. WALKER DH, Popov VL, Crocquet-Valdes PA, Welsh CJR, Feng H-M: Cytokine-induced, nitric oxide-dependent, intracellular antirickettsial activity of mouse endothelial cells. Lab Invest 76:129-138, 1997
  137. Stenos J, Ross B, Feng H-M, Crocquet-Valdes P, WALKER DH: Protein characterization of Australian spotted fever group rickettsiae and monoclonal antibody typing of Rickettsia honei. J Clin Microbiol 35:261-263, 1997
  138. WALKER DH, Dumler JS: Human monocytic and granulocytic ehrlichioses: Discovery and diagnosis of emerging tick-borne infections and the critical role of the Pathologists. Arch Pathol Lab Med. 121:785-791, 1997
  139. WALKER DH, Feng H-M, Ladner S, Billings AN, Zaki SR, Wear DJ, Hightower B: Immunohistochemical diagnosis of typhus rickettsioses using an anti-lipopolysaccharide monoclonal antibody. Mod Pathol 10:1038-1042, 1997
  140. Chen S-M, Cullman LC, WALKER DH: Western immunoblotting analysis of the antibody responses of patients with human monocytotropic ehrlichiosis to different strains of Ehrlichia chaffeensis and Ehrlichia canis. Clin Diagn Lab Immunol 4:731-735, 1997
  141. Yu X-J, WALKER DH: Sequence and characterization of an Ehrlichia chaffeensis gene encoding 314 amino acids highly homologous to the NAD A enzyme. FEMS Letters 154:53-58, 1997
  142. Ghorbani RP, Ghorbani AJ, Jain MK, WALKER DH: A case of scrub typhus probably acquired in Africa. Clin Infect Dis 25:1473-1474, 1997
  143. Yu X-J, Piesman JF, Olson JG, WALKER DH: Short report: Geographic distribution of different genetic types of Ehrlichia chaffeensis. Am J Trop Med Hyg. 56:679-680, 1997
  144. Angeloni VL, Keller RA, WALKER DH: Rickettsialpox-like illness in a traveler. Military Med 162:636-639, 1997
  145. WALKER DH, Gage KL: Rickettsia, orientia, ehrlichia and coxiella.. In: Medical Microbiology, A guide to microbial infections: pathogenesis, immunity, laboratory diagnosis and control. 15th Ed. Greenwood D, Slack R, Peutherer J, eds. Churchill Livingstone, New York, NY, 371-380, 1997
  146. WALKER DH, Popov VL, Welsh CJR, Feng H-M: Mechanisms of rickettsial killing within cytokine-stimulated endothelial cells. In: Rickettsiae and Rickettsial Diseases. Kazar J, Toman R, eds. Slovak Academy of Sciences, Bratislava, Slovak Republic, 51-56, 1996
  147. Feng H-M, Popov VL, Billings A, Yuoh G, WALKER DH: Role of T-lymphocyte subsets in immunity to SFG rickettsiae. In: Rickettsiae and Rickettsial Diseases. Kazar J, Toman R, eds. Slovak Academy of Sciences, Bratislava, Slovak Republic, 255-260, 1996
  148. WALKER DH: Advances in understanding of typhus group rickettsial infections. In: Rickettsiae and Rickettsial Diseases. Kazar J, Toman R, eds. Slovak Academy of Sciences, Bratislava, Slovak Republic, 16-27, 1996
  149. Zavala-Velazquez JE, Yu X-J, WALKER DH: Unrecognized spotted fever group rickettsiosis masquerading as dengue fever in Mexico. Am J Trop Med Hyg 55:157-159, 1996
  150. WALKER DH: Rickettsiae. In: Medical Microbiology, Fourth edition, Baron S, ed. The University of Texas Medical Branch, Galveston, TX, 38:487-501, 1996
  151. Landry GA, WALKER DH: Ehrlichiosis: an emerging infectious disease. In: A Practical Approach to Infectious Diseases, Fourth Edition. Reese RE, Betts RF, eds. Little, Brown and Company, Appendix A:1399-1405, 1996
  152. Woods GL, WALKER DH: Chlamydial, rickettsial, and mycoplasmal infections. In: Clinical Diagnosis and Management by Laboratory Methods, Nineteenth Edition. Henry JB, ed. WB Saunders Company, 47:1115-1131, 1996
  153. Barenfanger J, Patel PG, Dumler JS, WALKER DH: Identifying human ehrlichiosis. Lab Med 27:372-374, 1996
  154. Chen S-M, Popov VL, Westerman EL, Hamilton FG, Dumler JS, Feng H-M, WALKER DH: Antigenic diversity among strains of Ehrlichia chaffeensis. In: Rickettsiae and Rickettsial Diseases, Kazar J, Toman R, eds. Slovak Academy of Sciences, Bratislava, Slovak Republic, 329-334, 1996
  155. Radulovic S, Feng H-M, Morovic M, Djelalija B, Popov V, Crocquet-Valdes P, WALKER DH: Isolation of Rickettsia akari from a patient in a region where Mediterranean spotted fever is endemic. Clin Infect Dis 22:216-220, 1996
  156. WALKER DH, Barbour AG, Oliver JH, Lane RS, Dumler JS, Dennis DT, Persing DH, Azad AF, McSweegan E: Emerging bacterial zoonotic and vector-borne diseases: Ecological and epidemiological factors. JAMA 275:463-469, 1996
  157. Yu X-J, Crocquet-Valdes P, Cullman LC, Piesman JF, Olson JG, WALKER DH: Genetic diversity of a 120-kDa immunodominant protein of Ehrlichia chaffeensis: a potential recombinant diagnostic tool. In: Rickettsiae and Rickettsial Diseases. Kazar J, Toman R, eds. Slovak Academy of Sciences, Bratislava, Slovak Republic, 324-328, 1996
  158. Chen S-M, Popov V, Feng H-M, WALKER DH: Analysis and ultrastructural localization of Ehrlichia chaffeensis proteins with monoclonal antibodies. Am J Trop Med Hyg 54:405-412, 1996
  159. WALKER DH: Rickettsiae. In: Medical Microbiology, 4th Edition. Baron S, ed. The University of Texas Medical Branch, Galveston, TX, 487-501, 1996
  160. Yu X-J, Crocquet-Valdes P, Cullman LC, WALKER DH: The recombinant 120-kilodalton protein of Ehrlichia chaffeensis, a potential diagnostic tool. J Clin Microbiol 34:2853-2855, 1996
  161. Liu Q-H, Chen G-Y, Jin Y, Te M, Niu L-C, Dong S-P, WALKER DH: Evidence for a high prevalence of spotted fever group rickettsial infections in diverse ecologic zones of Inner Mongolia. Epidemiol Infect 115:177-183, 1995
  162. WALKER DH: Rickettsial Disease. In: Oxford Textbook of Medicine, Third Edition. Warrell DA, ed. Oxford University Press, Oxford, 7.11.37:728-739, 1995
  163. WALKER DH, Dumler JS: Ehrlichia chaffeensis (human ehrlichiosis) and other ehrlichiae. In: Principles and Practice of Infectious Diseases, Fourth Edition. Mandell GL, Bennett JE, Dolin R, eds. Churchill Livingstone Inc, New York, NY, 1747-1752, 1995
  164. Chen S-M, Popov V, Feng H-M, Wen J, WALKER DH: Cultivation of Ehrlichia chaffeensis in mouse embryo, Vero, BGM, and L929 cells and study of Ehrlichia-induced cytopathic effect and plaque formation. Infect Immun 63:647-655, 1995
  165. Popov VL, Chen S-M, Feng H-M, WALKER DH: Ultrastructural variation of cultured Ehrlichia chaffeensis. J Med Microbiol 43:411-421, 1995
  166. Hove MGM, WALKER DH: Persistence of rickettsiae in the partially viable gangrenous margins of amputated extremities 5 to 7 weeks after onset of Rocky Mountain spotted fever. Arch Pathol Lab Med 119:429-431, 1995
  167. WALKER DH, Feng H-M, Saada JI, Crocquet-Valdes P, Radulovic S, Popov VL, Manor E: Comparative antigenic analysis of spotted fever group rickettsiae from Israel and other closely related organisms. Am J Trop Med Hyg 52:569-576, 1995
  168. Dumler JS, Chen S-M, Asanovich K, Trigiani E, Popov VL, WALKER DH: Isolation and characterization of a new strain of Ehrlichia chaffeensis from a patient with near-fatal monocytic ehrlichiosis. J Clin Microbiol 33:1704-1711, 1995
  169. WALKER DH, Dumler JS: Rickettsiae: Rickettsiae: Scrub typhus. In: Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections, Seventh Edition. Lennette DA, ed. American Public Health Association, 39:571-574, 1995
  170. WALKER DH, Dumler JS: Rickettsiae: Spotted fever and typhus group rickettsiae. In: Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections, Seventh Edition. Lennette DA, ed. American Public Health Association, 40:575-582, 1995
  171. WALKER DH, Dumler, JS: Rickettsial and chlamydial diseases. In: Damjanov I, Linder J, eds. Anderson’s Pathology. 10th ed. Vol. 1. Chicago (IL): Mosby Year Book, Inc. p. 866-885. Mosby Company, St. Louis, MO, 335-344, 1995
  172. Dumler JS, WALKER DH: Rickettsiae: Coxiella burnetii. In: Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections, Seventh Edition. Lennette DA, ed. American Public Health Association, 38:565-570, 1995
  173. Woodward TE, Sexton DJ, WALKER DH: Cutaneous manifestations of rickettsial infections. In: Atlas of Infectious Diseases, Skin, Soft Tissue, Bone and Joint Infections, Volume 2, Chapter 9. Mandell GL, Stevens D, eds. Current Medicine, Philadelphia, PA, 9.0-9.13, 1995
  174. WALKER DH, Dumler JS: Rickettsial and chlamydial diseases. In: Anderson's Pathology, 10th Edition, Damjanov I, Linder J, eds. Mosby Year Book, Inc. Chicago, IL, 866-885, 1995
  175. WALKER DH, Dumler JS: Rickettsial and chlamydial diseases. In: Anderson's Pathology, Tenth Edition, Vol. 1. Damjanov I, Linder J, eds. Mosby Year Book, Inc., Chicago, IL, 35:866-885, 1995
  176. WALKER DH, Dasch G: Classification and identification of Chlamydia, Rickettsia, and related bacteria. In: Manual of Clinical Microbiology, Sixth Edition. Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH, eds. American Society for Microbiology, Washington, D.C., 665-668, 1995
  177. Chen S-M, Dumler JS, Bakken JS, WALKER DH: Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease. J Clin Microbiol 32:589-595, 1994
  178. Chen S-M, Dumler JS, Feng H-M, WALKER DH: Identification of the antigenic constituents of Ehrlichia chaffeensis. Am J Trop Med Hyg 50:52-58, 1994
  179. WALKER DH, Popov VL, Wen J, Feng HM: Rickettsia conorii infection of C3H/HeN mice: a model of endothelial-target rickettsiosis. Lab Invest 70:358-368, 1994
  180. Crocquet-Valdes PA, Weiss K, WALKER DH: Sequence analysis of the 190-kDa antigen-encoding gene of Rickettsia conorii (Malish 7 strain). Gene 140:115-119, 1994
  181. WALKER DH: Mycoplasmal, chlamydial, and rickettsial pneumonias. In: Pulmonary Pathology, Second Edition. Dail DH, Hammer SP, eds. Springer-Verlag, New York, NY, 465-474, 1994
  182. Winn WC Jr, WALKER DH: Viral infections. In: Pulmonary Pathology, Second Edition. Dail DH, Hammar SP, eds. Springer-Verlag, New York, NY, 429-464, 1994
  183. WALKER DH, Dumler JS, Radulovic S: Spotted fevers and rickettsialpox. In: Infectious Diseases: A Modern Treatise of Infectious Processes, Fifth Edition. Hoeprich PD, Jordan MC, Ronald AL, eds. JB Lippincott Company, Philadelphia, PA, 969-978, 1994
  184. Dumler JS, WALKER DH: Diagnostic tests for Rocky Mountain spotted fever and other rickettsias. In: Dermatologic Clinics, Vol. 12. Dudlick B, Rapini RP, eds. WB Saunders Co, Philadelphia, PA, 25-36, 1994
  185. Williams WJ, Radulovic S, Dasch GA, Lindstrom J, Kelly DJ, Oster CN, WALKER DH: Identification of Rickettsia conorii infection by a polymerase chain reaction in a soldier returning from Somalia. Clin Infect Dis 19:93-99, 1994
  186. Radulovic S, Feng H-M, Crocquet-Valdes P, Morovic M, Dzelalija B, WALKER DH: Antigen-capture enzyme immunoassay: a comparison with other methods for the detection of spotted fever group rickettsiae in ticks. Am J Trop Med Hyg 50:359-364, 1994
  187. Trilar T, Radulovic S, and WALKER DH: Identification of a natural cycle involving Rickettsia typhi infection of Monopsyllus sciurorum sciurorum fleas from the nest of the fat dormouse (Glis glis). Eur J Epidemiol 10:757-762, 1994
  188. Bakken JS, Dumler JS, Chen S-M, Eckman MR, Van Etta LL, WALKER DH: Human granulocytic ehrlichiosis in the upper midwest United States. A new species emerging? JAMA 272:212-218, 1994
  189. Schuenke K, WALKER DH: Cloning, sequencing, and expression of the gene coding for an antigenic 120-kilodalton protein of Rickettsia conorii. Infect Immun 62:904-909, 1994
  190. Uchiyama T, Uchida T, WALKER DH: Analysis of major surface polypeptides of Rickettsia japonica. Microbiol Immunol 38:575-579, 1994
  191. Uchiyama T, Uchida T, Wen JW, WALKER DH: Demonstration of heat-labile and heat-stable epitopes of Rickettsia japonica on ultrathin sections. Lab Invest 71:432-437, 1994
  192. Feng H-M, Popov VL, WALKER DH: Depletion of gamma interferon and tumor necrosis factor alpha in mice with Rickettsia conorii-infected endothelium: impairment of rickettsicidal nitric oxide production resulting in fatal, overwhelming rickettsial disease. Infect Immun 62:1952-1960, 1994
  193. Abramova FA, Grinberg LM, Yampolskaya OV, WALKER DH: Pathology of inhalational anthrax in 42 cases from the Sverdlovsk outbreak of 1979. Proc Natl Acad Sci USA 90:2291-2294, 1993
  194. WALKER DH: Rickettsiae. In: Diagnostic Pathology of Infectious Diseases. Woods GL, Gutierrez Y, eds. Lea and Febiger, Philadelphia, PA, 194-213, 1993
  195. Dumler JS, Sutker WL, WALKER DH: Persistent infection with Ehrlichia chaffeensis. Clin Infect Dis 17:903-905, 1993
  196. Kirkland KB, Marcom PK, Sexton DJ, Dumler JS, WALKER DH: Rocky Mountain spotted fever complicated by gangrene: report of six cases and review. Clin Infect Dis 16:629-634, 1993
  197. Dumler JS, Dawson JE, WALKER DH: Human ehrlichiosis: hematopathology and immunohistologic detection of Ehrlichia chaffeensis. Hum Pathol 24:391-396, 1993
  198. Feng H-M, Wen J, WALKER DH: Rickettsia australis infection: a murine model of a highly invasive vasculopathic rickettsiosis. Am J Pathology 142:1471-1482, 1993
  199. Radulovic S, WALKER DH, Weiss K, Dzelalija B, Morovic M: Prevalence of antibodies to spotted fever group rickettsiae along the Eastern Coast of the Adriatic Sea. J Clin Microbiol 31:2225-2227, 1993
  200. Sexton DJ, Muniz M, Corey GR, Breitschwerdt EB, Hegarty BC, Dumler JS, WALKER DH, Pecanha PM, Dietze R: Brazilian spotted fever in Espirito Santo, Brazil: description of a focus of infection in a new endemic region. Am J Trop Med Hyg 49:222-226, 1993
  201. Feng H-M, WALKER DH: Interferon-δ and tumor necrosis factor-α exert their antirickettsial effect via induction of synthesis of nitric oxide. Am J Pathol 143:1016-1023, 1993
  202. Herrero JI, Ruiz R, WALKER DH: La técnica de Western immunoblotting en situaciones atípicas de infección por Rickettsia conorii. Presentación de 2 casos. Enferm Infecc Microbiol Clin 11:139-142, 1993
  203. Radulovic S, Speed R, Feng H-M, Taylor C, WALKER DH: EIA with species-specific monoclonal antibodies: a novel seroepidemiologic tool for determination of the etiologic agent of spotted fever rickettsiosis. J Infect Dis 168:1292-1295, 1993
  204. Herrero-Herrero JI, Ruiz-Beltrán R, WALKER DH: Antigens of Rickettsia conorii recognized by seropositive healthy people from Salamanca (Central-West Spain). Eur J Epidemiol 9:59-63, 1993
  205. Kaplowitz LG, WALKER DH: Rocky Mountain spotted fever and critical care. In: Principles of Critical Care Medicine. Hall JB, Schmidt GA, Wood LDH, eds. McGraw-Hill, Inc., New York, NY, 1368-1372, 1992
  206. WALKER DH, Murphy FA: Infectious diseases in developing countries. In: Global Infectious Diseases: Prevention, Control, and Eradication. WALKER DH, ed. Springer-Verlag, New York, NY, 1-3, 1992
  207. Li H, WALKER DH: Characterization of rickettsial attachment to host cells by flow cytometry. Infect Immun 60:2030-2035, 1992
  208. WALKER DH, Liu QH, Yu XJ, Han L, Taylor C, Feng HM: Antigenic diversity of Rickettsia conorii. Am J Trop Med Hyg 47:78-86, 1992
  209. WALKER DH (ed): Global Infectious Diseases: Prevention, Control and Eradication. New York; Springer-Verlag Wien, 1992
  210. Uchida T, Uchiyama T, Kumano K, WALKER DH: Rickettsia japonica sp. nov., the etiological agent of spotted fever group rickettsiosis in Japan. Int J Syst Bacteriol 42:303-305, 1992
  211. Herrero-Herrero JI, WALKER DH, Ruiz-Beltrán R: Use of Western blot to analyze the reactivity of sera from patients with Mediterranean spotted fever. Eur J Clin Microbiol Infect Dis 11:939-942, 1992
  212. WALKER DH, Watkins NG, Dumler JS, Vishwanath S: Experimental skin lesion (tache noire) in guinea-pigs after intradermal inoculation of Rickettsia conorii. Immunol Infect Dis 2:51-59, 1992
  213. WALKER DH: Rickettsial diseases: from epidemiology to molecules, the pathway toward disease control. In: Global Infectious Diseases: Prevention, Control, and Eradication. WALKER DH, ed. Springer-Verlag, New York, NY, 75-86, 1992
  214. Brouqui P, Dumler JS, Raoult D, WALKER DH: Antigenic characterization of ehrlichiae: protein immunoblotting of Ehrlichia canis, Ehrlichia sennetsu, and Ehrlichia risticii. J Clin Microbiol 30:1062-1066, 1992
  215. Dumler JS, Taylor JP, WALKER DH: Clinical and laboratory features of murine typhus in South Texas, 1980 through 1987. JAMA 266:1365-1370, 1991
  216. WALKER DH, Fishbein DB: Epidemiology of rickettsial diseases. In: Rickettsiae and Rickettsial Diseases. Kazar J, Raoult D, eds. Publishing House of the Slovak Academy of Sciences, Bratislava, Slovak Republic, 370-382, 1991
  217. Uchida T, Uchiyama T, Koyama AH, Yu XJ, WALKER DH, Funato T, Kitamura Y: Isolation and identification of Rickettsia japonica, causative agent of spotted fever group rickettsial infections in Japan. In: Rickettsiae and Rickettsial Diseases. Kazar J, Raoult D, eds. Publishing House of the Slovak Academy of Sciences, Bratislava, Slovak Republic, 389-395, 1991
  218. Uchiyama T, Uchida T, WALKER DH: Analysis of antigens of Rickettsia japonica with species-specific monoclonal antibodies. In: Rickettsiae and Rickettsial Diseases. Kazar J, Raoult D, eds. Publishing House of the Slovak Academy of Sciences, Bratislava, Slovak Republic, 396-400, 1991
  219. Weber DJ, WALKER DH: Rocky Mountain spotted fever. In: Infectious Disease Clinics of North America, Diseases Transmitted from Animals to Man. Weinberg AN, Weber DJ, eds. WB Saunders Co, Philadelphia, PA, 19-35, 1991
  220. Uchiyama T, Uchida T, WALKER DH: Species-specific monoclonal antibodies to Rickettsia japonica, a newly identified spotted fever group rickettsia. J Clin Microbiol 28:1117-1180, 1990
  221. Davidson MG, Breitschwerdt EB, WALKER DH, Levy MG, Carlson CS, Hardie EM, Grindem CA, Nasisse MP: Vascular permeability and coagulation during Rickettsia rickettsii infection in dogs. Am J Vet Res 51:165-170, 1990
  222. Smith, JH, Rotterdam, HZ, Christie JD, Lindner LE, Braunstein H, Hackman RC, Moskowitz LB, WALKER DH: Specialty Conference. Infectious and Inflammatory Diseases. Mod Pathol 3:223-233, 1990
  223. Weiss KL, WALKER DH: New and improved vaccines against rickettsial infections. Rocky Mountain spotted fever, epidemic typhus, and scrub typhus. In: New Generation Vaccines. Woodrow GC, Levine MM, eds. Marcel Dekker, Inc., New York, NY, 357-374, 1990
  224. Yu XJ, WALKER DH, Jerrells TR: Polypeptides constituting the antigenic basis for identification of Rickettsia sibirica species by the standard serotyping method for spotted fever group rickettsiae. Acta Virol 34:71-79, 1990
  225. Breitschwerdt EB, Levy MG, Davidson MG, WALKER DH, Burgdorfer W, Curtis BC, Babineau CA: Kinetics of IgM and IgG responses to experimental and naturally acquired Rickettsia rickettsii infection in dogs. Am J Vet Res 51:1312-1316, 1990
  226. Ruiz-Beltran R, Herrero-Herrero JI, WALKER DH, Cunado-Rodriguez A: Mechanism of upper gastrointestinal hemorrhage in Mediterranean spotted fever. Trop Geogr Med 42:78-82, 1990
  227. WALKER DH, Parks FM, Betz TG, Taylor JP, Muehlberger, JW: Histopathology and immunohistologic demonstration of the distribution of Rickettsia typhi in fatal murine typhus. Am J Clin Pathol 91:720-724, 1989
  228. Uchida T, Yu XJ, Uchiyama T, WALKER DH: Identification of a unique spotted fever group rickettsia from humans in Japan. J Infect Dis 159:1122-1126, 1989
  229. Nichols MM, WALKER DH, Frates RC, Davis A: Three-month-old infant with diarrhea, fever, and rash. J Pediatr 114:154-160, 1989
  230. Davidson MG, Breitschwerdt EB, WALKER DH, Nasisse MP, Sussman WE: Identification of rickettsiae in cutaneous biopsy specimens from dogs with experimental Rocky Mountain spotted fever. J Vet Intern Med 3:8-11, 1989
  231. WALKER DH: Rickettsialpox. In: Infectious Diseases. Hoeprich P, ed. JB Lippincott Co, Philadelphia, PA, 968-969, 1989
  232. WALKER DH: The rickettsia-host interaction. In: Intracellular Parasitism. Moulder JW, ed. CRC Press, Inc, Boca Raton, FL, 79-92, 1989
  233. WALKER DH: Spotted fevers. In: Infectious Diseases. Hoeprich P, ed. JB Lippincott Co, Philadelphia, PA, 967-968, 1989
  234. WALKER DH: Pathology of Q fever. In: Biology of Rickettsial Diseases, Vol II. WALKER DH, ed. CRC Press, Inc, Boca Raton, FL, 17-27, 1988
  235. WALKER DH: Role of the composition of rickettsiae in rickettsial immunity: typhus and spotted fever group. In: Biology of Rickettsial Diseases, Vol II. WALKER DH, ed. CRC Press, Inc, Boca Raton, FL, 101-109, 1988
  236. WALKER DH, Peacock MG: Laboratory diagnosis of rickettsial diseases. In: Biology of Rickettsial Diseases, Vol II. WALKER DH, ed. CRC Press, Inc, Boca Raton, FL, 135-155, 1988
  237. WALKER DH: Pathology and pathogenesis of the vasculotropic rickettsioses. In: Biology of Rickettsial Diseases, Vol. I. WALKER DH, ed. CRC Press, Inc, Boca Raton, FL, 115-138, 1988
  238. WALKER DH: The pathogenesis and pathology of the hemorrhagic state in viral and rickettsial infections. In: Handbook of Viral and Rickettsial Hemorrhagic Fevers. Gear JHS, ed. CRC Press, Inc, Boca Raton, FL, 9-45, 1988
  239. WALKER DH: Diagnosis of rickettsial diseases. In: Pathology Annual. Rosen PP, Fechner RE, ed. Appleton & Lange, Norwalk, 69-96, 1988
  240. WALKER DH, Lane TW: Rocky Mountain spotted fever: clinical signs, symptoms, and pathophysiology. In: Biology of Rickettsial Diseases, Vol I. WALKER DH, ed. CRC Press, Inc, Boca Raton, FL, 63-78, 1988
  241. WALKER DH (ed): Biology of Rickettsial Diseases. Boca Raton; CRC Press, Inc. Vols I&II, 1988
  242. Breitschwerdt EB, WALKER DH, Levy MG, Burgdorfer W, Corbett WT, Hurlbert SA, Stebbins ME, Curtis BC, Allen DA: Clinical, hematologic, and humoral immune response in female dogs inoculated with Rickettsia rickettsii and Rickettsia montana. Am J Vet Res 49:70-6, 1988
  243. Jerrells TR, Li H, WALKER DH: In vivo and in vitro role of gamma interferon in immune clearance of Rickettsia species. Adv Exp Med Biol 239:193-200, 1988
  244. Han L, Lenz B, WALKER DH: Protective monoclonal antibodies recognize heat-labile epitopes on surface proteins of spotted fever group rickettsiae. Infect Immun 56:2587-2593, 1988
  245. Shapiro HL, WALKER DH: Diagnosis of infectious diseases by immunohistology, immunocytology, and in situ hybridization. In: Immunohistology and Diagnostic Pathology. Jennette JC, ed. CRC Press, Inc, Boca Raton, FL, 257-292, 1988
  246. Horney LF, WALKER DH: Meningoencephalitis as a major manifestation of Rocky Mountain spotted fever. South Med J 81:915-8, 1988
  247. Ming-Yuan F, Yu XJ, WALKER DH: Antigenic analysis of Chinese strains of spotted fever group rickettsiae by protein immunoblotting. Am J Trop Med Hyg 39:497-501, 1988
  248. WALKER DH, Occhino C, Tringali GR, DiRosa S, Mansueto S: Pathogenesis of rickettsial eschars: the tache noire of boutonneuse fever. Hum Pathol 19:1449-1454, 1988
  249. Wang JG, WALKER DH: Identification of spotted fever group rickettsiae from human and tick sources in the People's Republic of China. J Infect Dis 156:665-669, 1987
  250. Tringali G, Mansueto S, Barba G, Occhino C, Farinella E, Vitale G, WALKER DH: Familial cases of boutonneuse fever. Eur J Epidemiol 3:414-418, 1987
  251. WALKER DH, Herrero-Herrero JI, Ruiz-Beltrán R, Bullón-Sopelana A, Ramos-Hidalgo A: The pathology of fatal Mediterranean spotted fever. Am J Clin Pathol 87:669-672, 1987
  252. Feng HM, WALKER DH, Wang JG: Analysis of T-cell-dependent and -independent antigens of Rickettsia conorii with monoclonal antibodies. Infect Immun 55:7-15, 1987
  253. Li H, Jerrells TR, Spitalny GL, WALKER DH: Gamma interferon as a crucial host defense against Rickettsia conorii in vivo. Infect Immun 55:1252-1255, 1987
  254. Winn WC, WALKER DH: Viral infections. In: Dial DH, Hammer SP, eds. Pulmonary Pathology. 2nd ed. New York (NY): Springer-Verlag. P. 429-464, 1987
  255. Wang J-G, WALKER DH, Han L, Lenz B, Jerrells, TR: Barbash strain spotted fever group rickettsia is a strain of Rickettsia conorii and differs from Rickettsia sibirica. Acta Virol 31:489-498, 1987
  256. Herrero-Herrero JI, WALKER DH, Ruiz-Beltran R: Immunohistochemical evaluation of the cellular immune response to Rickettsia conorii in taches noires. J Infect Dis 155:802-805, 1987
  257. WALKER DH, Murphy FA: Pathology and pathogenesis of arenavirus infections. In: Current Topics of Microbiology and Immunology. Oldstone MBA, ed. Springer-Verlag, New York, NY, 38-133, 1987
  258. Fan M-Y, WALKER DH, Liu Q-H, Han L, Bai H-C, Jia-Ke Z, Brenda L, Cai H: Rickettsial and serologic evidence for prevalent spotted fever rickettsiosis in Inner Mongolia. Am J Trop Med Hyg 36:615-620, 1987
  259. Fan M-Y, Wang J-G, Jiang Y-X, Zong D-G, Brenda L, WALKER DH: Isolation of a spotted fever group rickettsia from a patient and related ecologic investigations in Xinjiang Uygur Autonomous Region of China. J Clin Microbiol 25:628-632, 1987
  260. WALKER DH, Staiti A, Mansueto S, Tringali G: Frequent occurrence of hepatic lesions in boutonneuse fever. Acta Trop 43:175-181, 1986
  261. Williams JC, WALKER DH, Peacock MG, Stewart ST: Humoral immune response to Rocky Mountain spotted fever in experimentally infected guinea pigs: immunoprecipitation of lactoperoxidase 125I-labeled proteins and detection of soluble antigens of Rickettsia rickettsii. Infect Immun 52:120-127, 1986
  262. Feng HM, Kirkman C, WALKER DH: Radioimmunoprecipitation of [35S] methionine-radiolabeled proteins of Rickettsia conorii and Rickettsia rickettsii. J Infect Dis 154:717-721, 1986
  263. Tringali G, Intonazzo V, Perna AM, Mansueto S, Vitale G, WALKER DH: Epidemiology of boutonneuse fever in western Sicily: distribution and prevalence of spotted fever group rickettsial infection in dog ticks (Rhipicephalus sanguineus). Am J Epidemiol 123:721-727, 1986
  264. Jackson MD, Kirkman C, Bradford WD, WALKER DH: Rocky Mountain spotted fever: hepatic lesions in childhood cases. Pediatr Pathol 5:379-388, 1986
  265. Raoult D, Lena D, Perrimont H, Gallais H, WALKER DH, Casanova P: Haemolysis with Mediterranean spotted fever and glucose-6-phosphate dehydrogenase deficiency. Trans R Soc Trop Med Hyg 80:961-962, 1986
  266. McCormick JB, WALKER DH, King IJ, Webb PA, Elliott LH, Whitfield SG, Johnson KM: Lassa virus hepatitis: a study of fatal Lassa fever in humans. Am J Trop Med Hyg 35:401-407, 1986
  267. WALKER DH: Rickettsiae. Prepared for the ASM Committee on Educational Materials. Clin Microbiol. Health and Education Resources, Inc., Bethesda, MD, 233-238, 1985
  268. Roggli VL, Keener S, Bradford WD, WALKER DH, Pratt PC: Pulmonary pathology of Rocky Mountain spotted fever (RMSF) in children. Pediatr Pathol 4:47-57, 1985
  269. Lange JV, Mitchell SW, McCormick JB, WALKER DH, Evatt BL, Ramsey RR: Kinetic study of platelets and fibrinogen in Lassa virus-infected monkeys and early pathologic events in mopeia virus-infected monkeys. Am J Trop Med Hyg 34:999-1007, 1985
  270. WALKER DH, Gear JHS: Correlation of the distribution of Rickettsia conorii, microscopic lesions, and clinical features in South African tick bite fever. Am J Trop Med Hyg 34:361-371, 1985
  271. WALKER DH, Lesesne HR, Varma VA, Thacker WC: Rocky Mountain spotted fever mimicking acute cholecystitis. Arch Intern Med 145:2194-2196, 1985
  272. Breitschwerdt EB, Meuten DJ, WALKER DH, Levy M, Kennedy K, King M, Curtis B: Canine Rocky Mountain spotted fever: a kennel epizootic. Am J Vet Res 46:2124-2128, 1985
  273. WALKER DH, Montenegro MR, Hegarty BC, Tringali GR: Rocky Mountain spotted fever vaccine: a regional need. South Med J 77:447-449, 1984
  274. WALKER DH, Firth WT, Hegarty BC: Injury restricted to cells infected with spotted fever group rickettsiae in parabiotic chambers. Acta Trop 41:307-312, 1984
  275. Butt JD, Bouldin TW, WALKER DH: Morphologic characteristics of a unique intracytoplasmic neuronal inclusion body. Acta Neuropathol (Berl) 62:345-347, 1984
  276. WALKER DH: Rocky Mountain spotted fever. In: Conn’s Current Therapy. Rakel RE, ed. WB Saunders Co, Philadelphia, PA, 57-58, 1984
  277. WALKER DH, Lange JV, Hanff PA, Tidwell RR, Hegarty BC: Antigens of Rickettsia rickettsii and Rickettsia conorii. In: Microbiology 1984. Lieve L, Schlessinger D, eds. Am Soc Microbiology, Washington, D.C., 244-247, 1984
  278. Lange JV, WALKER DH: Production and characterization of monoclonal antibodies to Rickettsia rickettsii. Infect Immun 46:289-294, 1984
  279. Montenegro NR, WALKER DH, Hegarty BC: Infection of genetically immunodeficient mice with Rickettsia conorii. Acta Virol 23:508-514, 1984
  280. WALKER DH, Tidwell RR, Rector TM, Geratz JD: Effect of synthetic protease inhibitors of the amidine type on cell injury by Rickettsia rickettsii. Antimicrob Agents Chemother 25:582-585, 1984
  281. Randall MB, WALKER DH: Rocky Mountain spotted fever: Gastrointestinal and pancreatic lesions and rickettsial infection. Arch Pathol Lab Med 108:963-967, 1984
  282. Mansueto S, Tringali G, DiLeo R, Maniscalco M, Montenegro MR, WALKER DH: Demonstration of spotted fever group rickettsiae in the tache noire of a healthy person in Sicily. Am J Trop Med Hyg 33:479-482, 1984
  283. WALKER DH, Okiye G: Chronic granulomatous disease involving the central nervous system. Pediatr Pathol 1:159-167, 1983
  284. Folds JD, WALKER DH, Hegarty BC, Banasiak D, Lange JV: Rocky Mountain spotted fever vaccine in an animal model. J Clin Microbiol 18:321-326, 1983
  285. WALKER DH, Hawkins HK, Hudson P: Fulminant Rocky Mountain spotted fever. Its pathologic characteristics associated with glucose-6-phosphate dehydrogenase deficiency. Arch Pathol Lab Med 107:121-125, 1983
  286. WALKER DH, Firth WT, Ballard JG, Hegarty BC: Role of the phospholipase-associated penetration mechanism in cell injury by Rickettsia rickettsii. Infect Immun 40:840-842, 1983
  287. Tracy SL, McGinnis MR, Peacock JE Jr., Cohen MS, WALKER DH: Disseminated infection by Aspergillus terreus. Am J Clin Pathol 80:728-733, 1983
  288. Cohen MS, Jaques PF, Wall SD, WALKER DH: A fatal eosinophilic process in a Laotian refugee. Am J Clin Pathol 80:738-743, 1983
  289. Kaplowitz LG, Lange JV, Fischer JJ, WALKER DH: Correlation of rickettsial titers, circulating endotoxin, and clinical features in Rocky Mountain spotted fever. Arch Intern Med 143:1149-1151, 1983
  290. Montenegro MR, Mansueto S, Hegarty BC, WALKER DH: The histology of "taches noires" of boutonneuse fever and demonstration of Rickettsia conorii in them by immunofluorescence. Virchows Arch 400:309-317, 1983
  291. WALKER DH, McCormick FB, Johnson KM, Webb PA, Komba-Kono G, Elliott LH, Gardner JJ: Pathologic and virologic study of fatal Lassa fever in man. Am J Pathol 107:349-356, 1982
  292. Ishak KG, WALKER DH, Coetzer JAW, Gardner JJ, Gorelkin L: Viral hemorrhagic fevers with hepatic involvement: pathologic aspects with clinical correlations. In: Progress in Liver Disease. Popper H, Schaffner F, eds. Grune and Stratton, New York, NY, 29:495-515, 1982
  293. WALKER DH: Rickettsial diseases: an update. In: Current Topics in Inflammation and Infection. Majno G, Cotran R, eds. Williams and Wilkins Co, Baltimore, MD, 188-204, 1982
  294. Lange JV, WALKER DH, Wester TB: Documented Rocky Mountain spotted fever in wintertime. JAMA 247:2403-2404, 1982
  295. WALKER DH, McGinnis MR: Opportunistic fungal infection. Symposium on Respiratory Infections. In: Clinics in Laboratory Medicine. Winn WC Jr, ed. WB Saunders Co, Philadelphia, PA, 2:407-413, 1982
  296. WALKER DH, Johnson KM, Lange JV, Gardner JJ, Kiley MP, McCormick JB: Experimental infection of rhesus monkeys with Lassa virus and a closely related arenavirus, Mozambique virus. J Infect Dis 146:360-368, 1982
  297. Smith GW, WALKER DH: Disseminated infection with Aspergillus flavus in an alcoholic patient. South Med J 75:1148-1150, 1982
  298. McGinnis MR, WALKER DH, Dominy IE, Kaplan W: Zygomycosis caused by Cunninghamella bertholletiae: Clinical and pathological aspects. Arch Pathol Lab Med 106:282-286. 1982
  299. WALKER DH, Firth WT, Edgell C-JS: Human endothelial cell culture plaques induced by Rickettsia rickettsii. Infect Immun 37:301-306, 1982
  300. Stephens DS, WALKER DH, Schaffner W, Kaplowitz LG, Brashear HR, Roberts R, Spickard WA Jr: Pseudodiphtheria: prominent pharyngeal membrane associated with fatal paraquat ingestion. Ann Intern Med 94:202-204, 1981
  301. Bowdre JH, Campbell JL, WALKER DH, Tart DE: American mucocutaneous leishmaniasis: culture of a leishmania species from peripheral blood leukocytes. Am J Clin Pathol 75:435-438, 1981
  302. Wheeler MS, McGinnis MR, Schell WA, WALKER DH: Fusarium infection in burned patients. Am J Clin Pathol 75:304-311, 1981
  303. Adams JS, WALKER DH: The liver in Rocky Mountain spotted fever. Am J Clin Pathol 75:156-161, 1981
  304. WALKER DH, Kirkman HN, Wittenberg PH: Genetic states possibly associated with enhanced severity of Rocky Mountain spotted fever. In: Rickettsiae and Rickettsial Diseases. Burgdorfer W, Anacker RL, eds. Academic Press, New York, NY, 621-630, 1981
  305. WALKER DH, Bradford WD: Rocky Mountain spotted fever in childhood. In: Perspectives in Pediatric Pathology. Infectious Diseases. Rosenberg HS, Bernstein J, eds. Masson Publishing USA, Inc, New York, NY, 6:35-61, 1981
  306. WALKER DH, Gay RM, Valdes-Dapena M: The occurrence of eschars in Rocky Mountain spotted fever. J Am Acad Dermatol 4:571-576, 1981
  307. WALKER DH, Cain BG, Lange JV, Harrison A: Pathologic and rickettsial events in tetracycline-treated experimental Rocky Mountain spotted fever. In: Rickettsiae and Rickettsial Diseases. Burgdorfer W, Anacker RL, eds. Academic Press, New York, NY, 347-362, 1981
  308. Powell DA, WALKER DH: Nontuberculous mycobacterial endobronchitis in children. J Pediatr 96:268-270, 1980
  309. WALKER DH, Crawford CG, Cain BG: Rickettsial infection of the pulmonary microcirculation: the basis for interstitial pneumonitis in Rocky Mountain spotted fever. Hum Pathol 11:263-272, 1980
  310. McGinnis MR, WALKER DH, Folds JD: Hansenula polymorpha infection in a child with chronic granulomatous disease. Arch Pathol Lab Med 104:290-292, 1980
  311. WALKER DH, Cain BG: The rickettsial plaque. Evidence for direct cytopathic effect of Rickettsia rickettsii. Lab Invest 43:388-396, 1980
  312. WALKER DH, Paletta CE, Cain BG: Pathogenesis of myocarditis in Rocky Mountain spotted fever. Arch Pathol Lab Med 104:171-174, 1980
  313. WALKER DH, Kirkman HN: Rocky Mountain spotted fever and deficiency in glucose-6-phosphate dehydrogenase. J Infect Dis 142:771, 1980
  314. WALKER DH, Burday MS, Folds JD: Laboratory diagnosis of Rocky Mountain spotted fever. South Med J 73:1443-1447, 1980
  315. Sanders KL, WALKER DH, Lee TJ: Relapse of Legionnaires' disease in a renal transplant recipient. Arch Int Med 140:833-834, 1980
  316. Donohue JF, Scott RJ, WALKER DH, Bromberg PA: Phycomycosis: A cause of bronchial obstruction. South Med J 73:734-736, 1980
  317. WALKER DH, Akov Y, Cain BG: Ultrastructural and virological aspects of Langat virus-induced SSPE in suckling hamsters. Br J Exp Pathol 60:604-612, 1979
  318. Krauss JS, WALKER DH: Miliary tuberculosis and consumption of clotting factors by multifocal vasculopathic coagulation. South Med J 72:1479-1481, 1979
  319. WALKER DH, Mattern WD: Acute renal failure in Rocky Mountain spotted fever. Arch Intern Med 139:443-448, 1979
  320. Fischer JJ, WALKER DH: Invasive pulmonary aspergillosis associated with influenza. JAMA 241:1493-1494, 1979
  321. WALKER DH, Henderson FW: Effect of immunosuppression on Rickettsia rickettsii infection in guinea pigs. Infect Immun 20:221-227, 1978
  322. Green WR, WALKER DH, Cain BG: Fatal viscerotropic Rocky Mountain spotted fever: report of a case diagnosed by immunofluorescence. Am J Med 64:523-528, 1978
  323. WALKER DH, Adamec T, Krigman M: Disseminated petriellidosis (allescheriosis). Arch Pathol Lab Med 102:158-160, 1978
  324. WALKER DH, Cain BG: A method for specific diagnosis of Rocky Mountain spotted fever on fixed, paraffin-embedded tissue by immunofluorescence. J Infect Dis 137:206-209, 1978
  325. Murphy FA, WALKER DH: Arenaviruses: persistent infection and viral survival in reservoir hosts. In: Viruses and Environment. Kurstak E, Maramorosch K, eds. Academic Press, New York, NY, 155-180, 1978
  326. WALKER DH, Cain BG, Olmstead PM: Laboratory diagnosis of Rocky Mountain spotted fever by immunofluorescent demonstration of Rickettsia rickettsii in cutaneous lesions. Am J Clin Pathol 69:619-623, 1978
  327. WALKER DH, Cain BG, Olmstead PM: Specific diagnosis of Rocky Mountain spotted fever by immunofluorescent demonstration of Rickettsia rickettsii in biopsy of skin. The Public Health Laboratory 36:96-100, 1978
  328. Camenga DL, WALKER DH, Murphy FA: Anticonvulsant prolongation of survival in adult murine lymphocytic choriomeningitis. I. Drug treatment and virologic studies. J Neuropath Exp Neurol 36:9-20, 1977
  329. WALKER DH, Camenga DL, Whitfield S, Murphy FA: Anticonvulsant prolongation of survival in adult murine lymphocytic choriomeningitis. II. Ultrastructural observations of pathogenetic events. J Neuropath Exp Neurol 36:21-40, 1977
  330. WALKER DH, Harrison A, Henderson F, Murphy FA: Identification of Rickettsia rickettsii in a guinea pig model by immunofluorescent and electron microscopic techniques. Am J Pathol 86:343-358, 1977
  331. Edgcomb JH, WALKER DH, Johnson CM: Klossiella in the opossum. Vet Pathol 13:315-318, 1976
  332. Murphy FA, Winn WC Jr, WALKER DH, Flemister MR, Whitfield SG: Early lymphoreticular viral tropism and antigen persistence. Tamiami virus infection in the cotton rat. Lab Invest 34:125-140, 1976
  333. WALKER DH, Harrison A, Murphy K, Flemister M, Murphy FA: Lymphoreticular and myeloid pathogenesis of Venezuelan equine encephalitis in hamsters. Am J Pathol 84:351-370, 1976
  334. WALKER DH, Wulff H, Murphy FA: Experimental Lassa virus infection in the squirrel monkey. Am J Pathol 80:261-272, 1975
  335. WALKER DH, Murphy FA, Whitfield SG, Bauer SP: Lymphocytic choriomeningitis: Ultrastructural pathology. Exp Mol Pathol 23:245-265, 1975
  336. Winn WC Jr, WALKER DH: The pathology of human Lassa fever. Bull WHO 52:535-545, 1975
  337. WALKER DH, Wulff H, Lange JV, Murphy FA: Comparative pathology of Lassa virus infection in monkeys, guinea pigs, and Mastomys natalensis. Bull WHO 52:523-535, 1975
  338. Edgcomb JH, WALKER DH, Johnson CM: Pathological features of Trypanosoma cruzi infections of Rattus rattus. Arch Pathol 96:36-38, 1973
  339. WALKER DH, Gill TJ III, Corson JM: Leiomyosarcoma in a renal allograft recipient treated with immunosuppressive drugs. JAMA 215:2084-2086, 1971
  340. Knight SC, WALKER DH, Ling NR: Factors affecting the activation of rabbit peripheral, spleen, thymus and bone marrow cells by homologous lymphoid cells and heterologous erythrocytes. Cytobios 3:65-76, 1971

Search PubMed database for David Walker