Srinivasan Rajaraman

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Srinivasan Rajaraman
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Academic Appointments
Appointment Organization
Professor Pathology
Honors
Title Organization Year(s)
Course Co-Director, Renal/Fluids/Electrolytes Course, Integrated Medical Curriculum, UTMB. The Best Course for 2001, awarded by the Sophomore Class 2001
Men of Achievement 1994
International Directory of Distinguished Leadership 1994
Invited participant in the Tokten Project, under the auspices of the United Nations 1993
Who's Who in Science and Engineering 1991
West's Who's Who in Health and Medical Services 1990
American Men and Women of Science 1989
Sainya Seva Medal with Himalayan Clasp for Service in High Altitude Area in the Indian Armed Forces 1967
First prize in Natural Sciences (Biology) in Pre-University Course, St. Joseph's College, Trichy, India 1959
Selected Publications
  1. Slogoff,M., Ethridge, R., Rajaraman, S., and Evers, MB. COX-2 inhibition results in alterations in Nuclear Factor(NF)-kappa B activation but not cytokine production in acute pancreatitis. J Gastrointest Surg. 8: 511-519, 2004
  2. Hashimoto, K., Ethridge, R., Saito, H., Rajaraman, S., and Evers, BM. The PPAR gamma Ligand, 15d-PGJ2, attenuates the severity of Cerulein-induced acute Pancreatitis. Pancreas. 27: 58-66, 2003
  3. Thomas, R., Rajaraman, S., and Evers, BM. Effect of ileocolonic transposition on gut morphology, gene expression, and function. J Surg Res. 109 : 31-36, 2003
  4. Zakir, A., Woodside, K., Feliberti, E., Rajaraman, S., Gugliuzza, K., and Daller, J. Late renal allograft rupture in a patient with small vessel vasculitis following discontinuation of immunosuppression. Transpl Int. 16:761-764, 2003
  5. Arany, I., Chen S., Megyesi, J., Adler-Storthz, K., Chen, Z., Rajaraman, S., Ember, I., Tyring, S., and Brysk, M. Diferentiation-dependent expression of signal transducers and activators of transcription (STATs) might modify responses to growth factors in the cancers of the head and neck. Cancer Lett. 199: 83-89, 2003
  6. Sairam, V., Kalia, A., Rajaraman, S., and Travis, L. Secondary resistance to cyclosporin A in children with nephrotic syndrome. Pediatr Nephrol. 17:842-846, 2002
  7. Ethridge, R., Chung, D., Ehlers, R., Rajaraman, S., and Evers, BM. Selective inhibition of NF-kappaB attenuates the severity of caerulein-induced acute pancreatitis. J Am Coll Surg. 195: 497-505, 2002
  8. Ethridge, R.,Chung, D., Slogoff, M., Ehlers, R., Hellmich, M., Rajaraman, S., Saito, H., Uchida, T., and Evers, M. Cyclooxygenase-2 gene disruption attenuates the severity of acute pancreatitis and pancreatitis-associated lung injury. Gastroenterology. 123: 1311-1322, 2002
  9. Bello-Reuss, E., Holubec, K., and Rajaraman, S. Angiogenesis in autosomal-dominant polycystic kidney disease. Kidney Int. 60: 37-45, 2001.
  10. Ahuja, T., Boughton, J., Weiss, J., Memon, A., Remmers, A., and Rajaraman, S. Late recurrence of lupus nephritis in a renal transplant recipient: Response to mycophenolate mofetil. Am J Med Sci. 322: 166-169, 2001
  11. Ethridge, R., Hashimoto, K., Rajaraman, S., Chung, D., and Evers, B. Selective inhibition of NF-kappa B results in attenuation of acute pancreatitis and pancreatitis-associated lung injury. Surg Forum LII: 25-27, 2001
  12. Chen, S-H., Arany, I., Apisarnthanarax, N., Rajaraman, S., Tyring, S., Horikoshi, T., Brysk, H., and Brysk, M. Response of keratinocytes from normal and psoriatic epidermis to interferon-gamma differs in the expression of zinc-alpha 2-glycoprotein and cathepsin D. FASEB J. 14: 565-571, 2000
  13. Wang, L., Molina, C., and Rajaraman, S. Intestinal infarction due to vascular catastrophy in an HIV-infected patient. AIDS Reader. 10: 718-721, 2000
  14. Agraharkar, M., Gokhale, S., Le, L., Rajaraman, S., and Campbell, G. Cardiopulmonary manifestations of Henoch-Schonlein purpura. Am J Kidney Dis. 35: 319-322, 2000
  15. Jeschke, M., Debroy, M., Wolf, S., Rajaraman, S., and Thompson, J. Burn and starvation increase programmed cell death in small bowel epithelial cells. Dig Dis Sci. 45: 415-420, 2000
  16. Ethridge, R., Ehlers, R., Hellmich, M., Rajaraman, S., and Evers, B. Acute pancreatitis results in induction of heat shock proteins 70 and 27 and heat shock factor-1. Pancreas. 21: 248-256, 2000
  17. Haas, M., Rajaraman, S., Ahuja, T., Kittaka, M., and Cavallo, T. Fibrillary/Immunotactoid glomerulonephritis in HIV-positive patients: a report of three cases. Nephrol Dial Transplant. 15: 1679-1683, 2000
  18. Agraharakar, M., Fahlen, M., Siddiqui, M., and Rajaraman, S. Waterhouse-Friderichsen syndrome and bilateral renal cortical necrosis in meningococcal sepsis. Am J Kidney Dis. 36: 396-400, 2000
  19. Shahinian, V., Rajaraman, S., Borucki, M., Grady, J., Hollander, W., and Ahuja, T. Prevalence of HIV-Associated nephropathy in autopsies of HIV-Infected patients. Am J Kidney Dis. 35: 884-888, 2000
  20. Wolf, SE., Debroy, MA., Ikeda, H., Jeschke, M., Matin, S., Rajaraman, S., Ko, TC., Englander, E., Norman, JG., and Thompson, J. Increased small bowel epithelial turnover in interleukin-1 receptor-knockout mice. Ann Surg. 232: 42-45, 2000
  21. Yu, D., Seitz, P., Selvanayagam, P., Rajaraman, S., Townsend, C., and Cooper, C. 1992 Effects of Parathyroid Hormone-Related Peptide on Adenosine 3',5'-Monophosphate and Ornithine Decarboxylase in a human colonic cell line. Endocrinology. 130:1993-2000
  22. Lee, HM., Udupi, V., Englander, E., Rajaraman, S., coffey, R., and Greeley, G. Stimulatory actions of insulin-like growth factor-I and transforming growth factor-alpha on intestinal neurotensin and peptide YY. Endocrinology. 140: 4065-4069, 1999
  23. Ahuja, T., Borucki, M., Funtanilla, M., Shahinian, V., Hollander,M.,and Rajaraman,S. Is the prevalence of HIV-Associated Nephropathy Decreasing? Am J Nephrol. 19: 655-659, 1999
  24. Wolf, D., Aronson, J., Rajaraman, S., and Veasey, S. Wischnewski ulcers and acute pancreatitis in two hospitalized patients with cirrhosis,portal vein thrombosis and hypothermia. J Forensic Sci. 44: 1082-1085, 1999
  25. Wolf, S., Ikeda, H., Matin, S., Debroy, M., Rajaraman, S., Herndon, D., and Thompson, J. Cutaneous burn increases apoptosis in the gut epithelium of mice. J Am Coll Surg. 188: 10-16, 1999
  26. Ahuja, T., Velasco, A., Deiss, W., Indrikovs, A., and Rajaraman, S. Diabetic nephropathy with anti-GBM nephritis. Am J Kidney Dis. 31:127-130, 1998
  27. Selvanayagam, P., Lei, G., Bell, T.,Ram, S., Brysk, H., Rajaraman, S., and Brysk, M. Desquamin is an epidermal ribonuclease. J Cell Biochem. 68:74-82, 1998
  28. Ahuja, T., Remmers, A., and Rajaraman, S. Acute renal failure in a patient with AIDS: Histoplasmosis-Induced Granulomatous Interstitial Nephritis. Am J Kidney Dis. 32:E3, 1998
  29. Horikoshi, T., Arany, I., Rajaraman, S., Chen, S., Brysk, H., Lei, G., Tyring, S., and Brysk, M. Isoforms of cathepsin D and human epidermal differentiation. Biochimie. 80: 605-612, 1998
  30. Papaconstantinou, H., Hwang, K., Rajaraman, S., Hellmich, M., Townsend, C., and Ko, T. Glutamine deprivation induces apoptosis in intestinal epithelial cells. Surgery. 124: 152-159, 1998
  31. Gill, K., Yannariellobrown, J., Patel, J., Nakajima, N., Rajaraman, S., and Trocme, S. ICAM-1 expression in corneal epithelium of a patient with vernal keratoconjunctivitis. Cornea. 16: 107-111, 1997
  32. Ernest, S., Rajaraman, S., Megyesi, J., and BelloReuss, E. Expression of MDR1(multidrug resistance) gene and its protein in normal human kidney. Nephron.77:284-289, 1997
  33. Lei, G., Arany, I., Selvanayagam, P., Rajaraman, S.,Ram, S., Brysk, H., Tyring, S., and Brysk, M. Detection and cloning of epidermal zinc-alpha 2-glycoprotein cDNA and expression in normal human skin and in tumors. J Cell Biochem 67:216-222, 1997
  34. Awasthi, S., Singhal, S., Srivastava, S., Chaubey, M., Piper, J., Yallampalli, C., Rajaraman, S., and Awasthi, Y. Rat GST 8-8 is expressed predominantly in myeloid origin cells infiltrating the gravid uterus. Int. J. Biochem. Cell Biol. 29: 807-813, 1997
  35. Brysk, M., Lei, G., Rajaraman, S., Selvanayagam, P., Rassekh, C., Brysk, H., Tyring, S., and Arany, I. Gene expression of Zinc-alpha2-Glycoprotein in normal human epidermal and buccal epithelia. in vivo. 11:271-274, 1997
  36. Matin, S., Ikeda, H., Guo, Y., Wolf, S., Ko, T., Rajaraman, S., Herndon, D., and Thompson, J. Burn-Induced stimulation of Apoptosis-Related genes in rat small bowel. Surg Forum. XLVIII:221-223, 1997
  37. Vaidya, S., Wang, C., Roorda, C., Billings, A., Rajaraman, S., and Fish, J. Tolerance for graft-versus-host disease by intrathymic injection of recipient-type splenocytes into donor. Transplant Proc. 29: 1073-1075, 1997
  38. Bhat, H., Springer, I., Rajaraman, S., and Liehr, J. Immunocytochemical localization of C-myc and C-jun oncoproteins in hamster kidney and estrogen-induced kidney tumors. J. Steroid Biochem. Molec. Biol. 60: 99-104, 1997
  39. Li, H., Seitz, P., Selvanayagam, P., Rajaraman, S., and Cooper, C. Effect of endogenously produced Parathyroid Hormone-Related Peptide on growth of a human hepatoma cell line (Hep G2). Endocrinology. 137:2367-2374, 1996
  40. Rajaraman, S. Coagulation mechanisms (Glomerulonephrits). In Rudolph, AM, Hoffman, JIE, Rudolph, CD, eds, Rudolph's Pediatrics. 20th ed. Stamford, CT, Appleton & Lange, 1996, 1352
  41. Vaidya, S., Rajaraman, S., Orchard, P., and Fish, J. Frequency, immunoglobulin subtype and clinical significance of antiphospholipid antibodies in ESRD patients. In Terasaki, P.(ed.) Visuals of the 11th Clinical Histocompatibility Workshop. One Lambda: Los Angeles,CA, 1996
  42. Memar, O., Rajaraman, S., Thotakura, R., Tyring, S., Fan, J-L., Seetharamaiah, G., Lopez, A., Jordon, R., and Prabhakar, B. Recombinant Desmoglein 3 has the necessary epitopes to adsorb and induce Blister-Causing antibodies. J Invest Dermatol. 106:261-268, 1996
  43. Evers, B., Zhou, Z., Dohlen, V., Rajaraman, S., Thompson, J., and Townsend, C. Fetal and Neoplastic expression of the neurotensin gene in the human colon. Ann Surg. 223:464-470, 1996.124
  44. Vaidya, S., Wang, C., Roorda, C., Billings, A., Rajaraman, S., and Fish, J. Prevention of graft-versus-host disease by intrathymic injection of recipient-type splenocytes into donor. Transplantation. 62: 1366-1368, 1996
  45. Li, H., Seitz, P., Selvanayagam, P., Rajaraman, S., and Cooper, C. Alteration of secretion of Parathyroid Hormone-Related Peptide and expression of its mRNA in a human hepatoma cell line (HEP G2) treated with agents that affect cell growth. Endocrine. 5: 323-330, 1996
  46. Arany, I., Tyring, S., Hoskins, S., Brysk, H., Chen, S., Selvanayagam, P., Rajaraman, S., and Brysk, M. Response of cultured cells from the epidermis and the buccal mucosa to TGF-beta 1 and comparison to interferon-gamma. In Vivo. 10: 405-409, 1996
  47. Ahmed, A., Nouraldeen, A., AbdelRahman, S., and Rajaraman, S. Role of glutathione modulation in acrylonitrile induced gastric DNA damage in rats. Arch.Toxicol. 70: 620-627, 1996
  48. Singh, P., Owlia, A., Varro, A., Dai, B., Rajaraman, S., and Wood, T. Gastrin gene expression is required for the proliferation and tumorigenicity of human colon cancer cells. Cancer Res. 56:4111-4115, 1996
  49. Gomez, G., Udupi, V., Qi, X., Lluis, F., Rajaraman, S., Thompson, J., and Greeley, G. Growth hormone upregulates gastrin and peptide YY gene expression. Am. J. Physiol. 271:E582-E586, 1996
  50. Memar, O., Christensen, B., Rajaraman, S., Goldblum, R., Tyring, S., Brysk, M., McCormick, D., El Zaim, H., Fan, J-L., and Prabhakar, B. Induction of Blister-causing antibodies by a recombinant full-length, but not the extracellula, domain of the Pemphigus Vulgaris antigen (Desmoglein 3). J.Immunol. 157: 3171-3177, 1996
  51. Rajaraman, S. Immunologic mechanisms (Glomerulonephritis). In Rudolf, AM, Hoffman, JIE, Rudolph, CD, eds. Rudolph's Pediatrics. 20th ed. Stamford, CT, Appleton & Lange, 1996, 1351-52
  52. Selvanayagam, P., and Rajaraman, S. Detection of mitochondrial genome depletion by a novel cDNA in Renal Cell Carcinoma. Lab Invest. 74:592-599, 1996
  53. Rajaraman,S. General Anatomy of the kidney. In Rudolph, AM, Hoffman, JIE, Rudolph CD,eds. Rudolph's Pediatrics. 20th ed. Stamford,CT, Appleton & Lange, 1996, 1308-1309
  54. Zhang, T., Townsend Jr., CM., Udupi, V., Yanaihara, N., Rajaraman, S., Beauchamp, RD., Ishizuk, J., Evers, BM., Gomez, G., Thompson, JC., and Greeley Jr., G. 1995. Phorbol Ester-Induced Alteration in the Pattern of Secretion and Storage of Chromogranin A and Neurotensin in a Human Pancreatic Carcinoid Cell Line. Endocrinology. 136:2252-2261
  55. Gomez, G., Zhang, T., Rajaraman, S., Thakore, K., Yanaihara, N., Townsend Jr, C., Thompson, J., and Greeley, G. 1995. Intestinal peptide YY: ontogeny of gene expression in rat bowel and trophic actions on rat and mouse bowel. Am J Physiol. 268:G71-G81
  56. Tsuchiya, T., Ishizuka, J., Sato, K., Shimoda, I., Rajaraman, S., Uchida, T., Townsend Jr., CM., and Thompson, JC. 1995. Effect of Ileo-Jejunal Transposition on the Growth of the GI Tract and Pancreas in Young and Aged Rats. J Gerontol: Med Sciences. 50A:M155-M161
  57. Li, H., Seitz, P., Thomas, M., Selvanayagam, P., Rajaraman, S., and Cooper, C. Widespread expression of the Parathyroid Hormone-Related Peptide and PTH/PTHrP receptor genes in intestinal epithelial cells. Lab Invest. 73:864-870, 1995
  58. Brysk, M., Selvanayagam, P., Arany, I., Brysk, H., Tyring, S., and Rajaraman,S.Induction of Apoptotic nuclei by Interferon-gamma and by Predesquamin in cultured keratinocytes. J Interferon and Cytokine Res. 15:1029-1035, 1995
  59. Bold, R., Ishizuka, J., Rajaraman, S., Perez-Polo, J., Townsend Jr., C., and Thompson, J. Nerve growth factor as a mitogen for a pancreatic carcinoid cell line. J Neurochem. 64:2622-2628, 1995
  60. Bhat, H., Springer, I., Rajaraman, S., and Liehr, J. Differential expression of neu mRNA and protein in hamster kidney and estrogen-induced kidney tumors. Int J Oncology. 7:535-538, 1995
  61. Sato, K., Ishizuka, J., Cooper, C., Chung, D., Tsuchiya, T., Uchida, T., Rajaraman, S., Townsend Jr, C., and Thompson, J. 1994. Inhibitory effect of calcium channel blockers on growth of Pancreatic cancer cells. Pancreas. 9:193-202
  62. Brysk, M., Bell, T., Brysk, H., Selvanayagam, P., and Rajaraman, S. 1994. Enzymatic activity of desquamin. Exp Cell Res. 214: 22-26
  63. Srivastava, R., Kalia, A., Travis, L., Diven, S., Gugliuzza, C., and Rajaraman, S. 1994. Prompt remission of post-renal transplant nephrotic syndrome with high-dose cyclosporine. Pedi Nephrol. 8:94-95
  64. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1994. Prognostic indicators in children with IgA nephropathy. Ped.Nephrol. 8:15-20
  65. Yen, A., Bell, T., Brysk, H., Rajaraman, S., and Brysk, M. 1994. Predesquamin extends maturation of cultured keratinocytes. Exp Cell Res. 213:305-307
  66. Parekh, D., Ishizuka, J., Townsend, C., Haber, B., Beauchamp, D., Karp, G., Kim, S., Rajaraman, S., Greeley, G., and Thompson, J. 1994. Characterization of a human pancreatic carcinoid in vitro: Morphology, Amine and Peptide Storage and Secretion. Pancreas. 9:83-90
  67. Brysk, M., Bell, T., Tyring, S., and Rajaraman, S. 1994. Cytokines modulate terminal differentiation and the expression of Predesquamin in cultured Keratinocytes. Exp Cell Res. 211:49-52
  68. Evers, B.M., Masaaki, I., Rajaraman, S., Parekh, D., Thakore, K., Yoshinaga, K., Uchida, T. Townsend Jr, C., and Thompson, J. 1994. Effect of aging on neurotensin-stimulated growth of rat small intestine. Am J Physiol. 267:G180-G186
  69. Wagle, N., Dallas, J., Seetharamaiah, G., Fan, J-L., Desai, R., Memar, O., Rajaraman, S., and Prabhakar, B. 1994. Induction of Hyperthyroxinemia in BALB/C but not in several other strains of mice. Autoimmunity. 18:103-112
  70. Chu, K., Higashide, S., Evers, B.M., Rajaraman, S., Ishizuka, J, Townsend Jr, C., and Thompson, J. 1994. Bombesin improves survival from methotrexate-induced enterocolitis. Ann Surg. 220:570-577
  71. Singh, P., Xu, Z., Dai, B., Rajaraman, S., Rubin, N., and Dhruva, B. 1994. Incomplete processing of progastrin expressed by human colon cancer cells - Role of non-carboxyamidated gastrins. Am J Physiol. 266:G459-G468
  72. Shimoda, I., Evers, B., Sato, K., Ishizuka, J., Rajaraman, S., Chung, D., Uchida, T., Tsuchiya, T., Greeley Jr, G., Townsend Jr, C., and Thompson, J. 1994. Age dependent increase of neurotensin expression in the ileum. Am J Physiol. 266:G706-G712
  73. Baron, P., Gugliuzza, K., Rajaraman, S., and Thompson, J. 1994. Ceruloplasmin and Deferoxamine prevent Ischemia-Reperfusion damage in kidney transplantation. Ann NY Acad Sci (Cellular, Biochemical, and Molecular Aspects of Reperfusion Injury). 723:401-402
  74. Evers, M., Rajaraman, S., Chung, D., Townsend, C., Wang, X., Graves, K., and Thompson, J. 1993. Developmental expression of the Neurotensin Gene in the rat liver. Ann Surg. 218:183-188
  75. Yallampalli, C., Rajaraman, S., and Nagamani, M. 1993. Insulin-like growth factor binding proteins in the rat uterus and their regulation by oestradiol and growth hormone. J Reprod Fertil. 97:501-505
  76. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1993. Renal Disease in Adolescents with Type I Diabetes Mellitus. Am J Kidney Dis. 22:783-790
  77. Brysk, M., Santschi, C., Bell, T., and Rajaraman, S. 1993. Predesquamin inhibits desquamation. Exp Cell Res. 209:301-306
  78. Parekh, D., Ishizuka, J., Townsend, C., Rajaraman, S., and Thompson, J.C. 1993. The effect of endogenous cholecystokinin released by Bombesin and Trypsin inhibitor on the regeneration of pancreas. Ann Surg. 218:735-741
  79. Evers, M., Rajaraman, S., Chung, D., Townsend, C., Wang, X., Graves, K., and Thompson, J. 1993. Differential expression of the neurotensin gene in the developing rat and human gastrointestinal tract. Am J Physiol. 28:482-490
  80. Seitz, P., Cooper, K., Ives, K., Ishizuka, J., Townsend, C., Rajaraman, S., and Cooper, C. 1993. Parathyroid Hormone-Related Peptide Production and Action in a Myoepithelial Cell Line Derived from Normal Human Breast. Endocrinology. 133:1116-1124
  81. Ansari, N. and Rajaraman, S. 1992. Allopurinol-Induced Nephrotoxicity: Protection by the antioxidant, butylated hydroxytoluene. Res Commun Chem Pathol Pharmacol. 75:221-229
  82. Evers, M., Ishizuka, J., Townsend, C., Rajaraman, S., and Thompson, J. 1992. Expression of Neurotensin messenger RNA in a human carcinoid tumor. 1992 Yearbook of Surgery. 352-354
  83. Juneja, H., Schmalsteig, F., Rajaraman, S., Hanson, E., Lee, S., and Brasher, W. 1992. Heterotypic adherence between murine Leukemia/Lymphoma cells and marrow stromal cells involves a recognition mechanism with Galactosyl and Mannosyl specificities. Exp Hematol. 20:405-411
  84. Brysk, M., Santschi, C., Bell, T., Wagner, R., Tyring, S., and Rajaraman, S. 1992. Culture of Basal cell carcinoma. J Invest Dermatol. 98:45-49
  85. Brysk, M., and Rajaraman, S. 1992. Cohesion and Desquamation of Epidermal Stratum corneum. (Invited Review). Progr Histochem Cytochem. 25:1-54
  86. Chung, D., Evers, M., Beauchamp, D., Upp, J., Rajaraman, S., Townsend, C., and Thompson, J. 1992. Bombesin stimulates growth of human gastrinoma. Surgery. 112:1059-1065
  87. Evers, M., Rady, P., Tyring, S., Sanchez, R., Rajaraman, S. Townsend, C., and Thompson, J. 1992. Amplification of the HER-2/neu Protooncogene in Human Endocrine Tumors. Surgery. 112:211-218
  88. Chung, D., Evers, M., Shimoda, I., Townsend Jr, C., Rajaraman, S. and Thompson, J. 1992. Effect of Neurotensin on Gut Mucosal Growth in Rats with Jejunal and Ileal Thiry-Vella Fistulas. Gastroenterology. 103:1254-1259
  89. Juneja, H., Rajaraman, S., Gay, R., Gay, S., and Schmalsteig, F. 1992. Characterization of heterotypic adherence between transformed human lymphoblastic cells and marrow stromal cells - VCAM-1 is a ligand for one of the Leukemia Cell Adhesion Proteins. Exp Hematol. 20:1263-1270
  90. Evers, M., Ishizuka, J., Townsend, C., Rajaraman, S., and Thompson, J. 1992. Expression of Neurotensin Messenger RNA in a Human Pancreatic Carcinoid Tumor. Ann NY Acad Sci. (The Neurobiology of Neurotensin). 668:342-344
  91. Yu, D., Seitz, P., Selvanayagam, P., Rajaraman, S., Townsend, C., and Cooper, C. 1992. Effects of Vasoactive Intestinal Peptide on Adenosine 3',5'-Monophosphate, Ornithine Decarboxylase, and cell growth in a Human colon cell line. Endocrinology. 131:1188-1194
  92. Sumi, S., Beauchamp, R., Townsend, C., Murakami, M., Rajaraman, S., Ishizuka, J., and Thompson, J. 1992. Inhibition of Pancreatic Adenocarcinoma cell growth by Lovastatin. Gastroenterology. 103:982-989
  93. Parekh, D., Townsend, C., Rajaraman, S., Ishizuka, J., and Thompson, J. 1992. Pancreatic Regeneration after partial pancreatectomy. 1992 Yearbook of Surgery. 435-437
  94. Selvanayagam, P., Graves, K., Cooper, C., and Rajaraman, S. 1991. Expression of the Parathyroid Hormone-Related Peptide Gene in Rat Tissues. Lab Invest. 64:713-717
  95. Brysk, M., Raimer, S., Pupo, R., Bell, T., and Rajaraman, S. 1991. Grafting of leg ulcers with undifferentiated keratinocytes. J Am Acad Dermatol. 25:238-244
  96. Brysk, M., Bell, T., and Rajaraman, S. 1991. Sensitivity of Desquamin to Proteolytic degradation. Pathobiology. 59:109-112
  97. Parekh, D., Townsend, C., Rajaraman, S., Ishizuka, J., and Thompson, J.C. 1991. Pancreatic Regeneration after partial Pancreatectomy. Am J Surg. 161:84-89
  98. Narayan, S., Draviam, E., Rajaraman, S., and Singh, P. 1991. High-affinity binding sites for bombesin on mouse colonic mucosal membranes. Mol Cell Biochem. 106:31-39
  99. Evers, M., Ishizuka, J., Townsend, C., Rajaraman, S., and Thompson, J.C. 1991. Expression of Neurotensin Messenger RNA in a human carcinoid tumor. Ann Surg. 214:448-455
  100. Parekh, D., Ishizuka, J., Townsend, C., Haber, B., Beauchamp, D., Rajaraman, S., Karp, G., Hsieh, J. and Thompson, J. 1991. Differential effects of Sodium Butyrate and Hexamethylene Bisacetamide on Growth and Secretion of Cultured Human Endocrine Tumor Cells. Arch Surg 126:467-472.
  101. Mumtaz, M., Farooqui, M., Ghanayem, B., Rajaraman, S., Frankenberg, L., and Ahmed, A. 1991. Studies on the mechanism of urotoxic effects of N,N' -Dimethylaminopropionitrile in rats and mice. 1. Biochemical and morphologic characterization of the injury and its relationship to metabolism. J Toxicol Environ Health. 33:1-17
  102. Poston, G., Draviam, E., Seitz, P., Rajaraman, S., Alexander, R., Cooper, C., Townsend, C., and Thompson, J.C. 1991. Expression of cholecystokinin forms by medullary thyroid cancer. Int J Cancer. 48:689-692
  103. Cleveland, M., Bakos, M., Pyron, D., Rajaraman, S., and Goldblum, R. 1991. Characterization of secretory component in amniotic fluid. Identification of new forms of secretory IgA. J Immunol. 147:181-188
  104. Evers, B.M., Townsend, C., Upp, J.R., Allen, E., Hurlbut, S.C., Kim, S.W., Rajaraman, S., Singh, P., Reubi, J.C. and Thompson, J.C. 1991. Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth. Gastroenterology. 101:303-311
  105. Cooper, C., Seitz, P., McPherson, M., Selvanayagam, P., and Rajaraman, S. Effects of Parathyroid Hormonal Peptides on the gut. In, Morii, H (ed): Calcium - Regulating Hormones II. Calcium Transport, Bone Metabolism, and New Drugs. Contrib Nephrol. Basel, Karger, 91:25-31, 1991
  106. Brysk, M., Bell, T., Hoida, C., Tyring, S. and Rajaraman, S. 1991. Interferon-gamma Modulates Terminal Differentiation and the Expression of Desquaminin Cultured Keratinocytes. Exp Cell Research. 197:140-147
  107. Cooper, C., Seitz, P., McPherson, M., Selvanayagam, P., and Rajaraman, S. Interrelationships between the stomach and Ca-regulating hormones. In, Hakanson, R. and Sundler, F. (Eds). The stomach as an endocrine organ. Elsevier Science Publishers (Biomedical Division). Amsterdam. pp. 351-371, 1991
  108. Gupta, V., Rajaraman, S., and Eberle, R. 1990. Spontaneous induction of malignancy in mouse cells by a human small cell lung cancer implanted in nude mice. Carcinogenesis. 11:713-722
  109. Poston, G. J., Townsend, Jr., C.M. Rajaraman, S., Thompson, J.C., and Singh, P. 1990. Effect of somatostatin and tamoxifen on the growth of human pancreatic cancers in mice. Pancreas. 5:151-157
  110. Cooper, C.W., Mok, L., Seitz, P.K., Rajaraman, S. and Thompson, J.C. 1990. Actions of Parathyroid Hormone on the Gut. In: Thompson, J.C., (Ed.) Gastrointestinal Endocrinology: Receptors and Post-Receptor Mechanisms. Academic Press, Inc., San Diego, California. 433-443
  111. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1990. Idiopathic hypercalciuria: Association with isolated hematuria and risk of urolithiasis in children. Kidney.Int. 37:807-811
  112. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1990. A clinicopathologic study of 24 children with hemolytic uremic syndrome. Pediatri. Nephrol. 4:52-60
  113. Gomez, G., Townsend, Jr., C.M., Green, D.W., Rajaraman, S., Uchida, T., Greeley, Jr., G.H., Soloway, R.D., and Thompson, J.C. 1990. Protective Action of Luminal Bile Salts in Necrotizing Acute Pancreatitis in Mice. J Clin Invest. 86:323-331
  114. Gomez, G., Townsend, Jr., C.M., Green, D.W., Rajaraman, S., Greeley, Jr., G.H., and Thompson, J.C. 1990. Reduced cholecystokinin mediates the inhibition of pancreatic growth induced by bile salts. Am J Physiol. 259:G86-G92
  115. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1989. Renal cystic disease of infancy. Results of histochemical studies. Pediatr Nephrol. 3:37-42.
  116. Mushtaha, A., Schmalsteig, F., Hughes, T., Rajaraman, S., Rudloff, H., and Goldman, A. 1989. Chemokinetic agents for monocytes in human milk: Possible role of tumor necrosis factor-alpha. Pediatr Res. 25:629-633.
  117. Evers, M., Gomez, G., Townsend, C., Rajaraman, S., and Thompson, J. 1989. Endogenous cholecystokinin regulates growth of human cholangiocarcinoma. Ann Surg. 210:317-323.
  118. McMillan, T., Calhoun, K., Mader, J., Stiernberg, C. and Rajaraman, S. 1989. The effect of hyperbaric oxygen therapy on oral cavity carcinoma. Laryngoscope. 99:241-244
  119. Brysk, M., Rajaraman, S., Penn, P., Barlow, W., and Bell, T. 1989. Cohesive properties of terminally differentiated keratinocytes. Expl Cell Biol. 57:60-66.
  120. Brysk, M.M., Newton, R.C., Rajaraman, S., Plott, T., Barlow, E., Bell, T., Penn, P., and Smith, E.B. 1989. Repigmentation of vitiliginous skin by cultured cells. Pigment Cell Res. 2:202-207.
  121. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1989. Acute tubulointerstitial nephritis in children: Clinical, morphologic and lectin studies. Am J Kidney Dis. 14:466-471
  122. Plott, T.R., Brysk, M.M., Newton, R. N., Raimer, S.S., and Rajaraman, S. 1989. A surgical treatment for Vitiligo. J Derm Surg Oncology. 15:1161-1166
  123. Gomez, G., Townsend, C., Green, D., Rajaraman, S., Uchida, T., and Thompson, J.C. 1989. Involvement of cholecystokinin receptors in the adverse effect of glucocorticoids on diet-induced necrotizing pancreatitis. Surgery. 105:230-238.
  124. Guo, Y., singh, P., Gomez, G., Rajaraman, S., Thompson, J.C. 1989. Contractile response of canine gallbladder and sphincter of Oddi to substance P and related peptides in vitro. Digestive Dis Sci. 34:812-817.
  125. Enriquez, J.L., Rajaraman, S., Kalia, A., Brouhard, B.H., and Travis, L.B. 1989. Isolated antinuclear antibody-negative lupus nephropathy in young children. Child Nephrol Urol. 9:340-346
  126. Brysk, M., Rajaraman, S., Penn, P., and Barlow, E. 1988. Glycoproteins modulated adhesion in terminally differentiated Keratinocytes. Cell Tissue Res. 253:657-663.
  127. Upp, J.R., Beauchamp, R.D., Townsend, C.M., Barranco, S.C., Singh, P., Rajaraman, S., James, E., and Thompson, J.C. 1988. Inhibition of human gastric adenocarcinoma xenograft growth in nude mice by alpha-difluoromethylornithine. Cancer Res. 48:3265-3269.
  128. Upp, J.R., Trudel, J.L., Townsend, C.M., Alexander, R.W., Rajaraman, S., Nealon, W.H., Greeley, G.H., and Thompson, J.C. 1988. Establishment of a human gastrinoma in nude mice. Surgery. 104:1037-1045.
  129. Brysk, M., Barlow, E., Bell, T., Rajaraman, S., and Stach, R.W. 1988. Purification of proteins from polyacrylamide gels, free of detergent or dye. Preparative Biochem. 18:217-228.
  130. Ozkaragoz, F., Rudloff, B., Rajaraman, S., Mushtaha, A.A., Schmalsteig, F.C., and Goldman, A.J. 1988. The motility of human mild macrophages in collagen gels. Pediatr Res. 23:449-452.
  131. Gupta, V., Rajaraman, S., and Costanzi, J.J. 1987. Effect of oxygen on the clonal growth of adherent cells (CFU-F) from different compartments of mouse bone marrow. Exp Hematol. 15:1153-1157.
  132. McCarty, T.M., Rajaraman, S., Elder, F.F.B., Gadson, P., and Thompson, E.B. 1987. Establishment and characterization of a human myeloid cell line from Philadelphia chromosome-negative myeloblastic leukemia arising in a patient with myelodysplastic syndrome. Blood. 70:1665-1672.
  133. Juneja, H.S., Elder, F.F.B., and Rajaraman, S. 1987. Acute monoblastic leukemia with a single chromosomal rearrangement involving breakpoints on chromosomes 8 and 16, 46, XX, 5(8;16)(p11;p13). Acta Haematol. 78:1-5.
  134. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1987. Polycystic kidney disease in the first year of life. J. Pediatrics. 111:693-699.
  135. Juneja, H.S., Rajaraman, S., Alperin, J.B., and Bainton, D.F. 1987. Auer rod-like inclusions in prolymphocytic leukemia. Acta Haematol. 77:115-119.
  136. Upp, Jr., J.R., Ishizuka, J., Lobe, T.E., Rajaraman, S., Townsend, Jr., C.M., and Thompson, J.C. 1987. Somatostatin secretion in cultured human islet cells from patients with nesidioblastosis: A compensatory mechanism? J Pediat Surgery. 22:1185-1186.
  137. Poston, C.J., Seltz, P.K., Townsend, C.M., Alexander, R.W., Rajaraman, S., Cooper, C.W., and Thompson, J.C. 1987. Calcitonin gene-related peptide: possible tumor marker for medullary thyroid cancer. Surgery. 102:1049-1054
  138. Kantak, A.G., Goldblum, R.M., Schwartz, M.Z., Rajaraman, S., Ladoulis, C.T., and Goldman, A.S. 1987. Fetal intestinal transplants in syngeneic rats: A developmental model of intestinal immunity. J Immunol. 138:3191-3196.
  139. Gonzalez, E.B., Swedo, J.L., Rajaraman, S., Daniels, J.C., and Grant, J.A. 1987. Ultrastructural and immunohistochemical evidence for release of eosinophilic granules in vivo: Cytotoxic potential in chronic eosinophilic pneumonia. J Allergy Clin Immunol. 79:755-762.
  140. Brouhard, B.H., Rajaraman, S., and LaGrone, L.F. 1987. Effect of varied protein intake on the nephropathy of the diabetic mouse (C57BL/s J db/db). Int J Ped Nephrol. 8:59-68.
  141. Rajaraman, S., Schmalsteig, F.C., Brysk, M.M., Hendrick, S.J., and Solomon, A.R. 1987. Aberrant expression of a chemokinetic glycoprotein in psoriatic skin. J Clin and Lab Immunol. 23:39-43.
  142. Gupta, V., Rajaraman, S., Gadson, P., and Costanzi, J.J. 1987. Primary transfection as a mechanism for transformation of host cells by human tumor cells implanted in nude mice. Cancer Res. 47:5194-5201.
  143. Lobe, T.E. and Rajaraman, S. 1986. Wilm's tumor and focal glomerular sclerosis (FGS). Report of a Case. In "Malignant Tumors of Childhood", First Edition, Benjy Frances Brooks (Ed.), pp. 32-22, Austin, Texas, University of Texas Press.
  144. Rajaraman, S., Goldblum, R.M., and Cavallo, T. 1986. IgA-Associated Glomerulonephri-tides: A study with monoclonal antibodies. Clin Immunol Immunopathol. 39:514-522.
  145. Brysk, M., Miller, J., Chen, S-J., and Rajaraman, S. 1986. Modified distribution of epidermal glycoproteins in the nude mouse. Exp Cell Biol. 54:163-169.
  146. (Rajaraman, S., Participant and Writing Committee Member) Southwest Pediatric Nephrol-ogy Study Group. 1986. Comparison of idiopathic and systemic lupus erythematosus associated membranous glomerulonephropathy in children. Am J Kidney Dis. 7:115-124.
  147. Solomon, A.R., Kantak, A.G., Ramirez, J.E., Rajaraman, S., Raimer, S.S., and Goldman, A.S. 1986. Suppressor-cytotoxic T-lymphocyte panniculitis. Pediatr Dermatol. 3:295-299
  148. Chen, S-J., Rajaraman, S., Miller, J., Kalmaz, G.D., and Brysk, M. 1986. Isolation and characterization of a 30 KDa membrane glycoprotein from human stratum corneum. Biochem et Biophys Acta. 881:375-382.
  149. Powell, L.D., Dinh, T.V., Rajaraman, S., Hannigan, E.V., Dillard, E.A., Yandell, R.B., and Tonia, T. 1986. Carcinoma in situ of the vulva: A clinicopathologic study of 50 cases. J Reprod Med. 31:808-814.
  150. Juneja, H.S., Rajaraman, S., Ramsey, K.M., and Elder, F.F.B. 1986. Role of marrow stromal cells in the establishment of a transformed lymphoblastic B-cell line from a normal human subject. Leuk Res. 10:1209-1219.
  151. Brysk, M.M., Rajaraman, S., Penn, P., and Chen, S-J. 1986. Endogenous lectin from terminally differentiated epidermal cells. Differentiation. 32:230-237.
  152. Christie, J.D., Rakusan, T.A., Martinez, M.A., Lucia, H.L., Rajaraman, S., Edwards, S.B., and Hayden, C.K. 1986. Hydranencephaly caused by congenital infection with herpes simplex virus. Pediatr Inf Dis. 5:373-378.
  153. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1985. A clinico-pathologic study of crescentic glomerulonephritis in 50 children. A report of the Southwest Pediatric Nephrology Study Group. Kidney Int. 27:450-458.
  154. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1985. Focal Segmental glomerulosclerosis in children with idiopathic nephrotic syndrome. A report of the Southwest Pediatric Nephrology Study Group. Kidney Int. 27:442-449.
  155. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1985. Association of IgA nephropathy with steroid-responsive nephrotic syndrome. A report of the Southwest Pediatric Nephrology Study Group. Am J Kidney Dis. 5:157-164.
  156. DeCastro, P., Jorizzo, J.L., Rajaraman, S., Solomon, A. R., Briggaman, R.A., and Raimer, S.S. 1984. Localized vulvar pemphigoid in a child. Pediatr Dermatol. 2:302-307, 1985.
  157. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1985. Dense deposit disease in children: Prognostic value of clinical and pathologic indicators. Am J Kidney Dis. 6:161-169.
  158. Gallardo, R.L., Juneja, H.S., Gardner, F.H., and Rajaraman, S. 1985. Normal human marrow stromal cells induce clonal growth of human malignant T-lymphoblasts. Int. J. Cell Cloning. 3:169-175.
  159. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Group. 1985. Hepatitis B surface antigenemia in North American children with membranous glomerulonephropathy. A report of the Southwest Pediatric Nephrology Study Group. J Pediat. 106:571-578.
  160. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1984. IgA nephropathy: Natural history and prognostic indices in children. Contr Nephrol. 40:214-221.
  161. Rajaraman, S., Pinto, J.A., and Cavallo, T. 1984. Glomerulonephritis with coexistent immune deposits and antibasement membrane activity. J Clin Path. 37:176-181.
  162. Cavallo, T., Pinto, J.A., and Rajaraman, S. 1984. Immune complex disease complicating diabetic glomerulosclerosis. Am J Nephrol. 4:347-354.
  163. Rajaraman, S. and Slavin, R.E. 1983. Correspondence. Intermediate filaments and tumor diagnosis. Lab Invest. 49:412-413.
  164. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1983. Childhood nephrotic syndrome associated with diffuse mesangial hypercellularity. A report of the Southwest Pediatric Nephrology Study Group. Kidney Int. 23:87-94.
  165. Barna, B.P., Makker, S., Kallen, R., Valenzuela, R., Deodhar, S.D., Yelp, M., Leto, D., Verbic, M.A., Rajaraman, S., and Govindarajan, S. 1983. A lymphocytotoxic factor (s) in plasma of patients with minimal change nephrotic syndrome: partial characterization. Clin Immunol Immunopathol. 27:272-282.
  166. Ramirez, F., Travis, L.B., Cunningham, R.J., Cavallo, T., Rajaraman, S., Brouhard, B.H., and Ellis, E. 1982. Focal segmental glomerulosclerosis, crescents and rapidly pro- gressive renal failure. Int J Ped Nephrol. 3:175-178.
  167. (Rajaraman, S., Participant) Southwest Pediatric Nephrology Study Group. 1982. A multicenter study of IgA nephropathy in children. Kidney Int. 22:643-652.
  168. Fish, J.C., Flye, M.W., William, A., Townsend, Jr., C.M., Rajaraman, S., Hokanson, J.A., Sarles, H.E., Bell, J.D., and Remmers, Jr., A.R. 1982. Inability of thoracic duct drainage to prevent hyperacute rejection. Transplantation. 36:134-139.
  169. Gupta, M.K., Rajaraman, S., Gupta, S.K., Hewitt, C.B., and Deodhar, S.D. 1981. Immunochemical Measurement of Serum Prostatic Acid Phosphatase (PAP). Clinical Evaluation of Radioimmunoassay and Counter Immunoelectrophoresis. Am J Clin Pathol. 76:430-436.
  170. Rajaraman, S., Deodhar, S.D., Carey, W.D., and Salanga, V.D. 1980. Hashimoto's Thyroiditis, Primary Biliary Cirrhosis, and Myasthenia Gravis. Am J Clin Pathol. 74:831-834.
  171. Al-Mefty, O., Marano, G., Rajaraman, S., Nugent, G.R., and Rodman, N.F. 1979. Transient ischemic attacks due to increased platelet aggregation and adhesiveness. Ultrastructural and functional correlation. J Neurosurg. 50:449-453.

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