Pharmacology and Toxicology - Faculty
Fernanda Laezza, M.D., Ph.D.
Phone: (409) 772-9672
Fax: (409) 772-9642
Research Information Page
1991, Medical Doctor, Universita` degli Studi di Torino (Italy)
2000, Ph. D. Neuroscience, Emory University, Atlanta, GA
After obtaining a MD degree at the University of Turin in Italy, Dr. Laezza came to the USA as a neuroscience graduate student at Emory University with Raymond Dingledine. Her work as a graduate student focused on the role of the GluA2 lacking glutamate receptors in the induction of synaptic plasticity in the hippocampal circuit. Her interest for the physiology of ion channels and their relationship to excitability and synaptic transmission brought her to Washington University in St. Louis where she conducted her post-doctoral training, initially with Ann Marie Craig and later on with David Ornitz and Jeanne Nerbonne, and developed an interest in voltage-gated sodium channels. Since the end of 2008, she has been Assistant Professor in the Department of Pharmacology & Toxicology at UTMB where she has been establishing a research program focusing on the regulation of neuronal voltage-gated sodium channels by protein:protein interaction. Her research goals are to: i) develop new approaches to study macromolecular complexes within ion channels in vivo; ii) discover new intracellular signaling pathways at the basis of neuronal excitability; iii) design chemical- or gene-based approaches towards the treatment of human channelopathies and neurodegenerative disorders.