Pharmacology and Toxicology - Faculty



Jia Zhou, Ph.D.

Associate Professor

Contact Information

Phone: (409) 772-9748
Fax: (409) 747-7050
Email: Jizhou@utmb.edu

Research Information Page

Education

2009 Residential School on Medicinal Chemistry, Drew University, Madison, NJ (Chemistry and Biology in Drug Discovery)

1994-1997 Ph.D., 1997, College of Chemistry, Nankai University, Tianjin, China (Synthetic Organic Chemistry; Advisor: Professor Ruyu Chen, Academician of Chinese Academy of Sciences)

1991-1994 M.Sc., 1994, College of Chemistry, Nankai University, Tianjin, China (Synthetic Organic Chemistry; Advisor: Professor Ruyu Chen, Academician of Chinese Academy of Sciences)

1987-1991 B.Sc., 1991, Department of Chemistry, Central China Normal University, Wuhan, China (Chemistry)

Background

I received my Ph.D. in organic chemistry in 1997 from Nankai University, China. Then I joined the chemistry faculty in the same university and was promoted to Associate Professor there. In 1999, I started my postdoctoral training in organic chemistry with Dr. Sidney M. Hecht (now at ASU) in the Department of Chemistry at the University of Virginia. After further postdoctoral training in medicinal chemistry with Dr. Alan P. Kozikowski (now at UIC) in the Drug Discovery Program at the Georgetown University Medical Center, I moved to Acenta Discovery, Inc. as a Senior Scientist in 2003. In 2007, I joined PsychoGenics, Inc., a pharmaceutical company located in New York, as a Senior Principal Scientist.

After about 4 years of the postdoctoral training in both organic chemistry and medicinal chemistry in the Universities of US and 7 years of pharmaceutical industry experience in drug discovery and development, I joined the faculty of Chemical Biology Program, Department of Pharmacology and Toxicology at UTMB as an Assistant Professor in 2010. I am also a faculty member of the Center for Addiction Research (CAR) of UTMB. My research interests currently focus on the interface of synthetic organic chemistry and medicinal chemistry, and in particular on the drug discovery of bioactive small molecules as efficient therapies targeting a variety of central nervous system disorders and cancers, as well as the related chemical biology research. Our daily research efforts are heavily involved in lead compound-based or molecular mechanism-based rational drug design, chemical synthesis and optimization of new small molecules for the pharmacological evaluation and development. Our mission is to establish a strong and creative research program that applies state-of-the-art chemical approaches to biological problems impacting diagnosis, prevention and treatment of human diseases.