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The following research questions are currently under investigation:
| What are the molecular mechanisms controlling cell proliferation? |
| What mechanisms underlie tissue homeostasis? |
| By what mechanisms do nonsteroidal anti-inflammatory drugs injure the intestine? |
| How do signaling molecules such as protein kinases and GTP-binding proteins regulate various important cellular processes? |
| What neurotransmitters and receptors are involved in stress disorder, depression, and anxiety? |
| How to the actions of a psychosis-causing drug inform a strategy for treating schizophrenia? |
| Will early disease biomarkers provide superior modalities to monitor the at risk population? |
| How does exposure to environmental contaminants affect normal physiology and human health? |
| What are the molecular mechanisms involved in the role of the human placenta as a functional barrier regulating fetal exposure to medications and environmental toxins? |
| What are the preclinical and clinical investigations required to make an existing medication available for treatment of the pregnant addict to opiate and or nicotine? |
| What new strategies can target and treat metastatic cancer? |
| Can adipose stem cells be used to treat cancer? |
| How can nanoparticles improve drug delivery and pharmacokinetics? |
| What are the molecular and cellular mechanisms underlying synaptic transmission and excitability in the brain? |
| What new strategies are available to target neuronal ion channels for medication development? |
| Do neural pathways in the brain that are involved in drug addiction overlap with neural pathways that are involved in eating? |
| What mechanisms underlie the propensity to relapse to addiction during abstinence? |
| Which mechanistic targets hold promise in developing new medications for addiction? |