Graduate Education – Space Life Sciences
Faculty
 William Au
   

Present Position and Address

Professor

Division of Environmental Toxicology

Department of Preventive Medicine and Community Health

The University of Texas Medical Branch

Galveston, Texas 77555‑1110

E‑mail: william.au@utmb.edu

 

Director

International Science Outreach Program

Sealy Center for Environmental Health and Medicine

University of Texas Medical Branch

 

Chairman (since 1997)

Alexander Hollaender Committee for International Programs

Education

  • 1972, May; Biology B.A. University of North Carolina, Greensboro, North Carolina

  • 1977, May; Developmental Biology Ph.D. University of Cincinnati, Cincinnati, Ohio

Selected Peer-Reviewed Publications (in chronological order)

  1. Abdel-Rahman, S., Salama, A. S., Au, W.W., and Hamada, F.A. The role of polymorphic CYP2E1 and CYP2D6 genes in NNK-induced chromosome aberrations in cultured human lymphocytes. Pharmacogenetics, 10, 239-249, 2000.

  2. Au, W. W., Oh, H. Y., Salama, S., and Kietthubthew, S. Genetic susceptibility to environmental disease. NATO Science Series, Series A: Life Sciences – Vol. 313, 312 – 318, 2000.

  3. Au, W.W., Strategies for conducting human population monitoring studies. NATO Science Series, Series A: Life Sciences – Vol. 313, 86 - 93, 2000.

  4. Cebulska-Wailewska, A., Wierzewska, A., Dyga, W., Drag. Z., Siffel, C., Horvath, M., Au, W.W. Induction of DNA and cytogenetic damage in lymphocytes of Polish workers exposed to pesticides. Centrol Europ. J. Occup. Environ. Med. 6, 272 – 287, 2000.

  5. Salama, S.A., Sierra-Torres, C.H., Oh, H.Y., Hamada, F.A., and Au, W.W. Variant metabolizing gene alleles determine the genotoxicity of benzo(a)pyrene. Environ. Mol. Mutag., 37, 17 – 26, 2001.

  6. Kietthubthew, S., Hutcha, S., Au, W.W. Genetic and environmental interactions on oral cancer in southern Thailand. Environ. Mol. Mutag., 37, 111-116, 2001.

  7. Au, W. W., Oh, H.Y., Grady, J., Salama, S., Heo, M.Y. Usefulness of genetic susceptibility and biomarkers for evaluation of environmental health risk. Environ. Mol. Mutag., 37: 215-225, 2001.

  8. Au, W.W., Oberheitmann, B., Heo, M.Y., Hoffmann, W., and Oh, H.Y. Biomarker monitoring for health risk based on sensitivity to environmental mutagens. Reviews on Environ. Health 16, 41-64, 2001.

  9. Heo, M.Y., Sohn, S.J. Au, W.W. Antigenotoxicity of galangin as a cancer chemopreventive agent candidate. Mutat. Res. 488, 135-150, 2001.

  10. Moore, T.O., Yen-Moore, A., Carrasco, D., Straten, M.V., Arany, I., Au, W.W., Tyring, S. Human papillomavirus, smoking and cancer. J. Cutan. Med. Surg., 2001.

  11. Au, W.W. Life style factors and acquired susceptibility to environmental disease. Int. J. Hygiene and Env. Health 204, 17 – 22, 2001.

  12. Au, W. W.. Susceptibility of children to environmental toxic substances. Int. J. Hyg. Environ. Health, 205, 1-3, 2002.

  13. Bonassi, S., W. W. Au. Biomarkers in molecular epidemiology studies for health risk prediction. Mutat. Res., 511, 73-86, 2002.

  14. William W. Au, Henry Falk. Superfund Research Program – accomplishments and future opportunities. Int. J. Hyg. Environ. Health 205, 165-168, 2002.

  15. Salama A. Salama, William W. Au, Glenn C. Hunter, Richard G. Sheahan, Osama Badary, Ashraf B. Abdel-Naim, Farid M.A. Hamada. Polymorphic xenobiotics- metabolizing genes in susceptibility to atherosclerosis. Environ. Mol. Mutag., 40, 153-160, 2002.

  16. Au, WW, Oberheitmann, B, Harms, C. Assessing DNA damage and health risk using biomarkers. Mutat. Res., 407, 1-11, 2002.

  17. Carlos H. Sierra-Torres, William W. Au, Concepcion D. Arrastia, Nohelia Cajas- Salazar, Sonia C. Robazetti, Deborah A. Payne, Stephen K. Tyring. Polymorphisms for CYP2E1, GSTM1, and mEH, and the risk for cervical neoplasia. Environ. Mol. Mutagen., 41, 69-76, 2003.

  18. Cajas-Salazar N., Au, W. W., Zwischenberger, JB, Sierra-Torres, HS, Salama, SA, Alpard, SK, Tyring, SK. Effect of expoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer. Cancer Genetics Cytogenet., 145, 97-102, 2003.

  19. Salama A. Salama, William W. Au. Susceptibility and biomarker knowledge for improvement of environmental health. Int. J. Hyg. Environ. Health,206, 401-412, 2003.

  20. Kietthubthew, S., Sriplung H., Au, W.W., Ishida, T. The p53 codon 72 polymorphism and risk of oral cancer in Southern Thailand. Asian Pac J Cancer Prev 4, 209-214, 2003.

  21. Au, WW, Salama SA, Sierra-Torres, CH Functional characterization of polymorphisms in DNA repair genes using cytogenetic challenge assays. Environ Health Persp, 111, 1843-1850, 2003.

  22. Sierra-Torres CH., Tyring SJ., Au WW. Risk contribution of sexual behavior and cigarette smoking to cervical neoplasia. Int. J. Gynecol. Cancer 13, 617-625, 2003.

  23. Cajas-Salazar, N., Sierra-Torres, H., Salama, A.S., Zwischenberger, J.A., Au, W.W. Combined effect of MPO, GSTM1 and GSTT1 polymorphisms on chromosome aberrations and lung cancer risk. Int. J. Hygiene Env. Health, 206, 473-483, 2003.

  24. Au, W.W., Sierra-Torres, C.H., Tyring, S.K. Acquired and genetic susceptibility to cervical cancer. Mutat. Res., 544, 361-364, 2003.

  25. Au, W.W. Mutagen sensitivity assays in population studies. Mutat. Res., 544, 273-277, 2003.

  26. Au, W.W., Anwar, W., Sram, R.J., Chulasiri, M., Ribeiro, L.R. International conferences on environmental mutagens in human populations – opportunities, accomplishments and challenges. Mutat. Res., 544, 93-98, 2003.

  27. Au, W.W. Life style, environmental and genetic susceptibility to cervical cancer. Toxicology 198, 117-120, 2004.

  28. Harms, C., Salama, S.A., Sierra-Torres, C.H., Cajas-Salazar, N., Au, W.W. Polymorphisms in DNA repair genes, chromosome aberrations and lung cancer. Environ. Mol. Mutag., 44:74-82, 2004.

  29. Au, W.W., Navasumrit, P., Ruchirawat, M. Use of biomarkers to characterize functions of polymorphic DNA repair genotypes. Int. J. Hygiene Environ. Health, 207:301-313, 2004.

  30. Abida K. Haque, William Au, Nohelia Cajas-Salazar, Shilpi Khan, Andrew W. Ginzel, Brent A. Norris, Dennie V.Jones, Joseph B. Zwischenberger and Jingwu Xie. p53 Expression, CYP2E1 Polymorphism, Cigarette Smoking and Survival in Non-small Cell Lung Cancer - A Long Term Follow up Study. Appl. Immunohistochem. Mol. Morphol. 12, 315-322, 2004.

  31. Au, W.W. and Salama, SA. Cytogenetic challenge assays for assessment of DNA repair capacities. In: DNA Repair Protocols: Eukaryotic Systems. Editor: D Henderson. Humana Press.

  32. Ashley, B.C., Birchfield, P.T., Chamberlain, B.V., Kotwal, R.S., McClellan, S.F., Moynihan, S., Patni, S.B., Salmon, S.A., Au, W.W. Environmental health concerns from the consumption of irradiated food. Int. J. Hygiene Env. Health, 2004.

  33. Dao, D.D., Sierra-Torres, C.H., Robazetti, S.C., Naranjo de Gomez, M., Konig, R., Lester, J., Au, W.W., Tyring, S.K. HLA-DQB1 alleles and cervical cancer in Venezuela women. Gynecological Oncology, 2004.

  34. Au, W. W., Lee, E., Christiani, D.C. Biomarker research in occupational health. J. Occup. Environ. Med., 2004.

  35. Au, W.W. and Salama S.A. Use of Biomarkers to elucidate genetic susceptibility to environmental cancer. Environ. Mol. Mutag., 2004.

  36. Cebulska-Wasilewska, A., Panek, A., Zabinski, Z., Moszczynski, P., Au, W.W. Influence of occupational exposure to mercury vapour on genotoxicity and DNA repair. Mutat. Res., 2004.