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1. It is
recommended patients abstain from taking antibiotics or
bismuth salts for at least _______________ before endoscopy
procedure. Supression of H.pylori by these agents makes the
organism difficult to detect by any means, AND re-growth of H.
pylori may be patchy, leading to a false negative results in
the first few weeks after treatment.
three days
three weeks
three months
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2.
After insertion of specimen, CLOtest must remain at
temperatures between 30-40 celsius. CLOtests may not be
reported as negative before the _____ hour incubation period
is over
12
24
48
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3. CLOtest
is used in the detection of ____________ which has been shown
to be the main cause of chronic gastritis. A color change from
yellow to pink denotes the presence of this organism.
Proteus mirrabilis a
gram negative bacillus
Bacillus thuringensis,
a gram positive bacillus
Helicobacter pylori, a
gram negative bacillus
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4. A
fail-check must be performed on ALL NEGATIVE CLOtests. That is
if the gel is still yellow at 24 hours, A UREASE TABLET is
inserted to the CLOtest card. In order to comply with the
regulations, the results of this fail check must be documented
on the appropriate log.
TRUE
FALSE
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5. For
bloody biopsy samples, a color other than yellow may be seen
around the edge of the biopsy sample (after insertion). This
is NOT considered a positive test.
TRUE
FALSE
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6. A
positive CLOtest is depicted by the development of a
____________ color. Yellow is considered negative.
Orange
pink
magenta
all of the above
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7. The
following may be causes of false negatives:
Very low numbers of H.
pylori in the tissue sample
Patchy H. pylori distribution
so that the organism is not captured in the sample.
Recent ingestion of
antibiotics, bismuth, proton pump inhibitors, or sucralfate
which can inhibit the organism.
Formalin contamination of
the sample
Sample of intestinal
metaplasia -- (H. pylori does not colonize intestinal
mucosa)
All of the above
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