Course Descriptions
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MICR
6201 - Orientation
The
objective of this course is to allow the student to gain insight into
the ongoing research programs within the Microbiology and Immunology
program faculty laboratories. The student confers with individual
faculty members to learn research approaches and methodologies. The
course consists of conferences and demonstrations. Short introductions
to electronic-based literature searching, and access and manipulation
of information in electronic databases (e.g. Genbank) and statistics
are also included.
2
credits
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MICR
6006 - Laboratory
Rotations
This
course is designed to provide students with an opportunity to become
familiar with the faculty and their research by participating in the
activities of the laboratory (gaining supervised hands-on experience
with techniques and experimental protocols) and by becoming acquainted
with the laboratory staff and the goals of the research project.
Students will have opportunities for discussions with the instructor,
exposure to relevant literature and active participation in laboratory
procedures. The goal of this course is to provide exposure to a
variety of experimental approaches and to help in the identification
of a supervisory professor and dissertation project. Students are
required to provide a written summary of their activities at the end
of the term. Letter grades will be determined by the instructor and
will be based on the laboratory performance of the student.
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MICR
6408 - ADVANCED IMMUNOLOGY
An
in-depth study of the immune response and related events, with
emphasis on the mechanism of cellular and humoral immunity. Some of
the topics to be covered include antibody structure and function,
antigen-antibody reactions, cells involved in the immune response,
antibody formation, cellular immunity, mediators, tolerance, and
immunogenetics. Material will be presented in lectures and assigned
readings of texts, reviews, and research articles. Grading will be
based on written examinations and class participation. Teaching
is by lecture and discussion.
4
Credits
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MICR
6409 - DISEASE
MECHANISMS
The
course examines the principles of normal and abnormal body functions
at the molecular, cellular, tissue, organ and whole body levels. The
course will provide important background for studies of experimental
disease and also for research and interaction with physicians.
Teaching is conducted by research faculty from both the basic science
and clinical departments.
Hours
per week: Lecture, 4
4
Credits
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MICR
6403 - GENERAL VIROLOGY
Principles
and concepts of animal virology are introduced, but the majority of
the course is devoted to the study of viruses of medical importance.
Emphasis will be placed upon the chemical and physical characteristics
of viruses, mechanisms of replication, immunology, and pathogenesis.
The course consists of lectures and discussion periods.
4
Credits
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MICR
6315 - PATHOGENIC
BACTERIOLOGY
The
objective of this course is to introduce students to concepts of
research on bacterial pathogens.
Pathogens infecting man are studied with emphasis given to
their pathogenic mechanisms, induction of immunity, the genetic and
molecular basis of pathogenesis and physiochemical characteristics.
The course consists of lectures and discussions.
3 Credits
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MICR
6320 - MOLECULAR
AND MICROBIAL GENETICS
This
course provides a detailed study of the genetics of microorganisms.
Topics include: mechanism of conjugation, transduction,
transformation and recombination; plasmids and transposons;
recombinant DNA technology; and, regulation of gene expression in
prokaryotic and eukaryotic systems.
Teaching is by lecture and discussion.
3
credits.
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MICR
6425 - MOLECULAR BIOLOGICAL
TECHNIQUES
This
course emphasizes lecture and laboratory material to familiarize
students with modern molecular biological techniques.
The objectives are to provide the theoretical and biochemical
basis for commonly utilized molecular biological methods; to discuss
the in vivo functioning of
enzyme systems used in molecular biological techniques; and, to
discuss the use of molecular biological techniques in the approach of
outstanding problems in biomedical science.
The course is structured with six laboratory hours to provide
hands-on experience, one lecture hour, and one discussion hour per
week to analyze laboratory results.
4 Credits.
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MICR
6195 - STUDENT
SEMINAR
This
course provides an opportunity for the student to gain experience in
literature research, literature analysis and oral presentation. Students present at least one current research paper from the
literature.
1
credit.
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MICX
6000 - SPECIAL TOPICS
The
objective of this course is to offer tutorial study for the student in
a specialized field of microbiology.
The specialized field is determined by the faculty member
involved and the individual student.
The course consists of laboratory work, conferences and
assigned readings.
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MICR
6097 - RESEARCH
Research
involves work designed to introduce the student to the techniques and
philosophy of scientific research and to guide the student to the
development of a research problem in the major area of concentration.
A maximum of nine hours is creditable toward a degree program.
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MICR
6398 - THESIS
Our
program requires formal preparation and completion of the thesis for
the Master of Science degree under the direction of the student's
supervisory committee. A
publication may be substituted for thesis.
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MICR
6399 - DISSERTATION
Formal
preparation and completion of the dissertation for the Doctor of
Philosophy degree under the direction of the student's supervisory
committee is required.
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HBCG
XXXX
- ADVANCES
IN STRUCTURAL BIOLOGY
Modern methods on Nuclear Magnetic Resonance (NMR) spectroscopy, X-ray
diffraction and computational methods will be used to understand the
structure and dynamics of biological macromolecules. Theory and
applications of multidimensional and multinuclear NMR of proteins,
nucleic acids and their complexes will be described. Theory and
applications of X-ray crystallographic techniques will be also
provided. Molecular mechanisms and dynamics, molecular modeling and
structural prediction methods will be used in conjunction with the NMR
and X-ray crystallographic experimental methods. Grades will be based
upon exams in each of the three segments (NMR, X-ray and computation
methods) of the course.
Course
coordinator: Gorenstein
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