"Newer" Antidepressant Classes
For the purpose of this lesson, we will divide discussion of the antidepressants into two classes -- the "reuptake inhibitors" (which inhibit the reuptake of the monoamines serotonin, dopamine, and norepinephrine) and the "receptor modulators", which work directly on the receptors.
The "reuptake inhibitors" include the following:
| SSRI (selective serotonin reuptake inhibitor) |
SNRI (serotonin norepinephrine reuptake inhibitor) |
NDRI (norephinephrine dopamine reuptake inhibitor) |
|---|---|---|
|
Fluoxetine (Prozac) |
venlafaxine (Effexor) |
bupropion (Wellbutrin) |
|
Sertraline (Zoloft) |
desvenlafaxine (Pristiq) |
|
|
Fluvoxamine (Luvox) |
duloxetine (Cymbalta) |
|
|
Paroxetine (Paxil) |
||
|
Citalopram (Celexa) |
||
|
Escitalopram (Lexapro) |
The "receptor modulators" include the following
| SARI (Serotonin-2 antagonist/reuptake inhibitor) | NaSSA (Norepinephrine/Serotonin specific antagonist) |
|---|---|
| Nefazadone | Mirtazapine (Remeron) |
| Trazadone (Desyrel) |
