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Faculty Investigator

Maki Wakamiya, PhD

Maki Wakamiya, Ph.D.

Sealy Center for Cancer Cell Biology
email: mawakami@utmb.edu

My primary role at Sealy Center for Cancer Cell Biology is to direct Transgenic Mouse Core Facility.  The mission of the Transgenic Mouse Core Facility is to facilitate the advancement of animal model studies in UTMB.  Our primary functions are 1) to generate transgenic and knockout mice that can serve as in vivo models for addressing a wide variety of biological questions, and 2) to preserve valuable mouse strains as safeguards to prevent the accidental loss due to natural disaster, human error, or infection; and to discontinue maintenance of a stock.

Transgenic Mouse Core Facility is supported by the Sealy Center for Cancer Cell Biology and available for use by all scientists.  The facility is located inside the ARC within Medical Research Building, and currently staffed by Research Associate San F. Yang and myself.  

My own research focuses on early embryonic development in vertebrates, particularly of the mouse.  We genetically engineer mice, and use them to elucidate fundamental processes in embryogenesis, such as early cell-lineage specification, and gastrulation.  At present, we study the function of Sca10 gene in embryonic stem cell differentiation.  Understanding how the specific cell types are established and maintained during embryogenesis also contributes to understanding the mechanisms underlying tumorigenesis.

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Last reviewed: November 5, 2008.