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Scientific Publications

The UTMB OAIC Pepper Center Investigators have authored hundreds of scientific articles:


2010 Pepper Center Publications
  1. Al Snih S, Graham JE, Kuo YF, Goodwin JS, Markides KS, Ottenbacher KJ. Obesity and disability: relation among older adults living in Latin America and the Caribbean. Am J Epidemiol. Jun 15 2010;171(12):1282-1288, PMID: 20472569, PMCID: PMC2915495.
  2. Anderson JF, Siller E, Barral JM. The sacsin repeating region (SRR): a novel Hsp90-related supra-domain associated with neurodegeneration. J Mol Biol. Jul 23 2010;400(4):665-674, PMID: 20488193.
  3. Beard HA, Markides KS, Al Ghatrif M, Kuo YF, Raji MA. Trends in diabetes medication use and prevalence of geriatric syndromes in older Mexican Americans from 1993/1994 to 2004/2005. Ann Pharmacother. Sep 2010;44(9):1376-1383, PMID: 20628044, PMCID: PMC3032629.
  4. Borsheim E, Chinkes DL, McEntire SJ, Rodriguez NR, Herndon DN, Suman OE. Whole body protein kinetics measured with a non-invasive method in severely burned children. Burns. Nov 2010;36(7):1006-1012, PMID: 20392565, PMCID: PMC2948638.
  5. Cree MG, Paddon-Jones D, Newcomer BR, Ronsen O, Aarsland A, Wolfe RR, Ferrando A. Twenty-eight-day bed rest with hypercortisolemia induces peripheral insulin resistance and increases intramuscular triglycerides. Metabolism. May 2010;59(5):703-710, PMID: 19919871, PMCID: PMC2856785.
  6. Dillon EL, Durham WJ, Urban RJ, Sheffield-Moore M. Hormone treatment and muscle anabolism during aging: androgens. Clin Nutr. Dec 2010;29(6):697-700, PMID: 20452103, PMCID: PMC2964430.
  7. Dreyer HC, Fujita S, Glynn EL, Drummond MJ, Volpi E, Rasmussen BB. Resistance exercise increases leg muscle protein synthesis and mTOR signalling independent of sex. Acta Physiol (Oxf). May 2010;199(1):71-81, PMID: 20070283, PMCID: PMC2881180.
  8. Drummond MJ. MicroRNAs and exercise-induced skeletal muscle adaptations. J Physiol. Oct 15 2010;588(Pt 20):3849-3850, PMID: 20952375, PMCID: PMC3000575.
  9. Drummond MJ, Conlee RK, Mack GW, Sudweeks S, Schaalje GB, Parcell AC. Myogenic regulatory factor response to resistance exercise volume in skeletal muscle. Eur J Appl Physiol. Mar 2010;108(4):771-778, PMID: 20187282.
  10. Drummond MJ, Glynn EL, Fry CS, Timmerman KL, Volpi E, Rasmussen BB. An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle. Am J Physiol Endocrinol Metab. May 2010;298(5):E1011-1018, PMID: 20304764, PMCID: PMC2867366.
  11. Durham WJ, Casperson SL, Dillon EL, Keske MA, Paddon-Jones D, Sanford AP, Hickner RC, Grady JJ, Sheffield-Moore M. Age-related anabolic resistance after endurance-type exercise in healthy humans. FASEB J. Oct 2010;24(10):4117-4127, PMID: 20547663, PMCID: PMC2996901.
  12. English KL, Paddon-Jones D. Protecting muscle mass and function in older adults during bed rest. Curr Opin Clin Nutr Metab Care. Jan 2010;13(1):34-39, PMID: 19898232, PMCID: PMC3276215.
  13. Ferrando AA, Paddon-Jones D, Hays NP, Kortebein P, Ronsen O, Williams RH, McComb A, Symons TB, Wolfe RR, Evans W. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clin Nutr. Feb 2010;29(1):18-23, PMID: 19419806.
  14. Fisher SR, Kuo YF, Graham JE, Ottenbacher KJ, Ostir GV. Early ambulation and length of stay in older adults hospitalized for acute illness. Arch Intern Med. Nov 22 2010;170(21):1942-1943, PMID: 21098357, PMCID: PMC3136816.
  15. Fry CS, Glynn EL, Drummond MJ, Timmerman KL, Fujita S, Abe T, Dhanani S, Volpi E, Rasmussen BB. Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men. J Appl Physiol. May 2010;108(5):1199-1209, PMID: 20150565, PMCID: PMC2867530.
  16. Glynn EL, Fry CS, Drummond MJ, Dreyer HC, Dhanani S, Volpi E, Rasmussen BB. Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise. Am J Physiol Regul Integr Comp Physiol. Aug 2010;299(2):R533-540, PMID: 20519362, PMCID: PMC2928613.
  17. Glynn EL, Fry CS, Drummond MJ, Timmerman KL, Dhanani S, Volpi E, Rasmussen BB. Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women. J Nutr. Nov 2010;140(11):1970-1976, PMID: 20844186, PMCID: PMC2955876.
  18. Graham JE, Fisher SR, Berges IM, Kuo YF, Ostir GV. Walking speed threshold for classifying walking independence in hospitalized older adults. Phys Ther. Nov 2010;90(11):1591-1597, PMID: 20705685, PMCID: PMC2967707.
  19. Hsieh CC, Kuro-o M, Rosenblatt KP, Brobey R, Papaconstantinou J. The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging. Aging (Albany NY). Sep 2010;2(9):597-611, PMID: 20844314, PMCID: PMC2984608.
  20. Kuo YF, Goodwin JS. Effect of hospitalists on length of stay in the medicare population: variation according to hospital and patient characteristics. J Am Geriatr Soc. Sep 2010;58(9):1649-1657, PMID: 20863324, PMCID: PMC2946246.
  21. Liu H, Chen SE, Jin B, Carson JA, Niu A, Durham W, Lai JY, Li YP. TIMP3: a physiological regulator of adult myogenesis. J Cell Sci. Sep 1 2010;123(Pt 17):2914-2921, PMID: 20682640, PMCID: PMC2923569.
  22. Papaconstantinou J, Hsieh CC. Activation of senescence and aging characteristics by mitochondrially generated ROS: how are they linked? Cell Cycle. Oct 1 2010;9(19):3831-3833, PMID: 20890113, PMCID: PMC2975432.
  23. Phillips MD, Flynn MG, McFarlin BK, Stewart LK, Timmerman KL. Resistance training at eight-repetition maximum reduces the inflammatory milieu in elderly women. Med Sci Sports Exerc. Feb 2010;42(2):314-325, PMID: 19927028.
  24. Sharma G, Kuo YF, Freeman J, Zhang DD, Goodwin JS. Comanagement of hospitalized surgical patients by medicine physicians in the United States. Arch Intern Med. Feb 22 2010;170(4):363-368, PMID: 20177040, PMCID: PMC2843086.
  25. Sharma G, Kuo YF, Freeman JL, Zhang DD, Goodwin JS. Outpatient follow-up visit and 30-day emergency department visit and readmission in patients hospitalized for chronic obstructive pulmonary disease. Arch Intern Med. Oct 11 2010;170(18):1664-1670, PMID: 20937926, PMCID: PMC2977945.
  26. Siller E, DeZwaan DC, Anderson JF, Freeman BC, Barral JM. Slowing bacterial translation speed enhances eukaryotic protein folding efficiency. J Mol Biol. Mar 12 2010;396(5):1310-1318, PMID: 20043920.
  27. Starr ME, Ueda J, Takahashi H, Weiler H, Esmon CT, Evers BM, Saito H. Age-dependent vulnerability to endotoxemia is associated with reduction of anticoagulant factors activated protein C and thrombomodulin. Blood. Jun 10 2010;115(23):4886-4893, PMID: 20348393, PMCID: PMC2890181.
  28. Stowe RP, Peek MK, Cutchin MP, Goodwin JS. Plasma cytokine levels in a population-based study: relation to age and ethnicity. J Gerontol A Biol Sci Med Sci. Apr 2010;65(4):429-433, PMID: 20018825, PMCID: PMC2844059.
  29. Stowe RP, Peek MK, Perez NA, Yetman DL, Cutchin MP, Goodwin JS. Herpesvirus reactivation and socioeconomic position: a community-based study. J Epidemiol Community Health. Aug 2010;64(8):666-671, PMID: 19825788, PMCID: PMC4006958.
  30. Szczesny B, Tann AW, Mitra S. Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: Susceptibility of skeletal muscles to oxidative injury. Mech Ageing Dev. May 2010;131(5):330-337, PMID: 20363243, PMCID: PMC2883317.
  31. Timmerman KL, Lee JL, Dreyer HC, Dhanani S, Glynn EL, Fry CS, Drummond MJ, Sheffield-Moore M, Rasmussen BB, Volpi E. Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling. J Clin Endocrinol Metab. Aug 2010;95(8):3848-3857, PMID: 20484484, PMCID: PMC2913031.
  32. Timmerman KL, Lee JL, Fujita S, Dhanani S, Dreyer HC, Fry CS, Drummond MJ, Sheffield-Moore M, Rasmussen BB, Volpi E. Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adults. Diabetes. Nov 2010;59(11):2764-2771, PMID: 20724580, PMCID: PMC2963534.
  33. Vasileiadou K, Pantazidis G, Papadopoulou K, Ligoudistianou C, Kourelis A, Petrakis S, Masmanidou E, Testa T, Kourounakis AP, Hadjipetrou L, Papaconstantinou J, Yiangou M. α1-Acid glycoprotein production in rat dorsal air pouch in response to inflammatory stimuli, dexamethasone and honey bee venom. Experimental and Molecular Pathology. 8// 2010;89(1):63-71, PMCID: PMC2900460.
  34. Wilkinson GS, Baillargeon J, Kuo YF, Freeman JL, Goodwin JS. Atrial fibrillation and stroke associated with intravenous bisphosphonate therapy in older patients with cancer. J Clin Oncol. Nov 20 2010;28(33):4898-4905, PMID: 20940190, PMCID: PMC3020695.



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