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Robin Stephens, Ph.D.
Associate Professor, Division of Infectious Diseases

Robin Stephens, Ph.D., Associate Professor

Robin Stephens, Ph.D.
Associate Professor
Department of Internal Medicine
Division of Infectious Diseases

University of Texas Medical Branch
301 University Blvd, Marvin Graves Bldg., Rm 4.210D
Galveston, Texas 77555-0435
Phone: 409.747.1860
Fax: 409.772.6527
Email: rostephe@utmb.edu


Degree/Training Completed Year Name & Location
B.A. 1993 Cornell University Ithaca, NY
M.D. 1997 New York University, New York, NY
Ph.D 2001 Washington University, St. Louis, MO
Postdoctoral 2010 National Institute for Medical Research, London, England


Malaria still kills 0.8 million people a year, mostly children in sub-Saharan Africa. Vaccine work has entered a very hopeful stage, but very little is known about the factors determining immunity to this parasitic disease. Work in our laboratory focuses on the immunology and pathology of malaria infection. CD4 + Memory T and B cells are essential for effective immunity, however there are many aspects of their development and maintenance that are not yet understood. Our primary goal is to understand the mechanisms of differentiation and protection by these cells.

Research Interests

    1. CD4+ T cell memory to blood stages of Plasmodium chabaudi, mouse malaria
    2. Effector function (Th1, Tfh) in memory cells in malaria
    3. Vaccine strategies to generate protective effector memory T cells
    4. Mechanisms of Cerebral Malaria pathogenesis
    5. T cell memory and cytokines in P. Falciparum infection in collaboration with field laboratories
    6. Techniques: Multi-color flow cytometry, transcriptomics, adoptive T cell transfer using T cell receptor Transgenic mice, in vivo studies

Select Publications

  1. The contribution of Plasmodium chabaudi to our understanding of malaria.
    Stephens R, Culleton RL, Lamb TJ.
    Trends in parasitology. 2012; 28(2):73-82. PMID:
  2. Early Decision: Effector and Effector Memory T Cell Differentiation in Chronic Infection.
    Opata MM, Stephens R.
    Current immunology reviews. 2013; 9(3):190-206. PMID:
  3. IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.
    Carpio VH, Opata MM, Montañez ME, Banerjee PP, Dent AL, Stephens R.
    PloS one. 2015; 10(12):e0144654. PMID:
  4. Early effector cells survive the contraction phase in malaria infection and generate both central and effector memory T cells.
    Opata MM, Carpio VH, Ibitokou SA, Dillon BE, Obiero JM, Stephens R.
    Journal of immunology . 2015; 194(11):5346-54. PMID:
  5. Effector memory Th1 CD4 T cells are maintained in a mouse model of chronic malaria.
    Stephens R, Langhorne J.
    PLoS pathogens. 2010; 6(11):e1001208. PMID:

» PubMed

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