The Texas Southern University Substance Use\, Mental He alth HIV/AIDS Prevention Education (S.H.A.P.E.) Initiative (TSI) is a \;university and community-based coll aborative providing sexual health and substance use clinical services\, ed ucation\, \;outreach\, cas e management\, and service navigation. Based at Texas Southern University (TSU)\, it was established in 2014 to \;provide HIV and Hepatitis-C (HCV) sexual health screenings a nd outreach to ethnic and sexual minority students and \;residents throughout the Greater 3rd and 5t h ward communities. TSI has since then increased its service offerings to include \;expanded screeni ngs for sexually transmitted infections\, comprehensive substance use asse ssments\, evidence-based \;intervention programming\, and client and service provider education trai ning. \;Furthermore\, TSI expanded its geographical \;footprint by implementing service delivery throughout the City of Housto n and Harris\, Galveston\, and Chambers counties. To \;date\, it has collectively served more than 7 \,000 recipients\, the majority of whom identify as a member of an ethnic minority \;group. The TSI collaborative is designed and has subsequently evolved to become a synergi stic and culturally responsive \;approach to persistent sexual health disparities plaguing diverse e thnic and sexual minority community groups. This \;presentation will highlight TSI&rsquo\;s commitme nt to addressing sexual health conflicts underlying prominent sexual healt h \;disparities and its ap proach to reframing the sexual narrative.