Allen JA, Coe JW, Davoren JE, Dounay AB, Efremov IV, Gray DL et al. Heteroaromatic compounds and their use as Dopamine D1 ligands. Patent application. Pfizer, Inc., assignee. World Intellectual Property Organization (WIPO) WO2014072881. (2014) May 15.
Sassano MF, Allen JA, Jin J, Setola V, Wetsel WC, Caron MG, Roth BL. D2 Functionally Selective Ligands: Novel Therapeutics? Eiden LE, editor. Boston: Academic Press; (2014). Catecholamine Research in the 21st Century; p.105.
Dichter GS, Damiano CA and Allen JA. Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings. (2012) Journal of Neurodevelopmental Disorders July 19; 4:20
Huang HS*, Allen JA*, Mabb AM, Mirilyala J, Taylor-Blake B, Sciaky N, Dutton JW, Lee HM, Chen X, Jin J, Bridges AS, Zylka M, Roth BL and Philpot, BD. Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons. (2012) Nature Jan 12;485,185–189.(2012) (*, equal first author contribution)
Allen JA and Roth BL. Strategies to discover unexpected targets for drugs active at G protein-coupled receptors. (2011) Annual Review of Pharmacology and Toxicology Feb 10;51:117-44.
Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, Caron MG, Javitch JA, Roth BL and Jin J. Discovery of b-arrestin-biased Dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. (2011) Proceedings of the National Academy of Sciences Nov 8;108 (45):18488-93.
Allen JA, Yadav PN, Setola V, Farrell MS and Roth BL. Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo. (2011) Translational Psychiatry 1, e33; doi:10.1038/tp.2011.35 (epub 16 Aug. 2011)
Marder SR, Roth BL, Sullivan PF, Scolnick EM, Nestler EJ, Geyer MA, Weinberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, Law AJ, Campbell B, Krystal JH, Moghaddam B,Sawa A, Caron MG, George SR, Allen JA, and Solis M. Advancing drug discovery for schizophrenia. (2011) Annals of the New York Academy of Sciences Oct;1236 (1):30-43.
Kozikowski AP, Cho SJ, Jensen NH, Allen JA, Svennebring AM, and Roth BL.HTS and rational drug design to generate a class of 5-HT2C-selective ligands for possible use in schizophrenia. (2010) ChemMedChem Aug 2;5(8):1221-5.
Dong S, Allen JA, Farrell MS, and Roth BL. A chemical-genetic approach for precise spatio-temporal control of cellular signaling. (2010) Molecular Biosystems Aug;6(8):1376-80
Strachan R, Allen JA, Sheffler D and Roth BL. p90Ribosomal S6 kinase 2, a novel GPCR kinase, is required for growth factor-mediated attenuation of GPCR signaling. (2010) Biochemistry Mar;49(12):2657-71.
Allen JA, Yu JZ, Dave R, Bhatnagar A, Roth BL and Rasenick MM. Caveolin-1 and lipid microdomains regulate Gαs trafficking and attenuate Gαs/adenylyl cyclase signaling. (2009) Molecular Pharmacology Nov;76(5):1082-93.
Jones KA, Srivastava DP, Allen JA, Strachan RT, Roth BL and Penzes P. Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling.(2009) Proceedings of the National Academy of Sciences Nov 17;106(46):19575-19580
Alexander GM, Rogan SC, Abbas AI, Armbruster BN, Pei Y, Allen JA, Nonneman RJ, Moy SS, Nicolelis MA, McNamara JO and Roth BL. Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors. (2009) Neuron Jul 16;63(1):27-39.
Huang XP, Setola V, Yadav PN, Allen JA, Rogan SC, Hanson SJ, Revankar C, Robers M, Doucette C and Roth BL.Parallel functional activity profiling reveals valvulopathogens are potent 5-HT2B receptor agonists: implications for drug safety assessment. (2009) Molecular Pharmacology Oct;76(4):710-22.
Yan F, Bikbulatov RV, Mocanu V, Dicheva N, Parker CE, Wetsel WC, Mosier PD, Westkaemper RB, Allen JA, Zjawiony JK, and Roth BL. Structure-based design, synthesis, biochemical and pharmacological characterization of novel Salvinorin A analogues as active state probes of theκ-opioid receptor. (2009) Biochemistry Jul28;48(29):6898-908.
Yu, JZ, Dave RH, Allen JA, Sarma T, Rasenick MM. Cytosolic Gαs acts as an intracellular messenger to increase microtubule dynamics and promote neurite outgrowth. (2009) Journal of Biological Chemistry Apr 17;284(16):10462-72.