Wissam Khalife, MD, FACC, MAAC
Wissam Khalife, MD, FACC, MAAC
Associate Professor
Director, Advanced Heart Failure, Transplant and LVAD Program
Director, Advance Heart Failure/Transplant Fellowship Program
Holder, the Stubbs Family Professorship in Cardiology
Division: Cardiology
Department: Internal Medicine

Dr. Khalife is an Assistant Professor of Medicine at the UTMB Division of Cardiology. His educational background includes Heart Failure/Transplant Fellowship at Baylor College of Medicine/Texas Heart Institute and Cardiology Fellowship at UTMB. He is Board certified in Internal Medicine, Cardiovascular disease, Heart Failure and transplantation, Echocardiography, and Nuclear Cardiology. He was awarded the title of Master of the American Academy of Cardiology in 2010.

Dr. Khalife is currently the Interim Director of the Heart Failure/Transplant and Left ventricular assist device Program at UTMB. He is interested in invasive cardiology, invasive heart failure and transplant as well as cardiology imaging. He has multiple ongoing research projects and many publications.

Clinical Expertise
  1. Heart Failure and Transplantation
  2. Invasive Cardiology and Invasive Heart Failure
  3. Cardiac Imaging
Research Interests
  1. Diastolic Heart Failure: etiology and management
  2. Effects of exercise and life style modification on heart failure
  3. Radial approach for coronary angiogram: an academic institutional experience
Select Publications
  1. Sirolimus-induced alveolar hemorrhage. Wissam I. Khalife, Kogoj B, Biswajit Kar. J Heart Lung Transplant. 2007 Jun;26(6):652-7. Epub 2007 Apr 16.
  2. The TandemHeart pVAD in the treatment of acute fulminant myocarditis. Wissam I. Khalife, Biswajit Kar. Tex Heart Inst J. 2007;34(2):209-13.
  3. Treatment of subclinical hypothyroidism reverses ischemia and prevents myocyte loss and progressive LV dysfunction in hamsters with dilated cardiomyopathy. Wissam I Khalife, Tang YD, Kuzman JA, Thomas TA, Anderson BE, Said S, Tille P, Schlenker EH, Gerdes AM. Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2409-15. Epub 2005 Jul 15.
  4. Impending cardiac tamponade as a primary presentation of hypothyroidism: case report and review of literature. Andru K Karu, Wissam I Khalife, Robert Houser, John Van Derwoude. Endocr Pract. 2005 Jul-Aug;11(4):265-71.
  5. Pulmonary lymphangioleiomyomatosis in a postmenopausal woman: case report with review of literature. Wissam I. Khalife, Fade Mahmoud, Eric Larson, Richard Hardie. S D J Med. 2005 Apr;58(4):139-43. Review.
  6. Respiratory failure secondary to methemoglobinemia induced by benzocaine: a case report. Wissam I Khalife, Rong Wang, Jihad Khalil. S D J Med. 2004 Apr;57(4):145-7.
  7. Dilated cardiomyopathy, inferior myocardial infarction and severe mitral regurgutation as cardiac complications of Berardinelli-Seip syndrome. Wissam I. Khalife, Manal Mourtada, Jihad Khalil. Tex Heart Inst J, June 2008;35(2):1-4.
  8. Heart disease in patients with HIV/ AIDS: An emerging clinical problem. Muralikrishna Gopalakrishamoorthy, Archana Bhaskaran, Wissam I. Khalife, N.A. Barbagelata. Current Cardiology Reviews 2009, Volume 05, No. 02.
  9. Renal angiomyolipoma: clinical study with review of literature. Wissam I Khalife, Manal C. Mourtada, Sami Zeineddine. Lebanese University. Volume: 1, Pages: 1-50. October 1999.
  10. Diastolic Dysfunction (DD) is a useful marker to risk stratify patients with frequent COPD eexacerbations and normal left ventricular ejection fraction (LVEF). Ghassan Abusaid, Wissam I Khalife, N A Barbagelata, Gulshan Sharma, Enrique Tuero. Abstract presented at the 12th Annual Scientific meeting of the Heart Failure Society of America (September 21-24, 2008, Toronto, ON, Canada).
Degree/Training CompletedYearName & Location
B.A.1992Lebanese University
M.D.1999Lebanese University
Residency Traditional Year2000Lebanese University
Residency Internal Medicine2005University of South Dakota
Fellowship Heart Failure & Cardiac Transplantation2006Texas Heart Institute/Baylor College of Medicine
Fellowship Cardiovascular Disease2009University of Texas Medical Branch, Galveston, TX