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Bone Marrow Pathology Exam (8000101024)
Test Mnemonic:
Specimen Requirements:
Test Included:

Bone Marrow Aspirate

Bone Marrow Biopsy


Kits and extra collection needles for the procedure are available in Materials Management Warehouse, Room 2.610.  Clinicians can call ahead to 22695 or 22692 and it will be waiting for them at the window.


1. Bone Marrow Aspirate: EDTA (Lavender-top tube), Sodium Heparin (Green-top tube).

2. Bone Marrow Biopsy: Core biopsy is collected first in RPMI media, then it will be transferred to 10% buffered formalin.

Minimum Volume:

Bone Marrow Aspirate: 1ml EDTA (Lavender-top tube) and 1 ml Sodium Heparin (Green-top tube).

Bone Marrow Biopsy: 1.5 cm length core biopsy.


Specimens must be delivered to Hematopathology Lab at CSW 7.412 within 30 minutes of completion of the procedure in-house.

Specimens collected in CLC or LCC need to be delivered to Hematopathology Lab at CSW 7.412 by 11:30 am of the collection date.


24 hours at 16-28 C

Causes for Rejection:

Insufficient identification, inappropriate anticoagulants, specimen collected on weekends or holidays and refrigerated or frozen specimens.

Reference Range:

By report (reports may vary based on instrumentation, patient age and sex).

Turnaround Time:

72 hours


Bone Marrow Aspirate: Push smears (at least 2 smears) and Crush smears (at least 4 smears) are prepared at the patient bedside.  At least one of each are stained with Wright-Giemsa stain.  At least one crush smear is stained with Prussian Blue stain.

Bone Marrow Biopsy: Touch smears (at least 2 smears) at the patient bedside.  At least one touch smear will be stained with Wright-Giemsa stain.


Galveston Campus: Monday-Friday 8:00-11:00 AM (except holidays).  Specimens from Hem/Oncology Clinic are accepted until 2:00 PM with prior approval.

CLC/LCC Campus: Moday-Friday specimens need to be in Hematopathology Lab at CSW 7.412 by 11:30 AM.


Bone Marrow, Bone Marrow Exam

Clinical Indication:

Assessment of cellularity and morphologic abnormalities present in bone marrow aspirate and biopsy smears.

CPT 4 Code:

88313, 85097, 88305,88311


If applicable, state clinical information that is required to be provided with specimen.

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent.
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