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Anti-SSA (Ro) Antibody (8000100230)
Test Mnemonic:
Specimen Requirements:
Collection:

Serum separator tube (SST)

Red top serum tube with no additive

Container:

Serum separator tube (SST)

Red top serum tube with no additive

Minimum Volume:

1 mL of serum

Storage/Transport:

Refrigerate (2-8°C) up to 7 days; Samples should be frozen (<-20°C)

Specimen Preparation:

Within 2 hours of collection, centrifuge. Serum collected in a red top tube should be removed from the red cells if testing will be delayed.

Stability:

Refrigerate (2-8°C) up to 7 days; Samples should be frozen (<-20°C)

Causes for Rejection:

Improper collection, gross hemolysis.  Specimen container unlabeled or labeled incorrectly. No date and time of collection on requisition form.

Reference Range:

Positive - Antibody detected. 

Negative - No antibody detected

 

Turnaround Time:

Test is performed in batch, once per day, six days per week.

Methodology:

Multiplexing bead immunoassay

Performed:

Clinical Microbiology

Synonyms:

SSA Antibody; Ro Antibody; ENA Antibodies

Clinical Indication:

Autoimmune disease testing

CPT 4 Code:

86235

Note:

SSA (Ro) antibody is seen in 70-75% of Sjogren syndrome cases, 30-40% of systemic lupus erythematosus (SLE), and 5-10% of progressive systemic sclerosis (PSS)

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent.
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