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SyphilisTotal (IgG/IgM) Screen (8000101363)
Test Mnemonic:
Specimen Requirements:
Test Included:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Syphilis Total. Reactive test results are automatically tested for RPR titer and TP-PA confirmation tests, as needed</span></span>.</p> <p> If Syph total is reactive, RPR and TPPA must be tested within 5 days of collection.&nbsp;</p>

Collection:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Serum separator tube (SST), Rapid serum tube (RST) or Red top serum tube with no additive</span></span></p>

Container:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Serum separator tube (SST), Rapid serum tube (RST)or Red top serum tube with no additive</span></span></p>

Minimum Volume:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">3 mL of blood (1 ml of serum)</span></span></p>

Storage/Transport:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Refrigerate (2-8&deg;C) up to 7 days; Samples should be frozen (&lt;-20&deg;C)</span></span></p>

Specimen Preparation:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Within two hours of collection, centrifuge. Serum collected in a red top tube should be removed from the red cells if testing will be delayed.</span></span></p>

Stability:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Refrigerate (2-8&deg;C) up to 7 days; Samples should be frozen (&lt;-20&deg;C)</span></span></p>

Causes for Rejection:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Insufficient quantity, gross hemolysis, lipemia.&nbsp; Specimen container unlabeled or labeled incorrectly. No date and time of collection or collector completed.</span></span></p>

Reference Range:

<p style="line-height: normal; margin-bottom: 0pt;"> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Non-reactive</span></span></p>

Turnaround Time:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;"><span class="TextRun SCXW210887196 BCX0" data-contrast="auto" lang="EN-US" style="accent-color: auto; place-content: normal; place-items: normal; place-self: auto; alignment-baseline: auto; anchor-name: none; animation: 0s ease 0s 1 normal none running none; animation-composition: replace; app-region: none; appearance: none; aspect-ratio: auto; backdrop-filter: none; backface-visibility: visible; background: none 0% 0% / auto repeat scroll padding-box border-box rgba(0, 0, 0, 0); background-blend-mode: normal; baseline-shift: 0px; baseline-source: auto; border-image: none 100% / 1 / 0 stretch; border-color: rgb(0, 0, 0); border-collapse: separate; border-end-end-radius: 0px; border-end-start-radius: 0px; border-width: 0px; border-style: none; border-spacing: 0px; border-start-end-radius: 0px; border-start-start-radius: 0px; border-radius: 0px; inset: auto; box-decoration-break: slice; box-shadow: none; 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scrollbar-gutter: auto; scrollbar-width: auto; shape-image-threshold: 0; shape-margin: 0px; shape-outside: none; shape-rendering: auto; speak: normal; stop-color: rgb(0, 0, 0); stop-opacity: 1; stroke: none; stroke-dasharray: none; stroke-dashoffset: 0px; stroke-linecap: butt; stroke-linejoin: miter; stroke-miterlimit: 4; stroke-opacity: 1; stroke-width: 1px; tab-size: 8; table-layout: auto; text-align-last: auto; text-anchor: start; text-combine-upright: none; text-decoration-style: solid; text-decoration-color: rgb(0, 0, 0); text-decoration-skip-ink: auto; text-emphasis: none rgb(0, 0, 0); text-emphasis-position: over; text-orientation: mixed; text-overflow: clip; text-rendering: auto; text-shadow: none; text-size-adjust: auto; text-spacing-trim: normal; text-underline-offset: auto; text-underline-position: auto; text-wrap-style: initial; timeline-scope: none; touch-action: auto; transform: none; transform-box: view-box; transform-origin: 0px 0px; transform-style: flat; transition: all; translate: none; unicode-bidi: normal; user-select: text; vector-effect: none; vertical-align: baseline; view-timeline: none; view-transition-class: none; view-transition-name: none; visibility: visible; border-block-end: 0px none rgb(0, 0, 0); border-block-start: 0px none rgb(0, 0, 0); border-inline-end: 0px none rgb(0, 0, 0); -webkit-border-image: none; border-inline-start: 0px none rgb(0, 0, 0); -webkit-box-align: stretch; -webkit-box-decoration-break: slice; -webkit-box-direction: normal; -webkit-box-flex: 0; -webkit-box-ordinal-group: 1; -webkit-box-orient: horizontal; -webkit-box-pack: start; -webkit-font-smoothing: auto; -webkit-line-break: auto; -webkit-line-clamp: none; -webkit-locale: &quot;en-US&quot;; block-size: auto; margin-block: 0px; margin-inline: 0px; -webkit-mask-box-image-source: none; -webkit-mask-box-image-slice: 0 fill; -webkit-mask-box-image-width: auto; -webkit-mask-box-image-outset: 0; -webkit-mask-box-image-repeat: stretch; max-block-size: none; max-inline-size: none; min-block-size: 0px; min-inline-size: 0px; padding-block: 0px; padding-inline: 0px; -webkit-print-color-adjust: economy; -webkit-rtl-ordering: logical; -webkit-ruby-position: before; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-combine: none; -webkit-text-fill-color: rgb(0, 0, 0); -webkit-text-orientation: vertical-right; -webkit-text-security: none; -webkit-text-stroke-color: rgb(0, 0, 0); -webkit-user-drag: none; -webkit-user-modify: read-only; -webkit-writing-mode: horizontal-tb; white-space-collapse: preserve; width: auto; will-change: auto; word-break: normal; writing-mode: horizontal-tb; x: 0px; y: 0px; z-index: auto; zoom: 1;" xml:lang="EN-US"><span class="NormalTextRun SCXW210887196 BCX0">Test is performed in batch, once per day, six days a week</span></span></span></span></p> <p> L&amp;D/Newborn specimens tested 7 days a week.</p>

Methodology:

<p style="line-height: normal; margin-bottom: 0pt;"> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Multiplex immunoassay</span></span></p>

Performed:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Clinical Microbiology</span></span></p>

Synonyms:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">&nbsp;Syphilis</span></span></p>

Clinical Indication:

<p style="line-height: normal; margin-bottom: 0pt;"> <span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;">Intended for the qualitative detection of total antibodies to&nbsp;<i style="font-family: Georgia; font-size: small;">Treponema pallidium&nbsp;</i>and should be used in conjunction with other laboratory tests and clinical findings to aid in the diagnosis of syphilis infection.</span></span></p>

Patient Preparation :

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Routine venipuncture</span></span></p>

CPT 4 Code:

<p> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">86780</span></span></p>

Note:

<p style="line-height: normal; margin-bottom: 0pt;"> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Specimens with positive Syphilis Total results are automatically tested for RPR titer and a confirmatory treponemal test (Treponema pallidum partical agglutination test), as needed.</span></span></p> <p style="line-height: normal; margin-bottom: 0pt;"> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">For patients diagnosed with syphilis (i.e., positive Total and confirmatory test), the CDC recommends that response to therapy be assessed by RPR test (a 4-fold decline in titer, or undetectable RPR titer) after 6 months.&nbsp;</span></span></p> <p style="line-height: normal; margin-bottom: 0pt;"> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Tests are performed on all obstetrics patients regardless of previous results.&nbsp; If there is no previous patient data, the requested tests are performed.&nbsp;</span></span></p> <p style="line-height: normal; margin-bottom: 0pt;"> <span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">VDRL test is performed on CSF samples as a Sendout test for patients with positive serum test results, only.</span></span></p>

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent.
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